ID W0MX91_PSESX Unreviewed; 1129 AA.
AC W0MX91;
DT 19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT 19-MAR-2014, sequence version 1.
DT 24-JAN-2024, entry version 36.
DE SubName: Full=Potassium transporter KefA {ECO:0000313|EMBL:AHG43047.1};
GN ORFNames=N018_23585 {ECO:0000313|EMBL:AHG43047.1};
OS Pseudomonas syringae CC1557.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Pseudomonadales;
OC Pseudomonadaceae; Pseudomonas; Pseudomonas syringae.
OX NCBI_TaxID=1357279 {ECO:0000313|EMBL:AHG43047.1, ECO:0000313|Proteomes:UP000019089};
RN [1] {ECO:0000313|EMBL:AHG43047.1, ECO:0000313|Proteomes:UP000019089}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CC1557 {ECO:0000313|EMBL:AHG43047.1,
RC ECO:0000313|Proteomes:UP000019089};
RA Baltrus D., Hockett K., Karlsrud E., Dougherty K., Nishimura M.;
RT "Interactions Between Genome Architecture and Virulence Genes in
RT Pseudomonas syringae, strain CC1557 as a model.";
RL Submitted (DEC-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the MscS (TC 1.A.23) family.
CC {ECO:0000256|ARBA:ARBA00008017}.
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DR EMBL; CP007014; AHG43047.1; -; Genomic_DNA.
DR RefSeq; WP_025390846.1; NZ_CP007014.1.
DR AlphaFoldDB; W0MX91; -.
DR STRING; 1357279.N018_23585; -.
DR KEGG; psyr:N018_23585; -.
DR eggNOG; COG3264; Bacteria.
DR HOGENOM; CLU_007829_3_0_6; -.
DR Proteomes; UP000019089; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
DR Gene3D; 1.10.287.1260; -; 1.
DR Gene3D; 2.30.30.60; -; 1.
DR Gene3D; 3.30.70.100; -; 1.
DR InterPro; IPR010920; LSM_dom_sf.
DR InterPro; IPR049142; MS_channel_1st.
DR InterPro; IPR049278; MS_channel_C.
DR InterPro; IPR023408; MscS_beta-dom_sf.
DR InterPro; IPR006685; MscS_channel_2nd.
DR InterPro; IPR011066; MscS_channel_C_sf.
DR InterPro; IPR006686; MscS_channel_CS.
DR InterPro; IPR011014; MscS_channel_TM-2.
DR InterPro; IPR025692; MscS_IM_dom1.
DR InterPro; IPR024393; MscS_porin.
DR PANTHER; PTHR30347:SF8; MECHANOSENSITIVE CHANNEL MSCK; 1.
DR PANTHER; PTHR30347; POTASSIUM CHANNEL RELATED; 1.
DR Pfam; PF21088; MS_channel_1st; 1.
DR Pfam; PF00924; MS_channel_2nd; 1.
DR Pfam; PF21082; MS_channel_3rd; 1.
DR Pfam; PF12795; MscS_porin; 1.
DR Pfam; PF12794; MscS_TM; 1.
DR SUPFAM; SSF82689; Mechanosensitive channel protein MscS (YggB), C-terminal domain; 1.
DR SUPFAM; SSF82861; Mechanosensitive channel protein MscS (YggB), transmembrane region; 1.
DR SUPFAM; SSF50182; Sm-like ribonucleoproteins; 1.
DR PROSITE; PS01246; UPF0003; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..24
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 25..1129
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5004792987"
FT TRANSMEM 491..507
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 535..560
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 572..591
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 612..631
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 643..666
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 678..700
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 712..731
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 779..803
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 829..850
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 871..892
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 898..925
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 37..270
FT /note="Mechanosensitive ion channel MscS porin"
FT /evidence="ECO:0000259|Pfam:PF12795"
FT DOMAIN 491..809
FT /note="Mechanosensitive ion channel inner membrane"
FT /evidence="ECO:0000259|Pfam:PF12794"
FT DOMAIN 870..911
FT /note="Mechanosensitive ion channel transmembrane helices
FT 2/3"
FT /evidence="ECO:0000259|Pfam:PF21088"
FT DOMAIN 913..978
FT /note="Mechanosensitive ion channel MscS"
FT /evidence="ECO:0000259|Pfam:PF00924"
FT DOMAIN 986..1069
FT /note="Mechanosensitive ion channel MscS C-terminal"
FT /evidence="ECO:0000259|Pfam:PF21082"
FT REGION 1091..1129
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 221..248
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 1129 AA; 125822 MW; F1375155B304CC24 CRC64;
MFSLRSICAA ALFALCLSTF PALAADPPTA QAVQQSLDKI ADRKLSDADQ KALQQVLEQT
LGFLASKEDS EQKLKALKQQ LNEAPKQTTD NQRELARLKE SKIVPVTQRY GGLDVPQLEQ
LLSQRSTQQS DLQKELNDAN SLTITAQTRP ERAQAEISAN QTRIQQINNI LKNGKDNGKT
LTADQRNLLN AELASINALN LLRRQELAGN SQLQDLGGSQ HDLLTEKVAR QEQEIQDLQT
LINDKRRAQS QKTVAELSLE AQKSGGSSLL ATESAENLKL SDYLLRGTDR LNELTQQNLK
TKQQLDNLTQ TDQALSEQIN VLSGSLLLSK ILYKQKQSLP HLELDKGLAD EIANIRLYQF
DINQKREQMS TPNAYVDRLL ATQPPENVTP QLRRTLLDLA ITRSDLLERL NRELSALLNE
SITLQLNQKQ LTSTALSLRS TLDEQMFWIP SNKPLDLEWF QNIWPRLEKQ IATLPWTSSL
SELSDGLTQR PLLFLPLLLL IGVLTWRRKA LYQKLNRLHA DIGHFKRDSQ WKTPLALLIN
VLLAMPVALG LALCGYALQI DARGQNANLG EALLQIALAW LVFYTAYRVL APQGVAQLHF
RWETAQVEFL RGWIRRLGLV VLALVAVVAV AEHQPAALAD DVLGIGVVLT CYALMTWLLG
RLLISSPTHH NASLFRKAIG VAFTALPVAL FLAVCFGYYY TALKLSDRLI DTLYLMMIWL
MVEATFVRGL GVAARRLAYQ RALAKRQAAR ESGDSDIPVE EPKLDIEQVN QQSLRLIRLA
LLAGFVGALY LVWAELITVF AYLDNIILYE YTSGTGANMS MVPISLSDFL GAGVIIVTTF
VLAGNLPGLL EVLVLSRMNL AQGSAYATTT LLSYTIAGIG FVTTLSTLGV SWDKLQWLVA
ALSVGLGFGM QEIFANFISG IMILFERPVR IGDTITIGAL SGTVSKIRIR ATTITDFDRK
DIIVPNKTFI TGQLINWSLT DTITRVTLKL GVDYGSDLDL VRSLLLQAAR ENPRVLKDPE
PIVYFLNFGE STLDHELRMH VRDLGDRNPV LDEINRFINR EFKKQHINIS FRQMEIYLKN
TQGLEYKLVP AEPAEKGDAQ TGKTTLQPVD TKVAPATKDA PEPPELRLD
//
