ID V9KWJ4_CALMI Unreviewed; 380 AA.
AC V9KWJ4;
DT 19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT 19-MAR-2014, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE RecName: Full=26S proteasome non-ATPase regulatory subunit 4 {ECO:0000256|ARBA:ARBA00014934};
DE AltName: Full=26S proteasome regulatory subunit RPN10 {ECO:0000256|ARBA:ARBA00044341};
OS Callorhinchus milii (Ghost shark).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Chondrichthyes;
OC Holocephali; Chimaeriformes; Callorhinchidae; Callorhinchus.
OX NCBI_TaxID=7868 {ECO:0000313|EMBL:AFP03053.1};
RN [1] {ECO:0000313|EMBL:AFP03053.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Testis {ECO:0000313|EMBL:AFP03053.1};
RX PubMed=24402279; DOI=10.1038/nature12826;
RG International Elephant Shark Genome Sequencing Consortium;
RA Venkatesh B., Lee A.P., Ravi V., Maurya A.K., Lian M.M., Swann J.B.,
RA Ohta Y., Flajnik M.F., Sutoh Y., Kasahara M., Hoon S., Gangu V., Roy S.W.,
RA Irimia M., Korzh V., Kondrychyn I., Lim Z.W., Tay B.H., Tohari S.,
RA Kong K.W., Ho S., Lorente-Galdos B., Quilez J., Marques-Bonet T.,
RA Raney B.J., Ingham P.W., Tay A., Hillier L.W., Minx P., Boehm T.,
RA Wilson R.K., Brenner S., Warren W.C.;
RT "Elephant shark genome provides unique insights into gnathostome
RT evolution.";
RL Nature 505:174-179(2014).
CC -!- SIMILARITY: Belongs to the proteasome subunit S5A family.
CC {ECO:0000256|ARBA:ARBA00005574}.
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DR EMBL; JW870535; AFP03053.1; -; mRNA.
DR AlphaFoldDB; V9KWJ4; -.
DR GO; GO:0000502; C:proteasome complex; IEA:UniProtKB-KW.
DR CDD; cd22297; PSMD4_RAZUL; 1.
DR CDD; cd01452; VWA_26S_proteasome_subunit; 1.
DR Gene3D; 6.10.250.380; -; 1.
DR Gene3D; 6.10.300.40; -; 1.
DR Gene3D; 3.40.50.410; von Willebrand factor, type A domain; 1.
DR InterPro; IPR049590; PSMD4_RAZUL-like.
DR InterPro; IPR003903; UIM_dom.
DR InterPro; IPR002035; VWF_A.
DR InterPro; IPR036465; vWFA_dom_sf.
DR PANTHER; PTHR10223; 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 4; 1.
DR PANTHER; PTHR10223:SF0; 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 4; 1.
DR Pfam; PF02809; UIM; 2.
DR Pfam; PF13519; VWA_2; 1.
DR SMART; SM00726; UIM; 2.
DR SMART; SM00327; VWA; 1.
DR SUPFAM; SSF53300; vWA-like; 1.
DR PROSITE; PS50330; UIM; 2.
DR PROSITE; PS50234; VWFA; 1.
PE 2: Evidence at transcript level;
KW Proteasome {ECO:0000256|ARBA:ARBA00022942, ECO:0000313|EMBL:AFP03053.1}.
FT DOMAIN 5..188
FT /note="VWFA"
FT /evidence="ECO:0000259|PROSITE:PS50234"
FT REGION 225..255
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 315..380
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 225..239
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 366..380
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 380 AA; 41038 MW; 9CE77C797FA6BACD CRC64;
MVLESTMVCV DNSEYMRNGD FLPTRLQAQQ DAVNIVCHSK TRTNPENNVG LITLANNCEV
LTTLTPDTGR ILSKLHAVQP TGKISFCTGI RVAHLALKHR QGKNHKMRII VFVGSPIDDN
EKDLVKLAKR LKKEKVNVDI VNFGEEEANT EKLTAFVNAL NGKEGTGSHL VTVPPGPSLA
DALISSPILA GEGGAMLGLG ASDFEFGVDP SADPELALAL RVSMEEQRQR QEEEARRAAA
ASAAEAGIVT PTGDDTDEAL LKMSISQTES TGKGVPDINS MTEEEQIAYA MQMSLQAPEL
ESQGDTSDLD TATAMDTSEA SGKDEDDYDV MQDPEFLQSV LENLPGVDPN NEAIRNAMGS
LSSQPPSKKD EDKKKEEERK
//
