ID   V9VG22_BIOGL            Unreviewed;       144 AA.
AC   V9VG22;
DT   19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT   19-MAR-2014, sequence version 1.
DT   27-MAR-2024, entry version 23.
DE   SubName: Full=Insulin-induced 2 protein-like isoform {ECO:0000313|EMBL:AHC95480.1};
DE   Flags: Fragment;
OS   Biomphalaria glabrata (Bloodfluke planorb) (Freshwater snail).
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Gastropoda;
OC   Heterobranchia; Euthyneura; Panpulmonata; Hygrophila; Lymnaeoidea;
OC   Planorbidae; Biomphalaria.
OX   NCBI_TaxID=6526 {ECO:0000313|EMBL:AHC95480.1};
RN   [1] {ECO:0000313|EMBL:AHC95480.1}
RP   NUCLEOTIDE SEQUENCE.
RA   Wu X.-J., Humphries J.E., Dinguirard N., Chung C.-Y., Yoshino T.P.;
RT   "Differentially expressed gene transcripts from LTP (larval transformation
RT   protein) treated Biomphalaria glabrata embryonic cell line identified by
RT   subtractive hybridization.";
RL   Submitted (SEP-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane
CC       {ECO:0000256|ARBA:ARBA00004477}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004477}. Membrane
CC       {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the INSIG family.
CC       {ECO:0000256|ARBA:ARBA00007475}.
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DR   EMBL; KF715666; AHC95480.1; -; mRNA.
DR   AlphaFoldDB; V9VG22; -.
DR   VEuPathDB; VectorBase:BGLB012519; -.
DR   GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0008203; P:cholesterol metabolic process; IEA:UniProtKB-KW.
DR   InterPro; IPR025929; INSIG_fam.
DR   PANTHER; PTHR15301:SF12; INSILUN INDUCED PROTEIN; 1.
DR   PANTHER; PTHR15301; INSULIN-INDUCED GENE 1; 1.
DR   Pfam; PF07281; INSIG; 1.
PE   2: Evidence at transcript level;
KW   Cholesterol metabolism {ECO:0000256|ARBA:ARBA00022548};
KW   Endoplasmic reticulum {ECO:0000256|ARBA:ARBA00022824};
KW   Lipid metabolism {ECO:0000256|ARBA:ARBA00023166};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Steroid metabolism {ECO:0000256|ARBA:ARBA00023166};
KW   Sterol metabolism {ECO:0000256|ARBA:ARBA00023166};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        49..66
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        73..92
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        104..124
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:AHC95480.1"
SQ   SEQUENCE   144 AA;  16154 MW;  28E09B050BB41DBC CRC64;
     VIGLLYPCLD KQLGEELRYK REWSSVMRCV AVFVGINHAS AKIDFANNIQ LSVSLAAMSI
     GLWWLFDRSR SGFGLGVGIA VLATFVTQLL VYNDVYRYTE PDFLFVRSWL PCVFFSGGVT
     MGNIGRQLAS YDNDPSNDAR IKKD
//