ID W0YJD4_TOBAC Unreviewed; 348 AA.
AC W0YJD4;
DT 19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT 19-MAR-2014, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE RecName: Full=Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha {ECO:0000256|ARBA:ARBA00040965};
DE EC=2.5.1.58 {ECO:0000256|ARBA:ARBA00012702};
DE EC=2.5.1.59 {ECO:0000256|ARBA:ARBA00012700};
DE AltName: Full=CAAX farnesyltransferase subunit alpha {ECO:0000256|ARBA:ARBA00043086};
DE AltName: Full=FTase-alpha {ECO:0000256|ARBA:ARBA00042436};
DE AltName: Full=Ras proteins prenyltransferase subunit alpha {ECO:0000256|ARBA:ARBA00041392};
DE AltName: Full=Type I protein geranyl-geranyltransferase subunit alpha {ECO:0000256|ARBA:ARBA00043219};
GN Name=Ntalpha {ECO:0000313|EMBL:CDI30233.1};
GN Synonyms=LOC107814428 {ECO:0000313|RefSeq:XP_016495328.1};
OS Nicotiana tabacum (Common tobacco).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae;
OC Nicotiana.
OX NCBI_TaxID=4097 {ECO:0000313|EMBL:CDI30233.1};
RN [1] {ECO:0000313|Proteomes:UP000084051}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. TN90 {ECO:0000313|Proteomes:UP000084051};
RX PubMed=24807620; DOI=10.1038/ncomms4833;
RA Sierro N., Battey J.N., Ouadi S., Bakaher N., Bovet L., Willig A.,
RA Goepfert S., Peitsch M.C., Ivanov N.V.;
RT "The tobacco genome sequence and its comparison with those of tomato and
RT potato.";
RL Nat. Commun. 5:3833-3833(2014).
RN [2] {ECO:0000313|EMBL:CDI30233.1}
RP NUCLEOTIDE SEQUENCE.
RX DOI=10.1104/pp.113.232546;
RA Huchelmann A., Gastaldo C., Veinante M., Zeng Y., Heintz D., Tritsch D.,
RA Schaller H., Rohmer M., Bach T.J., Hemmerlin A.;
RT "S-Carvone suppresses cellulase-induced capsidiol production in Nicotiana
RT tabacum by interfering with protein isoprenylation.";
RL Plant Physiol. 0:0-0(2014).
RN [3] {ECO:0000313|RefSeq:XP_016495328.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- COFACTOR:
CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC Evidence={ECO:0000256|ARBA:ARBA00001946};
CC -!- SIMILARITY: Belongs to the protein prenyltransferase subunit alpha
CC family. {ECO:0000256|ARBA:ARBA00006734}.
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DR EMBL; HG518669; CDI30233.1; -; Genomic_DNA.
DR RefSeq; XP_016495328.1; XM_016639842.1.
DR STRING; 4097.W0YJD4; -.
DR PaxDb; 4097-W0YJD4; -.
DR GeneID; 107814428; -.
DR KEGG; nta:107814428; -.
DR OMA; HRHTIID; -.
DR OrthoDB; 20949at2759; -.
DR Proteomes; UP000084051; Unplaced.
DR GO; GO:0005953; C:CAAX-protein geranylgeranyltransferase complex; IBA:GO_Central.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0005965; C:protein farnesyltransferase complex; IBA:GO_Central.
DR GO; GO:0008318; F:protein prenyltransferase activity; IEA:InterPro.
DR Gene3D; 1.25.40.120; Protein prenylyltransferase; 1.
DR InterPro; IPR002088; Prenyl_trans_a.
DR PANTHER; PTHR11129; PROTEIN FARNESYLTRANSFERASE ALPHA SUBUNIT/RAB GERANYLGERANYL TRANSFERASE ALPHA SUBUNIT; 1.
DR PANTHER; PTHR11129:SF1; PROTEIN FARNESYLTRANSFERASE_GERANYLGERANYLTRANSFERASE TYPE-1 SUBUNIT ALPHA; 1.
DR Pfam; PF01239; PPTA; 4.
DR SUPFAM; SSF48439; Protein prenylyltransferase; 1.
DR PROSITE; PS51147; PFTA; 5.
PE 3: Inferred from homology;
KW Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW Prenyltransferase {ECO:0000256|ARBA:ARBA00022602};
KW Reference proteome {ECO:0000313|Proteomes:UP000084051};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transferase {ECO:0000313|EMBL:CDI30233.1}.
SQ SEQUENCE 348 AA; 40315 MW; 2C3A653AFBAA35AD CRC64;
MDTGEDKRTR IPFKERPEWA DVKPVPQDDG PCPVVPIAYT EDFSETMDYF RAIYLDDERS
PRALQLTAEA IPLNPGNYTV WQFRRVVLEA LGVDLHEELK FVDRIAGENT KNYQIWHHRR
WLAEKLRTDA VTNELEFTKK IFSQDAKNYH AWSHRQWVLQ ALGGWENELA YCQQLLEDDI
YNNSAWNQRY FVVTRSPLLG GLAAMRELEV NYTVQALRAS PENESPWRYL RGLYKNDTQS
LVEDSQVASV LLDVLTSKNN HVHALSLLLD LLSHGFEPRE ELKSAVDVLT PQSCSPDLPL
AKRICSILEH ADPMRINYWN WRKSTIPVQS AKCQNTDRLA DLSMQDNL
//
