ID V9KRI1_CALMI Unreviewed; 519 AA.
AC V9KRI1;
DT 19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT 19-MAR-2014, sequence version 1.
DT 27-MAR-2024, entry version 44.
DE SubName: Full=E3 ubiquitin-protein ligase TRIM56-like protein {ECO:0000313|EMBL:AFP01344.1};
DE Flags: Fragment;
OS Callorhinchus milii (Ghost shark).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Chondrichthyes;
OC Holocephali; Chimaeriformes; Callorhinchidae; Callorhinchus.
OX NCBI_TaxID=7868 {ECO:0000313|EMBL:AFP01344.1};
RN [1] {ECO:0000313|EMBL:AFP01344.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Spleen {ECO:0000313|EMBL:AFP01344.1};
RX PubMed=24402279; DOI=10.1038/nature12826;
RG International Elephant Shark Genome Sequencing Consortium;
RA Venkatesh B., Lee A.P., Ravi V., Maurya A.K., Lian M.M., Swann J.B.,
RA Ohta Y., Flajnik M.F., Sutoh Y., Kasahara M., Hoon S., Gangu V., Roy S.W.,
RA Irimia M., Korzh V., Kondrychyn I., Lim Z.W., Tay B.H., Tohari S.,
RA Kong K.W., Ho S., Lorente-Galdos B., Quilez J., Marques-Bonet T.,
RA Raney B.J., Ingham P.W., Tay A., Hillier L.W., Minx P., Boehm T.,
RA Wilson R.K., Brenner S., Warren W.C.;
RT "Elephant shark genome provides unique insights into gnathostome
RT evolution.";
RL Nature 505:174-179(2014).
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
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DR EMBL; JW868826; AFP01344.1; -; mRNA.
DR AlphaFoldDB; V9KRI1; -.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR Gene3D; 4.10.830.40; -; 1.
DR Gene3D; 3.30.160.60; Classic Zinc Finger; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR047153; TRIM45/56/19.
DR InterPro; IPR027370; Znf-RING_euk.
DR InterPro; IPR000315; Znf_B-box.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR InterPro; IPR017907; Znf_RING_CS.
DR PANTHER; PTHR25462; BONUS, ISOFORM C-RELATED; 1.
DR PANTHER; PTHR25462:SF304; E3 UBIQUITIN-PROTEIN LIGASE TRIM56; 1.
DR Pfam; PF00643; zf-B_box; 1.
DR Pfam; PF13445; zf-RING_UBOX; 1.
DR SMART; SM00336; BBOX; 2.
DR SMART; SM00184; RING; 1.
DR SUPFAM; SSF57845; B-box zinc-binding domain; 1.
DR SUPFAM; SSF101898; NHL repeat; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR PROSITE; PS50119; ZF_BBOX; 1.
DR PROSITE; PS00518; ZF_RING_1; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 2: Evidence at transcript level;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00024}.
FT DOMAIN 18..59
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT DOMAIN 153..194
FT /note="B box-type"
FT /evidence="ECO:0000259|PROSITE:PS50119"
FT COILED 216..246
FT /evidence="ECO:0000256|SAM:Coils"
FT NON_TER 519
FT /evidence="ECO:0000313|EMBL:AFP01344.1"
SQ SEQUENCE 519 AA; 58487 MW; 86C452D4765F7DB0 CRC64;
MATSSSFAEI IKKDFLNCKL CFEKYYNPKA LPCLHTYCEE CLRKLVPHKT KVFQCPECRE
EVILSKGGIS NLRTNFYIND LLNALQLNEK IDKMCNVCPP KWRHDRPAVT ECLDCPSFMC
QLCTDDHLSI PSQHQHKVLR LSDTSCDAEI HVRKKIYCAA HPKKEGGYFC RPCNASICDT
CLVNSHSRHE ALSMSKAAES STPAVRELVG KLSTKVQSLT RSQDDLNAAL EKLKAAERSI
ESKMVDAVAQ VQSALFKQRD DIRKKMSDFV KQQEALYETA KADLQRQTKS AESTRDYSER
VLRAGQNGSI VCLEKILGEQ VRTLLAYQPP SMKEDIPKLV VTKDYMSQMD LFRIELGQEA
AMQKIPPVPD QAPEHWQEFA RFSSPELPPV QSPYENVAGN WLRPARRCNF TTECYAECNS
KLTGVSMLNN GDIIVADEAN GILKCYSIDG DFRRQIAIGD TGKDPCSVAV CGDLIACTAE
SKLYFLDYDG DRVRQLLLRG SESSYPITAY EDQYVVVSE
//
