ID V9K7C3_CALMI Unreviewed; 976 AA.
AC V9K7C3;
DT 19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT 19-MAR-2014, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE SubName: Full=Sorbin and SH3 domain-containing protein 2 {ECO:0000313|EMBL:AFO93851.1};
OS Callorhinchus milii (Ghost shark).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Chondrichthyes;
OC Holocephali; Chimaeriformes; Callorhinchidae; Callorhinchus.
OX NCBI_TaxID=7868 {ECO:0000313|EMBL:AFO93851.1};
RN [1] {ECO:0000313|EMBL:AFO93851.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Heart {ECO:0000313|EMBL:AFO93851.1};
RX PubMed=24402279; DOI=10.1038/nature12826;
RG International Elephant Shark Genome Sequencing Consortium;
RA Venkatesh B., Lee A.P., Ravi V., Maurya A.K., Lian M.M., Swann J.B.,
RA Ohta Y., Flajnik M.F., Sutoh Y., Kasahara M., Hoon S., Gangu V., Roy S.W.,
RA Irimia M., Korzh V., Kondrychyn I., Lim Z.W., Tay B.H., Tohari S.,
RA Kong K.W., Ho S., Lorente-Galdos B., Quilez J., Marques-Bonet T.,
RA Raney B.J., Ingham P.W., Tay A., Hillier L.W., Minx P., Boehm T.,
RA Wilson R.K., Brenner S., Warren W.C.;
RT "Elephant shark genome provides unique insights into gnathostome
RT evolution.";
RL Nature 505:174-179(2014).
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; JW861334; AFO93851.1; -; mRNA.
DR AlphaFoldDB; V9K7C3; -.
DR Gene3D; 2.30.30.40; SH3 Domains; 3.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR InterPro; IPR003127; SoHo_dom.
DR PANTHER; PTHR14167:SF56; DREBRIN-LIKE PROTEIN-RELATED; 1.
DR PANTHER; PTHR14167; SH3 DOMAIN-CONTAINING; 1.
DR Pfam; PF00018; SH3_1; 2.
DR Pfam; PF14604; SH3_9; 1.
DR Pfam; PF02208; Sorb; 1.
DR PRINTS; PR00499; P67PHOX.
DR PRINTS; PR00452; SH3DOMAIN.
DR SMART; SM00326; SH3; 3.
DR SMART; SM00459; Sorb; 1.
DR SUPFAM; SSF50044; SH3-domain; 3.
DR PROSITE; PS50002; SH3; 3.
DR PROSITE; PS50831; SOHO; 1.
PE 2: Evidence at transcript level;
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}.
FT DOMAIN 355..416
FT /note="SoHo"
FT /evidence="ECO:0000259|PROSITE:PS50831"
FT DOMAIN 738..797
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT DOMAIN 813..874
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT DOMAIN 917..976
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT REGION 1..97
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 185..221
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 422..466
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 536..556
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 618..729
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 28..43
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 73..97
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 185..204
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 624..649
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 650..666
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 667..707
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 976 AA; 109689 MW; 7E36E81AD092A63B CRC64;
MNTGYEAQAP DSDLWRSYGI NDNPRGALNG DAHSSSLTAK GFRSVRPNLS FPERKTPPQQ
VPSPPPRKES FNWYPLTNPS NSHAPSGSDQ GPINRSWPAL PTSNLQITSN VTCVTNEEEY
VQSASHLFEQ SSTHFSCSQQ APSDQASTLC KVVDRSNANA SLQTNYGHFQ ERKINTIKLT
LSERQKVANS SNTEHKSMPH SDVNPSLHSP FPGDKTEPER HTASLSIQIV PASVHTTEQG
PPPVYAADSG RKPHRDTAQV LNAPPCAQSS GDRLMAVNGN SITDSGSLMG NFQGSFSPSS
AYPLLASGNP NIVAMQHSRK MESMRTSQQS RSPGIDMISI DPLYRTSEEE KKVTVIKAPH
YAGIGPVDES GIPIAIRTTV DRPKDWYKTM FKQIHMVHKP DDDNDAYNAT YAYTHPDNYS
SFTSVQAHPP PKTHTYRPLS KSVSDSSAEF LKDSAPLPPP PPVPPPSHLR YREMVLTEKN
DWDPPDRKVD TRRYRAEPRS IFEYEPGKSS ILEQERPSSA TAAQLYKDKR FSEPQYVANK
GKMSQKSKKI KTAGSKVFSA HRAREVGLKH RVEEEDQEWV SGRINPDEID LENEPWYKFF
SELEFGRPPP KKLLDYVPER SPHVSTETIK TSLYNSSVER TIDRPTSARS SASDYRKRRK
SEPAVSHQRA QNDQAAQKSG DPQGLSNVSR KSLTSSSPSS PSRIKDQESP RYISEMGRYT
PRNQRETPDE ICRRLEQRER QPAKAIYDFK AQTAKELPFK KGDIVYILRQ IDQNWFEGEH
HGAVGIFPIS YVEKVPPMEK AQPARPPPPA EIREFGEAIA KYNFTADTNV ELSLRKGERI
KLVRRVDQNW YEGRIPGTNR QGIFPITYVD VLKKPQLKSA AEFSGPPLPH SYSSDRIHTL
GSTKPQRPAF MHDDLQSGGE PYQAMYNYNP RNEDELELKE GDIVDVMEKC DDGWFVGTSR
RSKLFGTFPG NYVKRL
//
