ID   W1DIR8_KLEPN            Unreviewed;       301 AA.
AC   W1DIR8;
DT   19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT   19-MAR-2014, sequence version 1.
DT   27-MAR-2024, entry version 46.
DE   SubName: Full=Phosphogluconate repressor HexR, RpiR family {ECO:0000313|EMBL:CDL08540.1};
OS   Klebsiella pneumoniae IS43.
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Klebsiella/Raoultella group; Klebsiella.
OX   NCBI_TaxID=1432552 {ECO:0000313|EMBL:CDL08540.1, ECO:0000313|Proteomes:UP000019183};
RN   [1] {ECO:0000313|EMBL:CDL08540.1, ECO:0000313|Proteomes:UP000019183}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=IS43 {ECO:0000313|EMBL:CDL08540.1,
RC   ECO:0000313|Proteomes:UP000019183};
RA   Barisic I., Mitteregger D., Hirschl A.M., Noehammer C., Wiesinger-Mayr H.;
RT   "Antibiotic resistance diversity of beta-lactamase producers in the General
RT   Hospital Vienna.";
RL   Submitted (OCT-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:CDL08540.1}.
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DR   EMBL; CBWK010000211; CDL08540.1; -; Genomic_DNA.
DR   AlphaFoldDB; W1DIR8; -.
DR   eggNOG; COG1737; Bacteria.
DR   Proteomes; UP000019183; Unassembled WGS sequence.
DR   GO; GO:0097367; F:carbohydrate derivative binding; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   GO; GO:1901135; P:carbohydrate derivative metabolic process; IEA:InterPro.
DR   CDD; cd05013; SIS_RpiR; 1.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR009057; Homeobox-like_sf.
DR   InterPro; IPR000281; HTH_RpiR.
DR   InterPro; IPR047640; RpiR-like.
DR   InterPro; IPR035472; RpiR-like_SIS.
DR   InterPro; IPR001347; SIS_dom.
DR   InterPro; IPR046348; SIS_dom_sf.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   PANTHER; PTHR30514; GLUCOKINASE; 1.
DR   PANTHER; PTHR30514:SF1; HTH-TYPE TRANSCRIPTIONAL REGULATOR HEXR-RELATED; 1.
DR   Pfam; PF01418; HTH_6; 1.
DR   Pfam; PF01380; SIS; 1.
DR   SUPFAM; SSF46689; Homeodomain-like; 1.
DR   SUPFAM; SSF53697; SIS domain; 1.
DR   PROSITE; PS51071; HTH_RPIR; 1.
DR   PROSITE; PS51464; SIS; 1.
PE   4: Predicted;
FT   DOMAIN          13..89
FT                   /note="HTH rpiR-type"
FT                   /evidence="ECO:0000259|PROSITE:PS51071"
FT   DOMAIN          133..272
FT                   /note="SIS"
FT                   /evidence="ECO:0000259|PROSITE:PS51464"
SQ   SEQUENCE   301 AA;  33318 MW;  60669ABAC96432F3 CRC64;
     MKSFPLMSAL LLMNMLEKIQ SRLEHLSKSE RKVAEVILAT PEQAIHSSIA ALALEAGVSE
     PTVNRFCRSL ETRGFPDFKL HLAQSLAHGT LYVNRNVDED DSVESYTGKI FESAMASLDQ
     VHHSLDMSAV NRAVDLLTQA KKIAFFGLGS SAAVAHDAMN KFFRFNVPVI YSDDIVLQRM
     SCMNCDDDDV VVIISHTGRT KSLVELAQLA RENDAMVIAL TSAGTPLARE ATLAITLDVP
     EDTDIYMPMV SRLAQLTVID VLATGFTLRR GAKFRDNLKR VKEALKESRF DKEPFVPSDN
     Q
//