ID W0J1G3_9BACT Unreviewed; 342 AA.
AC W0J1G3;
DT 19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT 19-MAR-2014, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE SubName: Full=2-hydroxyacid dehydrogenase {ECO:0000313|EMBL:AHF90828.1};
GN ORFNames=OPIT5_12040 {ECO:0000313|EMBL:AHF90828.1};
OS Opitutaceae bacterium TAV5.
OC Bacteria; Verrucomicrobiota; Opitutae; Opitutales; Opitutaceae.
OX NCBI_TaxID=794903 {ECO:0000313|EMBL:AHF90828.1, ECO:0000313|Proteomes:UP000003813};
RN [1] {ECO:0000313|EMBL:AHF90828.1, ECO:0000313|Proteomes:UP000003813}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=TAV5 {ECO:0000313|EMBL:AHF90828.1};
RX PubMed=25744998;
RA Kotak M., Isanapong J., Goodwin L., Bruce D., Chen A., Han C.S.,
RA Huntemann M., Ivanova N., Land M.L., Nolan M., Pati A., Woyke T.,
RA Rodrigues J.L.;
RT "Complete Genome Sequence of the Opitutaceae Bacterium Strain TAV5, a
RT Potential Facultative Methylotroph of the Wood-Feeding Termite
RT Reticulitermes flavipes.";
RL Genome Announc. 3:0-0(2015).
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DR EMBL; CP007053; AHF90828.1; -; Genomic_DNA.
DR AlphaFoldDB; W0J1G3; -.
DR STRING; 794903.OPIT5_12040; -.
DR KEGG; obt:OPIT5_12040; -.
DR eggNOG; COG0111; Bacteria.
DR HOGENOM; CLU_019796_1_3_0; -.
DR Proteomes; UP000003813; Chromosome.
DR GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR GO; GO:0016614; F:oxidoreductase activity, acting on CH-OH group of donors; IEA:UniProt.
DR CDD; cd12167; 2-Hacid_dh_8; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 2.
DR InterPro; IPR029753; D-isomer_DH_CS.
DR InterPro; IPR006140; D-isomer_DH_NAD-bd.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR PANTHER; PTHR10996:SF178; 2-HYDROXYACID DEHYDROGENASE YGL185C-RELATED; 1.
DR PANTHER; PTHR10996; 2-HYDROXYACID DEHYDROGENASE-RELATED; 1.
DR Pfam; PF02826; 2-Hacid_dh_C; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR PROSITE; PS00671; D_2_HYDROXYACID_DH_3; 1.
PE 4: Predicted;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000003813}.
FT DOMAIN 154..302
FT /note="D-isomer specific 2-hydroxyacid dehydrogenase NAD-
FT binding"
FT /evidence="ECO:0000259|Pfam:PF02826"
SQ SEQUENCE 342 AA; 36625 MW; C274891CA1C66F61 CRC64;
MPRVLFALSG YDRNMFLPHL AYAIETLNEA ECVVPDTLPA KSEPGLWRAL LEETRPDVIV
SAWATPPVPA DWIAADSPAP CPLRYLCHLG GSVRQKVPRL FLERGGLVTN WGGQAAAQVA
EHALLLALAT LRRAPAWLGG ENGPPVRMIR IGDLDTRTLF GRRIGVHGCG SVARKLAALL
RPFECDVACF SAGVPDDVVH ASGMRPAGSL AELFGGKEIL FECEALTPAS ELCVDAAMLA
RLPDGALFVN VARGRLLDET ALLREVRSGR LQAALDVLTV EPVPADSPWR VQPGAIYSPH
IAGPTGDMMP RIGAAALENL INYLAGRPLG NLVSLDLYDR AT
//
