ID V9HEA0_9CLOT Unreviewed; 298 AA.
AC V9HEA0;
DT 19-FEB-2014, integrated into UniProtKB/TrEMBL.
DT 19-FEB-2014, sequence version 1.
DT 27-MAR-2024, entry version 44.
DE RecName: Full=SIS domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=CSBG_01485 {ECO:0000313|EMBL:EEH97859.2};
OS Clostridium sp. 7_2_43FAA.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC Clostridium.
OX NCBI_TaxID=457396 {ECO:0000313|EMBL:EEH97859.2, ECO:0000313|Proteomes:UP000017809};
RN [1] {ECO:0000313|EMBL:EEH97859.2, ECO:0000313|Proteomes:UP000017809}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=7_2_43FAA {ECO:0000313|EMBL:EEH97859.2,
RC ECO:0000313|Proteomes:UP000017809};
RG The Broad Institute Genome Sequencing Platform;
RA Earl A., Ward D., Feldgarden M., Gevers D., Allen-Vercoe E., Strauss J.,
RA Ambrose C., Young S.K., Zeng Q., Gargeya S., Fitzgerald M., Haas B.,
RA Abouelleil A., Alvarado L., Arachchi H.M., Berlin A., Chapman S.B.,
RA Gearin G., Goldberg J., Griggs A., Gujja S., Hansen M., Heiman D.,
RA Howarth C., Larimer J., Lui A., MacDonald P.J.P., McCowen C.,
RA Montmayeur A., Murphy C., Neiman D., Pearson M., Priest M., Roberts A.,
RA Saif S., Shea T., Sisk P., Stolte C., Sykes S., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Clostridium sp. 7_2_43FAA.";
RL Submitted (JAN-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EEH97859.2}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; ACDK02000028; EEH97859.2; -; Genomic_DNA.
DR RefSeq; WP_008678847.1; NZ_JH815222.1.
DR AlphaFoldDB; V9HEA0; -.
DR STRING; 457396.CSBG_01485; -.
DR GeneID; 65399159; -.
DR eggNOG; COG1737; Bacteria.
DR HOGENOM; CLU_055769_1_1_9; -.
DR OrthoDB; 2930at2; -.
DR Proteomes; UP000017809; Unassembled WGS sequence.
DR GO; GO:0097367; F:carbohydrate derivative binding; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:1901135; P:carbohydrate derivative metabolic process; IEA:InterPro.
DR CDD; cd05013; SIS_RpiR; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR000281; HTH_RpiR.
DR InterPro; IPR047640; RpiR-like.
DR InterPro; IPR035472; RpiR-like_SIS.
DR InterPro; IPR001347; SIS_dom.
DR InterPro; IPR046348; SIS_dom_sf.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR PANTHER; PTHR30514; GLUCOKINASE; 1.
DR PANTHER; PTHR30514:SF18; RPIR-FAMILY TRANSCRIPTIONAL REGULATOR; 1.
DR Pfam; PF01418; HTH_6; 1.
DR Pfam; PF01380; SIS; 1.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR SUPFAM; SSF53697; SIS domain; 1.
DR PROSITE; PS51071; HTH_RPIR; 1.
DR PROSITE; PS51464; SIS; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000017809}.
FT DOMAIN 10..86
FT /note="HTH rpiR-type"
FT /evidence="ECO:0000259|PROSITE:PS51071"
FT DOMAIN 132..270
FT /note="SIS"
FT /evidence="ECO:0000259|PROSITE:PS51464"
SQ SEQUENCE 298 AA; 33182 MW; AF92AB5E0CE18707 CRC64;
MDNNLNENSK DLMRLIQARF SRLSKGQKLI AEYILKNYDK AAFMTAAKLG VSVGVSESTV
VRFANELGFS GYPKLQKALQ ELIKNKLTTV QRLELSNDYV SEGYALKGVL KADMENIRAT
LEKINYNTFE EVVNKIFEAK RIYIIGLRSS TALAEFLGFY LNIILQNVKT VGYGISDIFE
QMINVEEGDL VIGIGFPRYA SRTIDALAFA QDRGADVVAI TDSLLSPLAS KSDYALIAQS
NMASFVDSLV APLSVINALI IAVGMREKQS ITDTFNNLEL IWKDYNVYSY NNKNVGDD
//
