ID V9WV72_9PSED Unreviewed; 297 AA.
AC V9WV72;
DT 19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT 19-MAR-2014, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE SubName: Full=Dihydrodipicolinate synthase {ECO:0000313|EMBL:AHD13615.1};
GN ORFNames=C163_07745 {ECO:0000313|EMBL:AHD13615.1};
OS Pseudomonas sp. FGI182.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Pseudomonadales;
OC Pseudomonadaceae; Pseudomonas.
OX NCBI_TaxID=1259844 {ECO:0000313|EMBL:AHD13615.1, ECO:0000313|Proteomes:UP000018783};
RN [1] {ECO:0000313|EMBL:AHD13615.1, ECO:0000313|Proteomes:UP000018783}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=FGI182 {ECO:0000313|EMBL:AHD13615.1,
RC ECO:0000313|Proteomes:UP000018783};
RG DOE Joint Genome Institute;
RA Currie C., Huntemann M., Han J., Chen A., Kyrpides N., Mavromatis K.,
RA Markowitz V., Palaniappan K., Ivanova N., Schaumberg A., Pati A.,
RA Liolios K., Nordberg H.P., Cantor M.N., Hua S.X., Woyke T.;
RL Submitted (DEC-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the DapA family.
CC {ECO:0000256|PIRNR:PIRNR001365}.
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DR EMBL; CP007012; AHD13615.1; -; Genomic_DNA.
DR RefSeq; WP_025338272.1; NZ_CP007012.1.
DR AlphaFoldDB; V9WV72; -.
DR PATRIC; fig|1259844.3.peg.1494; -.
DR HOGENOM; CLU_049343_5_0_6; -.
DR Proteomes; UP000018783; Chromosome.
DR GO; GO:0016829; F:lyase activity; IEA:UniProtKB-KW.
DR CDD; cd00408; DHDPS-like; 1.
DR Gene3D; 3.20.20.70; Aldolase class I; 1.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR002220; DapA-like.
DR PANTHER; PTHR12128:SF73; 4-HYDROXY-TETRAHYDRODIPICOLINATE SYNTHASE; 1.
DR PANTHER; PTHR12128; DIHYDRODIPICOLINATE SYNTHASE; 1.
DR Pfam; PF00701; DHDPS; 1.
DR PIRSF; PIRSF001365; DHDPS; 1.
DR PRINTS; PR00146; DHPICSNTHASE.
DR SMART; SM01130; DHDPS; 1.
DR SUPFAM; SSF51569; Aldolase; 1.
PE 3: Inferred from homology;
KW Lyase {ECO:0000256|ARBA:ARBA00023239, ECO:0000256|PIRNR:PIRNR001365}.
FT ACT_SITE 137
FT /note="Proton donor/acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR001365-1"
FT ACT_SITE 166
FT /note="Schiff-base intermediate with substrate"
FT /evidence="ECO:0000256|PIRSR:PIRSR001365-1"
FT BINDING 49
FT /ligand="pyruvate"
FT /ligand_id="ChEBI:CHEBI:15361"
FT /evidence="ECO:0000256|PIRSR:PIRSR001365-2"
SQ SEQUENCE 297 AA; 31653 MW; B59FD13049DA3CDF CRC64;
MSTPVIRGVI GYTITPFTAD GALDLDALGL SIDRLIEDGV HAIAPLGSTG EGAYLSDSEW
ETVVRFSLAR IAGRVPSVVS VSDLTTARTV QRARLAQACG ATAVMVLPIS YWKLTEAEVV
AHYKAVGAAI DIPIMLYNNP GTSGTDLSVE LILRILGEVP NVTMVKESTG DIQRMHRLFK
ATDGQVAFYN GCNPLTLEAL VAGATGWCTA APNLIPALNL ALWDAVQQGD LAEARALFYR
QYELLEYITR RGLPTTIKAG LKMLGQDVGA PRLPLQLLDA QGSAYLKGLL DALGEAD
//
