ID VIF_BIV29 Reviewed; 198 AA.
AC P19563; P19562; Q65591; Q65594;
DT 01-FEB-1991, integrated into UniProtKB/Swiss-Prot.
DT 01-FEB-1991, sequence version 1.
DT 08-NOV-2023, entry version 54.
DE RecName: Full=Virion infectivity factor;
DE AltName: Full=Q protein;
GN Name=vif;
OS Bovine immunodeficiency virus (strain R29) (BIV) (Bovine
OS immunodeficiency-like virus).
OC Viruses; Riboviria; Pararnavirae; Artverviricota; Revtraviricetes;
OC Ortervirales; Retroviridae; Orthoretrovirinae; Lentivirus;
OC Bovine immunodeficiency virus.
OX NCBI_TaxID=417296;
OH NCBI_TaxID=9913; Bos taurus (Bovine).
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC RNA].
RC STRAIN=Isolate R29-106, and Isolate R29-127;
RX PubMed=2183467; DOI=10.1016/0042-6822(90)90424-p;
RA Garvey K.J., Oberste M.S., Elser J.E., Braun M.J., Gonda M.A.;
RT "Nucleotide sequence and genome organization of biologically active
RT proviruses of the bovine immunodeficiency-like virus.";
RL Virology 175:391-409(1990).
RN [2]
RP NUCLEOTIDE SEQUENCE [MRNA].
RC STRAIN=Isolate R29-Nadin;
RA Nadin-Davis S.A., Chang S.C., Roth J.A., Carpenter S.;
RT "Isolation and characterization of cDNAs encoding rev and tat of bovine
RT immunodeficiency-like virus.";
RL Submitted (OCT-1992) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Determines virus infectivity.
CC -!- SUBCELLULAR LOCATION: Host cytoplasm {ECO:0000250}. Virion
CC {ECO:0000250}.
CC -!- MISCELLANEOUS: The sequence shown is that of isolate R29-127.
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DR EMBL; M32690; AAA91272.1; -; Genomic_RNA.
DR EMBL; L04972; AAA42768.1; -; Genomic_DNA.
DR EMBL; L04974; AAA42764.1; -; Genomic_DNA.
DR PIR; C34742; ASLJBT.
DR RefSeq; NP_040564.1; NC_001413.1.
DR GeneID; 1724697; -.
DR KEGG; vg:1724697; -.
DR GO; GO:0030430; C:host cell cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0044423; C:virion component; IEA:UniProtKB-KW.
DR InterPro; IPR009979; Lenti_VIF_2.
DR Pfam; PF07401; Lenti_VIF_2; 1.
DR PIRSF; PIRSF003854; Lenti_VIF_2; 1.
PE 2: Evidence at transcript level;
KW Host cytoplasm; Virion.
FT CHAIN 1..198
FT /note="Virion infectivity factor"
FT /id="PRO_0000085498"
FT REGION 1..31
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..30
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT VARIANT 4
FT /note="T -> P (in strain: Isolate R29-Nadin)"
FT VARIANT 66
FT /note="T -> I (in strain: Isolate R29-Nadin)"
FT VARIANT 79
FT /note="E -> K (in strain: Isolate R29-Nadin)"
FT VARIANT 84
FT /note="D -> N (in strain: Isolate R29-106)"
FT VARIANT 127
FT /note="T -> A (in strain: Isolate R29-Nadin)"
SQ SEQUENCE 198 AA; 22828 MW; BB9F4E732D52E89F CRC64;
MERTLQSVVG RRRGSSNRGR GKNSLISTPS YALHPPPRFR YPRWEFVRQT EYSMTACVRK
GKLVLTYQYA IWKRVWTIET GFTDPSLFMT PAGTHTTEEI GHLDLFWLRY CSCPHEMPPW
LDFLRGTLNL RISCRRALQA SVLTSTPRHS LQRLAALQLC TNACLCWYPL GRINDTTPLW
LNFSSGKEPT IQQLSGHP
//
