ID V9GXW0_MOUSE Unreviewed; 197 AA.
AC V9GXW0;
DT 19-FEB-2014, integrated into UniProtKB/TrEMBL.
DT 19-FEB-2014, sequence version 1.
DT 27-MAR-2024, entry version 62.
DE SubName: Full=Cell division cycle 20 {ECO:0000313|Ensembl:ENSMUSP00000139345.2};
DE Flags: Fragment;
GN Name=Cdc20 {ECO:0000313|Ensembl:ENSMUSP00000139345.2,
GN ECO:0000313|MGI:MGI:1859866};
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090 {ECO:0000313|Ensembl:ENSMUSP00000139345.2, ECO:0000313|Proteomes:UP000000589};
RN [1] {ECO:0000313|Ensembl:ENSMUSP00000139345.2, ECO:0000313|Proteomes:UP000000589}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000139345.2,
RC ECO:0000313|Proteomes:UP000000589};
RX PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
RA Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X.,
RA Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y.,
RA Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S.,
RA Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R.,
RA Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K.,
RA Eichler E.E., Ponting C.P.;
RT "Lineage-specific biology revealed by a finished genome assembly of the
RT mouse.";
RL PLoS Biol. 7:E1000112-E1000112(2009).
RN [2] {ECO:0000313|Ensembl:ENSMUSP00000139345.2}
RP IDENTIFICATION.
RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000139345.2};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the WD repeat CDC20/Fizzy family.
CC {ECO:0000256|ARBA:ARBA00006445}.
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DR MaxQB; V9GXW0; -.
DR PeptideAtlas; V9GXW0; -.
DR ProteomicsDB; 309916; -.
DR Antibodypedia; 3864; 775 antibodies from 38 providers.
DR Ensembl; ENSMUST00000183942.2; ENSMUSP00000139345.2; ENSMUSG00000006398.16.
DR AGR; MGI:1859866; -.
DR MGI; MGI:1859866; Cdc20.
DR VEuPathDB; HostDB:ENSMUSG00000006398; -.
DR GeneTree; ENSGT00950000183104; -.
DR HOGENOM; CLU_1393084_0_0_1; -.
DR ChiTaRS; Cdc20; mouse.
DR Proteomes; UP000000589; Chromosome 4.
DR Bgee; ENSMUSG00000006398; Expressed in cleaving embryo and 224 other cell types or tissues.
DR ExpressionAtlas; V9GXW0; baseline and differential.
DR GO; GO:0010997; F:anaphase-promoting complex binding; IEA:InterPro.
DR GO; GO:0097027; F:ubiquitin-protein transferase activator activity; IEA:InterPro.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR InterPro; IPR024977; Apc4-like_WD40_dom.
DR InterPro; IPR033010; Cdc20/Fizzy.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR PANTHER; PTHR19918; CELL DIVISION CYCLE 20 CDC20 FIZZY -RELATED; 1.
DR PANTHER; PTHR19918:SF3; CELL DIVISION CYCLE PROTEIN 20 HOMOLOG; 1.
DR Pfam; PF12894; ANAPC4_WD40; 1.
DR SMART; SM00320; WD40; 2.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
DR PROSITE; PS50082; WD_REPEATS_2; 1.
PE 1: Evidence at protein level;
KW Proteomics identification {ECO:0007829|EPD:V9GXW0,
KW ECO:0007829|PeptideAtlas:V9GXW0};
KW Reference proteome {ECO:0000313|Proteomes:UP000000589};
KW WD repeat {ECO:0000256|PROSITE-ProRule:PRU00221}.
FT REPEAT 103..144
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT DOMAIN 104..159
FT /note="Anaphase-promoting complex subunit 4-like WD40"
FT /evidence="ECO:0000259|Pfam:PF12894"
FT NON_TER 1
FT /evidence="ECO:0000313|Ensembl:ENSMUSP00000139345.2"
SQ SEQUENCE 197 AA; 21945 MW; A8CC2E0192591E59 CRC64;
XNGFDVEEAK ILRLSGKPQN APEGYQNRLK VLYSQKATPG SSRKTCRYIP SLPDRILDAP
EIRNDYYLNL VDWSSGNVLA VALDNSVYLW NAGSGDILQL LQMEQPGDYI SSVAWIKEGN
YLAVGTSNAE VQLWDVQQQK RLRNMTSHSA RVSSLSWNSY ILSRLWHGVP GSPISWQQEE
EPVTGTFAFG TSAQGPV
//
