ID   V9KG14_CALMI            Unreviewed;       706 AA.
AC   V9KG14;
DT   19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT   19-MAR-2014, sequence version 1.
DT   27-MAR-2024, entry version 28.
DE   SubName: Full=Vascular cell adhesion protein 1-like protein {ECO:0000313|EMBL:AFO96739.1};
OS   Callorhinchus milii (Ghost shark).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Chondrichthyes;
OC   Holocephali; Chimaeriformes; Callorhinchidae; Callorhinchus.
OX   NCBI_TaxID=7868 {ECO:0000313|EMBL:AFO96739.1};
RN   [1] {ECO:0000313|EMBL:AFO96739.1}
RP   NUCLEOTIDE SEQUENCE.
RC   TISSUE=Ovary {ECO:0000313|EMBL:AFO96739.1};
RX   PubMed=24402279; DOI=10.1038/nature12826;
RG   International Elephant Shark Genome Sequencing Consortium;
RA   Venkatesh B., Lee A.P., Ravi V., Maurya A.K., Lian M.M., Swann J.B.,
RA   Ohta Y., Flajnik M.F., Sutoh Y., Kasahara M., Hoon S., Gangu V., Roy S.W.,
RA   Irimia M., Korzh V., Kondrychyn I., Lim Z.W., Tay B.H., Tohari S.,
RA   Kong K.W., Ho S., Lorente-Galdos B., Quilez J., Marques-Bonet T.,
RA   Raney B.J., Ingham P.W., Tay A., Hillier L.W., Minx P., Boehm T.,
RA   Wilson R.K., Brenner S., Warren W.C.;
RT   "Elephant shark genome provides unique insights into gnathostome
RT   evolution.";
RL   Nature 505:174-179(2014).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-
CC       pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
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DR   EMBL; JW864222; AFO96739.1; -; mRNA.
DR   AlphaFoldDB; V9KG14; -.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProt.
DR   GO; GO:0098609; P:cell-cell adhesion; IEA:InterPro.
DR   CDD; cd00096; Ig; 1.
DR   Gene3D; 2.60.40.10; Immunoglobulins; 7.
DR   InterPro; IPR007110; Ig-like_dom.
DR   InterPro; IPR036179; Ig-like_dom_sf.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR013098; Ig_I-set.
DR   InterPro; IPR003599; Ig_sub.
DR   InterPro; IPR003598; Ig_sub2.
DR   InterPro; IPR003989; VCAM-1.
DR   PANTHER; PTHR11640:SF164; MAM DOMAIN-CONTAINING GLYCOSYLPHOSPHATIDYLINOSITOL ANCHOR PROTEIN 1; 1.
DR   PANTHER; PTHR11640; NEPHRIN; 1.
DR   Pfam; PF07679; I-set; 1.
DR   Pfam; PF13895; Ig_2; 2.
DR   Pfam; PF13927; Ig_3; 3.
DR   PRINTS; PR01474; VCAM1.
DR   SMART; SM00409; IG; 7.
DR   SMART; SM00408; IGc2; 6.
DR   SUPFAM; SSF48726; Immunoglobulin; 7.
DR   PROSITE; PS50835; IG_LIKE; 6.
PE   2: Evidence at transcript level;
KW   Membrane {ECO:0000256|SAM:Phobius}; Signal {ECO:0000256|SAM:SignalP};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   SIGNAL          1..20
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           21..706
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5004778179"
FT   TRANSMEM        666..689
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          23..109
FT                   /note="Ig-like"
FT                   /evidence="ECO:0000259|PROSITE:PS50835"
FT   DOMAIN          218..302
FT                   /note="Ig-like"
FT                   /evidence="ECO:0000259|PROSITE:PS50835"
FT   DOMAIN          307..389
FT                   /note="Ig-like"
FT                   /evidence="ECO:0000259|PROSITE:PS50835"
FT   DOMAIN          394..478
FT                   /note="Ig-like"
FT                   /evidence="ECO:0000259|PROSITE:PS50835"
FT   DOMAIN          483..565
FT                   /note="Ig-like"
FT                   /evidence="ECO:0000259|PROSITE:PS50835"
FT   DOMAIN          570..651
FT                   /note="Ig-like"
FT                   /evidence="ECO:0000259|PROSITE:PS50835"
SQ   SEQUENCE   706 AA;  76047 MW;  DB578AD6F8B58869 CRC64;
     MPSTGCGLAV SLLLSLCTAG ATFELEVRPG REVWAREGQQ VTLSCRISGC LEPSPRLFWS
     KSGDSVVGGK QTSDESNYHL TFDAVTLKNQ NGYYCKAACG DVYEERRISL YIYYLPRTLR
     LEPSGPVWAG EQVSLICHVD MVYPIEDLKV EYFKGTELLE TISSDRLSLP ESSQSINHQL
     TPAMEDHGKN LSCVAYLKIG KEVESAQGSF ILDVHYGPLN ITLNRAAIST ATKGQDITVT
     CSTQSNPPAN ISWSKLWPEG WLPVSAQEAT LKLYDVGFSD SGTYRCEASN GPRKETKELQ
     IQIEGAPSGT RLSITPSVAK QGENVTIACT TSSYPLAQFV LRQSGSSLPK LPSSDGTFTI
     TSVQSANAGQ YECEATNSLG KDTASEKLSV QDGPLNITLN RAAISTATKG QDITVTCSTQ
     SNPPANISWS KLWPEGWLPV SAQEATLKLY DVGFSDSGTY RCEASNGPRK ETKELQIQIE
     GAPSGTRLSI TPSVAKQGEN VTIACTTSSY PLAQFVLRQS GSSLPKLPSS DGTFTITSVQ
     SANAGQYECE ATNSLGKDTA SEKLSVQVPP QNLLVVVSPS STFREGYNLT FNCTADSSSP
     THYTWTKLGN ESMLSLSNSF TLWNARAYHA GVYQVEVRNE LGSMTGTVEI IIKGERTDEG
     PELGSLGTYL MVGGMALAGG GLVTGLWWFR KKMLADSFSP VSGQIP
//