ID   W0Z4R0_9MICO            Unreviewed;       469 AA.
AC   W0Z4R0;
DT   19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT   19-MAR-2014, sequence version 1.
DT   24-JAN-2024, entry version 35.
DE   SubName: Full=Aminomethyltransferase {ECO:0000313|EMBL:CDJ98985.1};
DE            EC=2.1.2.10 {ECO:0000313|EMBL:CDJ98985.1};
GN   Name=gcvT {ECO:0000313|EMBL:CDJ98985.1};
GN   ORFNames=MIC448_1100042 {ECO:0000313|EMBL:CDJ98985.1};
OS   Microbacterium sp. C448.
OC   Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Microbacteriaceae;
OC   Microbacterium.
OX   NCBI_TaxID=1177594 {ECO:0000313|EMBL:CDJ98985.1, ECO:0000313|Proteomes:UP000028883};
RN   [1] {ECO:0000313|EMBL:CDJ98985.1, ECO:0000313|Proteomes:UP000028883}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=C448 {ECO:0000313|EMBL:CDJ98985.1,
RC   ECO:0000313|Proteomes:UP000028883};
RX   PubMed=24526651; DOI=10.1128/genomeA.01113-13;
RA   Martin-Laurent F., Marti R., Waglechner N., Wright G.D., Topp E.;
RT   "Draft Genome Sequence of the Sulfonamide Antibiotic-Degrading
RT   Microbacterium sp. Strain C448.";
RL   Genome Announc. Announc.2:e01113-e01113(2014).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:CDJ98985.1}.
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DR   EMBL; CBVQ010000014; CDJ98985.1; -; Genomic_DNA.
DR   RefSeq; WP_036298653.1; NZ_HG779690.1.
DR   AlphaFoldDB; W0Z4R0; -.
DR   STRING; 1177594.MIC448_1100042; -.
DR   eggNOG; COG0404; Bacteria.
DR   HOGENOM; CLU_046852_1_0_11; -.
DR   OrthoDB; 2055370at2; -.
DR   Proteomes; UP000028883; Unassembled WGS sequence.
DR   GO; GO:0004047; F:aminomethyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR   InterPro; IPR028896; GCST/YgfZ/DmdA.
DR   InterPro; IPR006222; GCV_T_N.
DR   InterPro; IPR027266; TrmE/GcvT_dom1.
DR   PANTHER; PTHR43757; AMINOMETHYLTRANSFERASE; 1.
DR   PANTHER; PTHR43757:SF2; AMINOMETHYLTRANSFERASE, MITOCHONDRIAL; 1.
DR   Pfam; PF01571; GCV_T; 1.
DR   SUPFAM; SSF103025; Folate-binding domain; 1.
PE   4: Predicted;
KW   Methyltransferase {ECO:0000313|EMBL:CDJ98985.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000028883};
KW   Transferase {ECO:0000313|EMBL:CDJ98985.1}.
FT   DOMAIN          33..257
FT                   /note="Aminomethyltransferase folate-binding"
FT                   /evidence="ECO:0000259|Pfam:PF01571"
SQ   SEQUENCE   469 AA;  51858 MW;  B4A93EE0086F23B1 CRC64;
     MAPKNLQEVI DAAGSPVELL RNSQIGSYIY PVVPADFQNW IKEQKAWRDT AVLYDQSHHM
     DNVFLKGSDA IKLISDTAIN SVANFAVNKA KQYVPTTASG HVIGDGILFR EAEDEYVYVG
     RAPASNWLMF HGETGGYQNL EVVVDRRSPS RPYGDAVARK YYRFQIQGPN AWAVIEKLNG
     GPLEKLGFFN MSEMKIGNMN VRTLRHGMAG APGLEIWGPY AEHHQIRDLI VEAGQEFGLL
     PVGSRAYPSN TLESGWIPSP LPAIYTGAEE QAYREWLPAD SYEATGTLAG SFVSDNIEDY
     YLTPWELGYG SFVKFDHDFI GRDALEKMDQ AGQRKKVTLA WDAEDLGKVW TSLLNVDGPN
     YKFFDLPLAN YGSANYDSVV DADGTVVGYS MFTGYSSNER RGLSLATIDP SVPEGTELKV
     VWGEPNGGTK KASVEPHEQT EVRAVVSPIP YSTVARATYQ GGWRTGYSD
//