ID   VSR_RDVA                Reviewed;         353 AA.
AC   Q85447;
DT   01-DEC-2000, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   27-MAR-2024, entry version 45.
DE   RecName: Full=Suppressor of RNA-mediated gene silencing;
DE   AltName: Full=Non-structural protein 10;
DE            Short=Pns10;
OS   Rice dwarf virus (isolate Akita) (RDV).
OC   Viruses; Riboviria; Orthornavirae; Duplornaviricota; Resentoviricetes;
OC   Reovirales; Sedoreoviridae; Phytoreovirus; Rice dwarf virus.
OX   NCBI_TaxID=142803;
OH   NCBI_TaxID=114194; Alopecurus aequalis.
OH   NCBI_TaxID=90397; Echinochloa crus-galli (Barnyard grass) (Panicum crus-galli).
OH   NCBI_TaxID=94400; Nephotettix cincticeps (Green rice leafhopper) (Selenocephalus cincticeps).
OH   NCBI_TaxID=4530; Oryza sativa (Rice).
OH   NCBI_TaxID=147271; Paspalum.
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RX   PubMed=8503785; DOI=10.1007/bf01319009;
RA   Suzuki N.;
RT   "In vitro translation of rice dwarf phytoreovirus genome segments S4 to
RT   S10.";
RL   Arch. Virol. 130:201-208(1993).
CC   -!- FUNCTION: Suppressor of RNA-mediated gene silencing, also known as
CC       post-transcriptional gene silencing (PTGS), a mechanism of plant viral
CC       defense that limits the accumulation of viral RNAs. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the phytoreovirus non-structural protein 10
CC       family. {ECO:0000305}.
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DR   EMBL; D10221; BAA01073.1; -; mRNA.
DR   InterPro; IPR008777; Phytoreo_Pns.
DR   Pfam; PF05451; Phytoreo_Pns; 1.
PE   2: Evidence at transcript level;
KW   Host-virus interaction; Inhibition of host innate immune response by virus;
KW   Suppressor of RNA silencing; Viral immunoevasion.
FT   CHAIN           1..353
FT                   /note="Suppressor of RNA-mediated gene silencing"
FT                   /id="PRO_0000222797"
SQ   SEQUENCE   353 AA;  39196 MW;  AF6C2AE868186881 CRC64;
     MEVDTATFVR LHHELLCAHE GPSIISKFDA IKKVKLGTLA NQSGGVNNIT EAFLAKLRNF
     ERKSEAYLAS DLAERELTRD THKAIVFVTK SVLLGGKSLK DLLPYGVIVC AFIFIPETAS
     VLDNVPVMIG NQKRPLTVAL IKYIAKSLNC DLVGDSYDTF YYCNSSAYGK NLISVSDNDF
     SNPQRALLSV GDLCYQAARS LHVAAANYIR IFDRMPPGFQ PSKHLFRIIG VLDMETLKTM
     VTSNIAREPG MFCHDNVKDV LHRIGVYSPN HHFSAVILWK GWASTYAYMF NQEQLNMLSG
     TSGLAGDFGK YKLTYGSTFD EGVIHVQYQF VTPEVVRKRN IYPDLSALKG GGS
//