ID V9KGT1_CALMI Unreviewed; 502 AA.
AC V9KGT1;
DT 19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT 19-MAR-2014, sequence version 1.
DT 22-FEB-2023, entry version 14.
DE SubName: Full=B-cell linker protein {ECO:0000313|EMBL:AFO97051.1};
OS Callorhinchus milii (Ghost shark).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Chondrichthyes;
OC Holocephali; Chimaeriformes; Callorhinchidae; Callorhinchus.
OX NCBI_TaxID=7868 {ECO:0000313|EMBL:AFO97051.1};
RN [1] {ECO:0000313|EMBL:AFO97051.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Intestine {ECO:0000313|EMBL:AFO97051.1};
RX PubMed=24402279; DOI=10.1038/nature12826;
RG International Elephant Shark Genome Sequencing Consortium;
RA Venkatesh B., Lee A.P., Ravi V., Maurya A.K., Lian M.M., Swann J.B.,
RA Ohta Y., Flajnik M.F., Sutoh Y., Kasahara M., Hoon S., Gangu V., Roy S.W.,
RA Irimia M., Korzh V., Kondrychyn I., Lim Z.W., Tay B.H., Tohari S.,
RA Kong K.W., Ho S., Lorente-Galdos B., Quilez J., Marques-Bonet T.,
RA Raney B.J., Ingham P.W., Tay A., Hillier L.W., Minx P., Boehm T.,
RA Wilson R.K., Brenner S., Warren W.C.;
RT "Elephant shark genome provides unique insights into gnathostome
RT evolution.";
RL Nature 505:174-179(2014).
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DR EMBL; JW864534; AFO97051.1; -; mRNA.
DR AlphaFoldDB; V9KGT1; -.
DR CDD; cd09929; SH2_BLNK_SLP-76; 1.
DR Gene3D; 3.30.505.10; SH2 domain; 1.
DR InterPro; IPR000980; SH2.
DR InterPro; IPR036860; SH2_dom_sf.
DR PANTHER; PTHR14098:SF3; B-CELL LINKER PROTEIN; 1.
DR PANTHER; PTHR14098; SH2 DOMAIN CONTAINING PROTEIN; 1.
DR Pfam; PF00017; SH2; 1.
DR SMART; SM00252; SH2; 1.
DR SUPFAM; SSF55550; SH2 domain; 1.
DR PROSITE; PS50001; SH2; 1.
PE 2: Evidence at transcript level;
KW SH2 domain {ECO:0000256|PROSITE-ProRule:PRU00191}.
FT DOMAIN 392..499
FT /note="SH2"
FT /evidence="ECO:0000259|PROSITE:PS50001"
FT REGION 50..391
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 83..99
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 193..208
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 211..228
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 295..316
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 362..376
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 377..391
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 502 AA; 55912 MW; DFEFA26706482798 CRC64;
MFLNSSDGHQ NRFNSLEYPQ IQKIVQDIKK NDGGIIRKFK KFHTQQAALI RKTGKNTWDR
FTRPAPPNVP QRDYSNPGAE EAEGQWSEDE FDNSDYENPD ENSDGSVTYE APGEDDENYE
PPPSENKTKI VSRPLTSTKS EYADHRPGSS KAAAISRPGP ILPKPANYSP KLLCSPPRPA
PRKGKREDDE DDYIVPVENN DPDEAYIDPT ETDPSLSTKR QAAQPCSESP PGNDVYEIPD
TEETPQPAQR VKPQLPKPVP KGAGNPSLFL RTFPKLTVAS ERKGSLMNSK APSASHDVDS
EDYEVCDPES NEKPEIPGKP TRFSNPSAEA PILPARPFDK KPQALRLPPI NKSNAPELPS
RPIGTLPRPN VPPRPLSPSS IEQDSSVNGK PWYTNYGDRK AAEEALNKSN KDGSFLIRKS
SGQDSKQPYT LVVLYKRRVY NIPVRYVEAT KEYALGRKKS GEDRFASVAE IIENHQRNAL
VLIDSQNNTK DSTKLKHPVK IS
//
