ID V9M9C1_GADMO Unreviewed; 246 AA.
AC V9M9C1;
DT 19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT 19-MAR-2014, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE RecName: Full=Inhibin alpha chain {ECO:0000256|ARBA:ARBA00019280};
DE Flags: Fragment;
OS Gadus morhua (Atlantic cod).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Zeiogadaria; Gadariae; Gadiformes; Gadoidei; Gadidae; Gadus.
OX NCBI_TaxID=8049 {ECO:0000313|EMBL:AGE15748.1};
RN [1] {ECO:0000313|EMBL:AGE15748.1}
RP NUCLEOTIDE SEQUENCE.
RA Lazado C.C., Kumaratunga H., Nagasawa K., Fernandes J.M.O.;
RT "Molecular cloning and characterization of gonadal somatic cell marker
RT genes in Atlantic cod, Gadus morhua.";
RL Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBUNIT: Dimeric, linked by one or more disulfide bonds. Inhibin A is a
CC dimer of alpha and beta-A. Inhibin B is a dimer of alpha and beta-B.
CC {ECO:0000256|ARBA:ARBA00011767}.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613}.
CC -!- SIMILARITY: Belongs to the TGF-beta family.
CC {ECO:0000256|ARBA:ARBA00006656, ECO:0000256|RuleBase:RU000354}.
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DR EMBL; KC204830; AGE15748.1; -; mRNA.
DR AlphaFoldDB; V9M9C1; -.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
DR GO; GO:0008083; F:growth factor activity; IEA:UniProtKB-KW.
DR Gene3D; 2.10.90.10; Cystine-knot cytokines; 1.
DR InterPro; IPR029034; Cystine-knot_cytokine.
DR InterPro; IPR001839; TGF-b_C.
DR InterPro; IPR015615; TGF-beta-rel.
DR PANTHER; PTHR11848:SF117; INHIBIN ALPHA CHAIN; 1.
DR PANTHER; PTHR11848; TGF-BETA FAMILY; 1.
DR Pfam; PF00019; TGF_beta; 1.
DR PRINTS; PR00669; INHIBINA.
DR SMART; SM00204; TGFB; 1.
DR SUPFAM; SSF57501; Cystine-knot cytokines; 1.
DR PROSITE; PS51362; TGF_BETA_2; 1.
PE 2: Evidence at transcript level;
KW Growth factor {ECO:0000256|ARBA:ARBA00023030,
KW ECO:0000256|RuleBase:RU000354}; Secreted {ECO:0000256|ARBA:ARBA00022525}.
FT DOMAIN 130..246
FT /note="TGF-beta family profile"
FT /evidence="ECO:0000259|PROSITE:PS51362"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:AGE15748.1"
SQ SEQUENCE 246 AA; 27582 MW; C23778A5C80F6AEE CRC64;
ADSPCGRTEV RDAETATFHS YHFQPSVNPQ ELLITSAHFW FYAGPESNSS SPLYILNSGQ
HPDHLAAVAL ALTSSDGWAT YDLDDHHRPA KVYSGPLTLQ VRSTNRLPLI EDPDKTPFLH
LRARRRVSGR WPRHAIPWSQ SAADLLQRPS QQQPESRDCW RDAVEISFDE LGWGNWIVHP
KVVTFSYCHG NCSAPDRGTA LLGIKQCCAP VPESMRSLRI TTTSDGGYSF MYETLPNIIP
EECSCF
//
