ID V9IIJ1_APICE Unreviewed; 448 AA.
AC V9IIJ1;
DT 19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT 19-MAR-2014, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE SubName: Full=RING finger protein 13 {ECO:0000313|EMBL:AEY60119.1};
GN ORFNames=ACCB07259 {ECO:0000313|EMBL:AEY60119.1};
OS Apis cerana (Indian honeybee).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Hymenoptera; Apocrita; Aculeata; Apoidea;
OC Anthophila; Apidae; Apis.
OX NCBI_TaxID=7461 {ECO:0000313|EMBL:AEY60119.1};
RN [1] {ECO:0000313|EMBL:AEY60119.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Brain {ECO:0000313|EMBL:AEY60119.1};
RA Sun L., Zheng H., Wang Y., Xie X., Zhu Y., Gu W., Wang S.;
RT "Decoding the brain transcriptome of the Eastern honeybee (Apis cerana)
RT based on pyrosequencing.";
RL Submitted (NOV-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-
CC pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
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DR EMBL; JR046038; AEY60119.1; -; mRNA.
DR RefSeq; XP_016920589.1; XM_017065100.1.
DR RefSeq; XP_016920590.1; XM_017065101.1.
DR RefSeq; XP_016920591.1; XM_017065102.1.
DR RefSeq; XP_016920592.1; XM_017065103.1.
DR AlphaFoldDB; V9IIJ1; -.
DR GeneID; 108003037; -.
DR KEGG; acer:108003037; -.
DR OrthoDB; 5474929at2759; -.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProt.
DR GO; GO:0012505; C:endomembrane system; IEA:UniProt.
DR GO; GO:0043229; C:intracellular organelle; IEA:UniProt.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0043227; C:membrane-bounded organelle; IEA:UniProt.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd02123; PA_C_RZF_like; 1.
DR CDD; cd12087; TM_EGFR-like; 1.
DR Gene3D; 3.50.30.30; -; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR046450; PA_dom_sf.
DR InterPro; IPR003137; PA_domain.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR InterPro; IPR044744; ZNRF4/RNF13/RNF167_PA.
DR PANTHER; PTHR47168:SF6; PROTEASE-ASSOCIATED (PA) RING_U-BOX ZINC FINGER FAMILY PROTEIN; 1.
DR PANTHER; PTHR47168; RING ZINC FINGER DOMAIN SUPERFAMILY PROTEIN-RELATED; 1.
DR Pfam; PF02225; PA; 1.
DR Pfam; PF13639; zf-RING_2; 1.
DR SMART; SM00184; RING; 1.
DR SUPFAM; SSF52025; PA domain; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 2: Evidence at transcript level;
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00175}.
FT SIGNAL 1..26
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 27..448
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5004777243"
FT TRANSMEM 175..199
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 232..274
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT REGION 285..364
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 301..317
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 448 AA; 50497 MW; 400565809EFFF6A6 CRC64;
MKQCCLSHQL QLWLMFLVFC VMCNRADILV FSAAARHQIE EEFRDMPARF GGLIPSEGIK
GMVVYAEPAT ACHEIQSPPN STSYIGNWIS LIARYNCSFE RKVRMAQKAG YDAVIIHNVN
SNKLEPMLAK DPTGIIIPSV FVSEITGLII KENYLYDELY FILINDDSPF NITHLLLPFA
IVVGICFLIM VIFMIVRCIK DRRRQQRHRL PNSSLKKIPT HKYTKGDPYE TCAICLDDYA
EGEKLRVLPC AHAYHTKCID PWLTKNRRVC PVCKRKVFAA DEQVVTDESD SDADDTTPLI
REGHQGTQGG TFSRQRENPF NRARRSQTRQ HDIIHFNSSS DSEELLDTTD EEASISAGEP
SSGTVFRPFD IHSINGELPD LECSVSSTKP HTVNLYTDVE EFPAPVVQIT NCNIRTNSQT
SNSGGSVPIE SEATNFINTD SEEIDIHV
//
