ID V9KWE5_CALMI Unreviewed; 388 AA.
AC V9KWE5;
DT 19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT 19-MAR-2014, sequence version 1.
DT 27-MAR-2024, entry version 49.
DE SubName: Full=DNA/RNA-binding protein KIN17-like protein {ECO:0000313|EMBL:AFP03047.1};
DE SubName: Full=Kin17 DNA and RNA binding protein {ECO:0000313|Ensembl:ENSCMIP00000029865.1};
GN Name=kin {ECO:0000313|Ensembl:ENSCMIP00000029865.1};
OS Callorhinchus milii (Ghost shark).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Chondrichthyes;
OC Holocephali; Chimaeriformes; Callorhinchidae; Callorhinchus.
OX NCBI_TaxID=7868 {ECO:0000313|EMBL:AFP03047.1};
RN [1] {ECO:0000313|Proteomes:UP000314986}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=17185593; DOI=10.1126/science.1130708;
RA Venkatesh B., Kirkness E.F., Loh Y.H., Halpern A.L., Lee A.P., Johnson J.,
RA Dandona N., Viswanathan L.D., Tay A., Venter J.C., Strausberg R.L.,
RA Brenner S.;
RT "Ancient noncoding elements conserved in the human genome.";
RL Science 314:1892-1892(2006).
RN [2] {ECO:0000313|Proteomes:UP000314986}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=17407382;
RA Venkatesh B., Kirkness E.F., Loh Y.H., Halpern A.L., Lee A.P., Johnson J.,
RA Dandona N., Viswanathan L.D., Tay A., Venter J.C., Strausberg R.L.,
RA Brenner S.;
RT "Survey sequencing and comparative analysis of the elephant shark
RT (Callorhinchus milii) genome.";
RL PLoS Biol. 5:E101-E101(2007).
RN [3] {ECO:0000313|EMBL:AFP03047.1, ECO:0000313|Proteomes:UP000314986}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Ovary {ECO:0000313|EMBL:AFP03047.1};
RX PubMed=24402279; DOI=10.1038/nature12826;
RG International Elephant Shark Genome Sequencing Consortium;
RA Venkatesh B., Lee A.P., Ravi V., Maurya A.K., Lian M.M., Swann J.B.,
RA Ohta Y., Flajnik M.F., Sutoh Y., Kasahara M., Hoon S., Gangu V., Roy S.W.,
RA Irimia M., Korzh V., Kondrychyn I., Lim Z.W., Tay B.H., Tohari S.,
RA Kong K.W., Ho S., Lorente-Galdos B., Quilez J., Marques-Bonet T.,
RA Raney B.J., Ingham P.W., Tay A., Hillier L.W., Minx P., Boehm T.,
RA Wilson R.K., Brenner S., Warren W.C.;
RT "Elephant shark genome provides unique insights into gnathostome
RT evolution.";
RL Nature 505:174-179(2014).
RN [4] {ECO:0000313|Ensembl:ENSCMIP00000029865.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the KIN17 family.
CC {ECO:0000256|ARBA:ARBA00008517}.
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DR EMBL; JW870529; AFP03047.1; -; mRNA.
DR RefSeq; XP_007905842.1; XM_007907651.1.
DR STRING; 7868.ENSCMIP00000029865; -.
DR Ensembl; ENSCMIT00000030331.1; ENSCMIP00000029865.1; ENSCMIG00000012896.1.
DR GeneID; 103187926; -.
DR KEGG; cmk:103187926; -.
DR CTD; 22944; -.
DR GeneTree; ENSGT00390000005903; -.
DR OMA; RMTDFIE; -.
DR OrthoDB; 103614at2759; -.
DR Proteomes; UP000314986; Unassembled WGS sequence.
DR CDD; cd13155; KOW_KIN17; 1.
DR Gene3D; 2.30.30.140; -; 1.
DR Gene3D; 2.30.30.30; -; 1.
DR Gene3D; 1.10.10.2030; DNA/RNA-binding protein Kin17, conserved domain; 1.
DR InterPro; IPR019447; DNA/RNA-bd_Kin17_WH-like_dom.
DR InterPro; IPR037321; KIN17-like.
DR InterPro; IPR038254; KIN17_WH-like_sf.
DR InterPro; IPR041330; KN17_SH3.
DR InterPro; IPR041995; KOW_KIN17.
DR InterPro; IPR014722; Rib_uL2_dom2.
DR InterPro; IPR036236; Znf_C2H2_sf.
DR PANTHER; PTHR12805:SF0; DNA_RNA-BINDING PROTEIN KIN17; 1.
DR PANTHER; PTHR12805; KIN17 KIN, ANTIGENIC DETERMINANT OF RECA PROTEIN HOMOLOG; 1.
DR Pfam; PF10357; Kin17_mid; 1.
DR Pfam; PF18131; KN17_SH3; 1.
DR SMART; SM01253; Kin17_mid; 1.
DR SUPFAM; SSF57667; beta-beta-alpha zinc fingers; 1.
PE 2: Evidence at transcript level;
KW Reference proteome {ECO:0000313|Proteomes:UP000314986}.
FT DOMAIN 52..178
FT /note="DNA/RNA-binding protein Kin17 WH-like"
FT /evidence="ECO:0000259|SMART:SM01253"
FT REGION 203..254
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 205..221
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 239..254
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 388 AA; 45239 MW; D7A89546183715F3 CRC64;
MGKAEFLTPK AIANRIKSKG LQKLRWYCQM CQKQCRDENG FKCHCMSESH QRQLLLASEN
PQQFMDYFSE EFRTEFLELL RRRFGTKRVH NNVIYNEYIS HREHVHMNST MWETLTDFTK
WLGREGHCKV DETPKGWYIQ YIDRDPETIC RQQELEKKKK QELDDQERNA KFIEELVRRG
KEGKEEEAPV FTELKRENEE EKVTFNLNKG PSTSAATTAP KPGTLRPSAL QAAASVKRKE
PSHTSDTKDK KKKSALDEIM EFEEQKKRSL RRDYWLHTGI VVKLITKKLG EKYYKKKALI
KEVQEKYTAV IKMIDSGDKL KVDQTHLETV IPVPGKKVLV VNGGYRGHEA ILDCIDEKKY
CATIIIDSGP LQGRKVDSVQ YEDISKLA
//
