ID V9KP76_CALMI Unreviewed; 497 AA.
AC V9KP76;
DT 19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT 19-MAR-2014, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE SubName: Full=Butyrophilin, subfamily 2, member A2 {ECO:0000313|EMBL:AFP00083.1};
DE Flags: Fragment;
OS Callorhinchus milii (Ghost shark).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Chondrichthyes;
OC Holocephali; Chimaeriformes; Callorhinchidae; Callorhinchus.
OX NCBI_TaxID=7868 {ECO:0000313|EMBL:AFP00083.1};
RN [1] {ECO:0000313|EMBL:AFP00083.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Liver {ECO:0000313|EMBL:AFP00083.1};
RX PubMed=24402279; DOI=10.1038/nature12826;
RG International Elephant Shark Genome Sequencing Consortium;
RA Venkatesh B., Lee A.P., Ravi V., Maurya A.K., Lian M.M., Swann J.B.,
RA Ohta Y., Flajnik M.F., Sutoh Y., Kasahara M., Hoon S., Gangu V., Roy S.W.,
RA Irimia M., Korzh V., Kondrychyn I., Lim Z.W., Tay B.H., Tohari S.,
RA Kong K.W., Ho S., Lorente-Galdos B., Quilez J., Marques-Bonet T.,
RA Raney B.J., Ingham P.W., Tay A., Hillier L.W., Minx P., Boehm T.,
RA Wilson R.K., Brenner S., Warren W.C.;
RT "Elephant shark genome provides unique insights into gnathostome
RT evolution.";
RL Nature 505:174-179(2014).
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DR EMBL; JW867565; AFP00083.1; -; mRNA.
DR AlphaFoldDB; V9KP76; -.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd13733; SPRY_PRY_C-I_1; 1.
DR Gene3D; 2.60.120.920; -; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 2.
DR InterPro; IPR001870; B30.2/SPRY.
DR InterPro; IPR043136; B30.2/SPRY_sf.
DR InterPro; IPR003879; Butyrophylin_SPRY.
DR InterPro; IPR013162; CD80_C2-set.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR006574; PRY.
DR InterPro; IPR003877; SPRY_dom.
DR PANTHER; PTHR24100; BUTYROPHILIN; 1.
DR PANTHER; PTHR24100:SF145; BUTYROPHILIN SUBFAMILY 1 MEMBER A1; 1.
DR Pfam; PF08205; C2-set_2; 1.
DR Pfam; PF13765; PRY; 1.
DR Pfam; PF00622; SPRY; 1.
DR PRINTS; PR01407; BUTYPHLNCDUF.
DR SMART; SM00589; PRY; 1.
DR SMART; SM00449; SPRY; 1.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
DR SUPFAM; SSF48726; Immunoglobulin; 2.
DR PROSITE; PS50188; B302_SPRY; 1.
DR PROSITE; PS50835; IG_LIKE; 1.
PE 2: Evidence at transcript level;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 182..205
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 83..172
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 304..496
FT /note="B30.2/SPRY"
FT /evidence="ECO:0000259|PROSITE:PS50188"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:AFP00083.1"
SQ SEQUENCE 497 AA; 55645 MW; 4DE164A207A0B06C CRC64;
TPRLPYETPV HLHRGGSDVL AGQSPEYAGR TAIFHRELAR GNVSLRLQDV RVSDQGSYKC
FVSTESRDEE ALVSLDVAST GQEPVMSLES QSGSGIRLSC SSGGWFPNPG VSWLRGDGAN
VTAKAETRWQ VEPDGRVAVR SRVEVTPAEG KSFTCRISNR RLHSARESRL LVNDDFFPRV
SAWMAGFLVM VLLALAIVGL GAFAYRRVTK TLEGYKQSTS LKHVTALETT IELQKESAEE
VKMNWTKDID RIKQISQSDH EALRKAFDEE RKAFGAEREK MNAEFERERQ TAKAEYQKLR
IEYEQWKPLV ISEWERIQSH AVRVTLDGRT AFAGLEVSED GLSVRGLETP RTEENGPECF
DMSPYVLGSN AFETGRHYWE VDVANKSFWD LGVARESAPR KGSLRLTAEA GFWVLGRSGD
GYEVSEAAQG SVTLTDKPRL IGVWLDCEAG EVAFYNAEGM YHLFTFRAQV LGRVRPFFWP
GWDSELMAIC PPKGLVD
//
