ID V9IHA5_APICE Unreviewed; 480 AA.
AC V9IHA5;
DT 19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT 19-MAR-2014, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE RecName: Full=beta-N-acetylhexosaminidase {ECO:0000256|ARBA:ARBA00012663};
DE EC=3.2.1.52 {ECO:0000256|ARBA:ARBA00012663};
GN ORFNames=ACCB06931 {ECO:0000313|EMBL:AEY60037.1};
OS Apis cerana (Indian honeybee).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Hymenoptera; Apocrita; Aculeata; Apoidea;
OC Anthophila; Apidae; Apis.
OX NCBI_TaxID=7461 {ECO:0000313|EMBL:AEY60037.1};
RN [1] {ECO:0000313|EMBL:AEY60037.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Brain {ECO:0000313|EMBL:AEY60037.1};
RA Sun L., Zheng H., Wang Y., Xie X., Zhu Y., Gu W., Wang S.;
RT "Decoding the brain transcriptome of the Eastern honeybee (Apis cerana)
RT based on pyrosequencing.";
RL Submitted (NOV-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=Hydrolysis of terminal non-reducing N-acetyl-D-hexosamine
CC residues in N-acetyl-beta-D-hexosaminides.; EC=3.2.1.52;
CC Evidence={ECO:0000256|ARBA:ARBA00001231};
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 20 family.
CC {ECO:0000256|ARBA:ARBA00006285}.
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DR EMBL; JR045710; AEY60037.1; -; mRNA.
DR AlphaFoldDB; V9IHA5; -.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0004563; F:beta-N-acetylhexosaminidase activity; IEA:UniProtKB-EC.
DR GO; GO:0102148; F:N-acetyl-beta-D-galactosaminidase activity; IEA:UniProtKB-EC.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR CDD; cd06565; GH20_GcnA-like; 1.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR InterPro; IPR015883; Glyco_hydro_20_cat.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR InterPro; IPR038901; HEXDC-like.
DR PANTHER; PTHR21040:SF13; BETA-N-ACETYLHEXOSAMINIDASE; 1.
DR PANTHER; PTHR21040; UNCHARACTERIZED; 1.
DR Pfam; PF00728; Glyco_hydro_20; 1.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
PE 2: Evidence at transcript level;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 7..28
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 152..297
FT /note="Glycoside hydrolase family 20 catalytic"
FT /evidence="ECO:0000259|Pfam:PF00728"
SQ SEQUENCE 480 AA; 55269 MW; CB64A43C6CB6D850 CRC64;
MTRLRGRASL MIIIMISFTL LIIIYHILGN EVKDITSNKL SPRLKIEEVY PLSDLTENPL
SIARKQQIEA HIMGKLKSGG GKIFSDFNYG KSRIEVPLFK GHKIVHLDLK GAPPKASYYK
YLLRLLKKLG ATGILIEYED MFPFEGIIQN ISAGNCYTKR DITNIQKLAN ENQLIVIPLI
QTFGHMEFVL KLDKYKDYRE VSRYPQVLCP TYNKTLPLIY EMIDQIIEAH PDIKHLHIGA
DEVYQIGECS RCSDIIIKKQ WGKKQLFLDH VSKVAKYIKN KYPELTVLMW DDEFREISSE
EIIDRGLHLM VEPVVWKYTT DPGVSLTDQL WESYASVWKN IWIATAFKGA TAPDRYYTDI
AYHIENHQRW LEIINRYSTQ IRFKGAILTG WQRYDHFSVL CELLPSAIPS LAVNLAILQA
PDLCRFPIEV PTSVLQALQC EGIISLNIPE PQYGWTKCNY HGVSIYAATL SIVFFDSRSQ
//
