ID W1J6D4_9GAMM Unreviewed; 541 AA.
AC W1J6D4;
DT 19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT 19-MAR-2014, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE SubName: Full=Putative 3-hydroxybutyryl-CoA dehydrogenase {ECO:0000313|EMBL:CDL85030.1};
DE EC=1.1.1.157 {ECO:0000313|EMBL:CDL85030.1};
GN Name=paaH {ECO:0000313|EMBL:CDL85030.1};
GN ORFNames=XSR1_60076 {ECO:0000313|EMBL:CDL85030.1};
OS Xenorhabdus szentirmaii DSM 16338.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Morganellaceae; Xenorhabdus.
OX NCBI_TaxID=1427518 {ECO:0000313|EMBL:CDL85030.1, ECO:0000313|Proteomes:UP000019202};
RN [1] {ECO:0000313|EMBL:CDL85030.1, ECO:0000313|Proteomes:UP000019202}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 16338 {ECO:0000313|EMBL:CDL85030.1,
RC ECO:0000313|Proteomes:UP000019202};
RA Gualtieri M., Ogier J.C., Pages S., Givaudan A., Gaudriault S.;
RT "Draft genome sequence and annotation of the entomopathogenic bacteria,
RT Xenorhabdus cabanillasi strain JM26 and Xenorhabdus szentirmai strain DSM
RT 16338.";
RL Submitted (NOV-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- PATHWAY: Lipid metabolism; butanoate metabolism.
CC {ECO:0000256|ARBA:ARBA00005086}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CDL85030.1}.
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DR EMBL; CBXF010000121; CDL85030.1; -; Genomic_DNA.
DR RefSeq; WP_038240981.1; NZ_NIBV01000001.1.
DR AlphaFoldDB; W1J6D4; -.
DR STRING; 1427518.XSR1_60076; -.
DR OrthoDB; 5389341at2; -.
DR Proteomes; UP000019202; Unassembled WGS sequence.
DR GO; GO:0008691; F:3-hydroxybutyryl-CoA dehydrogenase activity; IEA:UniProtKB-EC.
DR GO; GO:0070403; F:NAD+ binding; IEA:InterPro.
DR GO; GO:0044248; P:cellular catabolic process; IEA:UniProt.
DR GO; GO:0006631; P:fatty acid metabolic process; IEA:InterPro.
DR GO; GO:1901575; P:organic substance catabolic process; IEA:UniProt.
DR Gene3D; 3.30.750.190; -; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR006176; 3-OHacyl-CoA_DH_NAD-bd.
DR InterPro; IPR006108; 3HC_DH_C.
DR InterPro; IPR041040; 3HCDH_RFF.
DR InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR InterPro; IPR013328; 6PGD_dom2.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR PANTHER; PTHR48075; 3-HYDROXYACYL-COA DEHYDROGENASE FAMILY PROTEIN; 1.
DR PANTHER; PTHR48075:SF5; 3-HYDROXYACYL-COA DEHYDROGENASE FAMILY PROTEIN; 1.
DR Pfam; PF00725; 3HCDH; 2.
DR Pfam; PF02737; 3HCDH_N; 1.
DR Pfam; PF18321; 3HCDH_RFF; 1.
DR SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 2.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 4: Predicted;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000313|EMBL:CDL85030.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000019202}.
FT DOMAIN 10..186
FT /note="3-hydroxyacyl-CoA dehydrogenase NAD binding"
FT /evidence="ECO:0000259|Pfam:PF02737"
FT DOMAIN 190..287
FT /note="3-hydroxyacyl-CoA dehydrogenase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF00725"
FT DOMAIN 369..437
FT /note="3-hydroxybutyryl-CoA dehydrogenase reduced Rossmann-
FT fold"
FT /evidence="ECO:0000259|Pfam:PF18321"
FT DOMAIN 440..519
FT /note="3-hydroxyacyl-CoA dehydrogenase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF00725"
FT REGION 296..317
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 541 AA; 59631 MW; 900A4416308492BE CRC64;
MTTPLLHGPI AVIGAGTMGI GIAQVAAQAG HSVLLFDVDH AATHHALDNL RIRLSQRVEA
GKAEADAIQA LLQRINPVDS LQSLAPCALV IEAIVEQLEA KQHLFHQLES ICSANTLFVS
NTSSLSITAI ARVLSSPQRM AGLHFFNPAP LMKLVEIVQG LETSAQTVAT LSSLITHWKK
QPVTCRSTPG FIVNRIARPF YAESLRALEE HIATPATLDA VMKESGGFMM GPMQLMDLIG
HDINYTVTES LFHAFYGDSR FQPSLHQKEL VDAGHLGRKR GRGFYFYKGP YKENQVNKES
WPQPNIEPRQ PNKEKKQSVR IKATGNWHAL PHFATLLKQS KLPHCSIAFE ESKNDRLHSP
SLQIDDVILT LAKGRTCAQI ADEIRAPVMQ FDLSANYQSA SMMTLSRAGR NAPGQTAKVI
SFLQSLGKQV ILLPDYPGLL TMRTVAMLCN EALDAVNKGI ASADDIDLAM RYGVNYPIGP
LAWGEQLGWK HILSTLENLQ KFYGETRYRP APLLRSLAAG HEKLPFSRQH SHQDKESFHA
G
//
