ID V9KHS9_CALMI Unreviewed; 768 AA.
AC V9KHS9;
DT 19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT 19-MAR-2014, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE SubName: Full=Tudor domain-containing protein 5 {ECO:0000313|EMBL:AFO97522.1};
DE Flags: Fragment;
OS Callorhinchus milii (Ghost shark).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Chondrichthyes;
OC Holocephali; Chimaeriformes; Callorhinchidae; Callorhinchus.
OX NCBI_TaxID=7868 {ECO:0000313|EMBL:AFO97522.1};
RN [1] {ECO:0000313|EMBL:AFO97522.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Ovary {ECO:0000313|EMBL:AFO97522.1};
RX PubMed=24402279; DOI=10.1038/nature12826;
RG International Elephant Shark Genome Sequencing Consortium;
RA Venkatesh B., Lee A.P., Ravi V., Maurya A.K., Lian M.M., Swann J.B.,
RA Ohta Y., Flajnik M.F., Sutoh Y., Kasahara M., Hoon S., Gangu V., Roy S.W.,
RA Irimia M., Korzh V., Kondrychyn I., Lim Z.W., Tay B.H., Tohari S.,
RA Kong K.W., Ho S., Lorente-Galdos B., Quilez J., Marques-Bonet T.,
RA Raney B.J., Ingham P.W., Tay A., Hillier L.W., Minx P., Boehm T.,
RA Wilson R.K., Brenner S., Warren W.C.;
RT "Elephant shark genome provides unique insights into gnathostome
RT evolution.";
RL Nature 505:174-179(2014).
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
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DR EMBL; JW865005; AFO97522.1; -; mRNA.
DR AlphaFoldDB; V9KHS9; -.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0030154; P:cell differentiation; IEA:UniProt.
DR CDD; cd20419; Tudor_TDRD5; 1.
DR Gene3D; 2.30.30.140; -; 1.
DR Gene3D; 2.40.50.90; -; 1.
DR Gene3D; 3.30.420.610; LOTUS domain-like; 3.
DR InterPro; IPR041966; LOTUS-like.
DR InterPro; IPR025605; OST-HTH/LOTUS_dom.
DR InterPro; IPR035437; SNase_OB-fold_sf.
DR InterPro; IPR002999; Tudor.
DR PANTHER; PTHR22948; TUDOR DOMAIN CONTAINING PROTEIN; 1.
DR PANTHER; PTHR22948:SF80; TUDOR DOMAIN-CONTAINING PROTEIN 5; 1.
DR Pfam; PF12872; OST-HTH; 3.
DR Pfam; PF00567; TUDOR; 1.
DR SMART; SM00333; TUDOR; 1.
DR SUPFAM; SSF63748; Tudor/PWWP/MBT; 1.
DR PROSITE; PS51644; HTH_OST; 3.
DR PROSITE; PS50304; TUDOR; 1.
PE 2: Evidence at transcript level;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490}.
FT DOMAIN 7..80
FT /note="HTH OST-type"
FT /evidence="ECO:0000259|PROSITE:PS51644"
FT DOMAIN 128..202
FT /note="HTH OST-type"
FT /evidence="ECO:0000259|PROSITE:PS51644"
FT DOMAIN 288..362
FT /note="HTH OST-type"
FT /evidence="ECO:0000259|PROSITE:PS51644"
FT DOMAIN 490..549
FT /note="Tudor"
FT /evidence="ECO:0000259|PROSITE:PS50304"
FT REGION 651..697
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 651..689
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 768
FT /evidence="ECO:0000313|EMBL:AFO97522.1"
SQ SEQUENCE 768 AA; 87147 MW; 66C84670DC40641A CRC64;
MSDQEVLLDV LKKELRSLLI SAQGGLSPVE LESDYYKMMG KRLPLYALGY RSVLELITDM
PDAIKIHTCG NGSLILKGNG DATTKGIEEM VAKSRIPSKT KRNLRKPRYD FTQKQGFLPR
RCNSIPVLPA LVKCEIRELL LSFPDGILLS DFDKAFVKKY GRPFQCARYG FYSLQEVLKT
AADDIVIQQT RRGSLLLLKV QNRECFFVQG EWHCQSIANH PVEAESTSVP LIPLKPPTQT
FQKQSLEPLD PDNVPGSNTG LEYFDGGMKK LVKDLKAVLL EKGVGGTIDP KVKEKVWFTV
AQRPDGLLAS RLPVEFKDIF GQELPLKELG FYSVTELVAA LSDIFYVERD VKNQDWLIFD
IKRHQSLQKQ VELQLKDKLS SPDWNHGRLS DSQQNEMNMV EMVTKILYLP DPEFEIPPDA
MQDGNLYRTP ELEGNSFVSV FVESVVSPSQ FYVRFYGKDA SEMLEDLMIG MRRCYSYEEV
SERYVMPDFF IRQGQVCCVR NPNDVWWYRV VIHQLLDADQ VEVFYVDFGD ISSVERSRLR
FLKCCHSKFP AQAIPSKLMW VQPVKNEWST PAKMLFLRFC RKQPLVALIC MYIRDVLHLF
LCDTSTEEDV YINDVLKKAG HAVPCLPDNT TKGFGELNPA ALYLKLKPPS AKELPSRKEE
SATAPHEKES KDISEDDPKL DHPAHGGKNE QDFDPLTSDL PYLEPYQACT VSSNEGYPSE
FSVKQSAMEI SEEPGDVEFC SSVVGAQVSQ ARDLGLIPGR TKPWASFL
//
