ID W1QAF0_OGAPD Unreviewed; 802 AA.
AC W1QAF0;
DT 19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT 19-MAR-2014, sequence version 1.
DT 27-MAR-2024, entry version 43.
DE SubName: Full=Molecular chaperone of the endoplasmic reticulum lumen {ECO:0000313|EMBL:ESW97374.1};
DE EC=3.6.1.3 {ECO:0000313|EMBL:ESW97374.1};
GN ORFNames=HPODL_01473 {ECO:0000313|EMBL:ESW97374.1};
OS Ogataea parapolymorpha (strain ATCC 26012 / BCRC 20466 / JCM 22074 / NRRL
OS Y-7560 / DL-1) (Yeast) (Hansenula polymorpha).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Pichiaceae; Ogataea.
OX NCBI_TaxID=871575 {ECO:0000313|EMBL:ESW97374.1, ECO:0000313|Proteomes:UP000008673};
RN [1] {ECO:0000313|EMBL:ESW97374.1, ECO:0000313|Proteomes:UP000008673}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 26012 / BCRC 20466 / JCM 22074 / NRRL Y-7560 / DL-1
RC {ECO:0000313|Proteomes:UP000008673};
RX PubMed=24279325; DOI=10.1186/1471-2164-14-837;
RA Ravin N.V., Eldarov M.A., Kadnikov V.V., Beletsky A.V., Schneider J.,
RA Mardanova E.S., Smekalova E.M., Zvereva M.I., Dontsova O.A., Mardanov A.V.,
RA Skryabin K.G.;
RT "Genome sequence and analysis of methylotrophic yeast Hansenula polymorpha
RT DL1.";
RL BMC Genomics 14:837-837(2013).
RN [2] {ECO:0000313|Proteomes:UP000008673}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 26012 / BCRC 20466 / JCM 22074 / NRRL Y-7560 / DL-1
RC {ECO:0000313|Proteomes:UP000008673};
RA Ravin N.V., Mardanov A.V., Eldarov M.A., Kadnikov V.V., Beletsky A.V.,
RA Zvereva M.I., Smekalova E.M., Dontsova O.A., Skryabin K.G.;
RT "Genome sequence of the methylotrophic yeast Hansenula polymorpha DL1.";
RL Submitted (OCT-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ESW97374.1}.
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DR EMBL; AEOI02000009; ESW97374.1; -; Genomic_DNA.
DR RefSeq; XP_013933459.1; XM_014077984.1.
DR AlphaFoldDB; W1QAF0; -.
DR STRING; 871575.W1QAF0; -.
DR GeneID; 25770934; -.
DR KEGG; opa:HPODL_01473; -.
DR eggNOG; KOG0104; Eukaryota.
DR HOGENOM; CLU_005965_5_0_1; -.
DR OMA; DYGQQNI; -.
DR OrthoDB; 5491443at2759; -.
DR Proteomes; UP000008673; Chromosome VI.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0140662; F:ATP-dependent protein folding chaperone; IEA:InterPro.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR CDD; cd10230; HYOU1-like_NBD; 1.
DR Gene3D; 1.20.1270.10; -; 1.
DR Gene3D; 3.30.30.30; -; 1.
DR Gene3D; 3.30.420.40; -; 2.
DR InterPro; IPR043129; ATPase_NBD.
DR InterPro; IPR018181; Heat_shock_70_CS.
DR InterPro; IPR029048; HSP70_C_sf.
DR InterPro; IPR013126; Hsp_70_fam.
DR PANTHER; PTHR45639; HSC70CB, ISOFORM G-RELATED; 1.
DR PANTHER; PTHR45639:SF3; HYPOXIA UP-REGULATED PROTEIN 1; 1.
DR Pfam; PF00012; HSP70; 1.
DR PRINTS; PR00301; HEATSHOCK70.
DR SUPFAM; SSF53067; Actin-like ATPase domain; 2.
DR PROSITE; PS01036; HSP70_3; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Hydrolase {ECO:0000313|EMBL:ESW97374.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000008673};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..18
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 19..802
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5004808166"
FT REGION 773..802
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 802 AA; 89432 MW; 530CBBCA3C7B6D11 CRC64;
MKVLGLVALI FVIVQGWASL LAIDFGQDYS KAALVAPGVA FDLILTDEAK RKHQSGVAIS
AKDGEIERKF NSHALSACTR SPQSCFFELK SLIGRQIDEP QVTRFEKKYR GVKIVPASSQ
RRTVAFDVDG QVYLLEEVLG MVLEEIKKRA ELHWDQTLGG GSSNTISDVV LSVPGFLDQA
QRTALVDAAE IAGLNVVALI DDGLAVALNY ASTRDFEQKQ YHVIYDVGAG STKATLVSFS
KENETLRVEN EGYGYDETFG GNLFTESLQA IIEDKFLAQN KIKPETLWSD ARAMNRLWQS
AEKAKLVLSA NSETKVSVES LINDIDLKVV VSRDEFEEYM TEHMDRIVAP LAAAVGDRKV
ESVILAGGST RVPFVQKHLV KYLGSDELLS KNVNADEAAV FGTLLGGISV SGKFRTRPIE
LVQHATRNFE LAAGGQMTVV FNETTASREA SVALPGVKDT FGDVQVDFFE AGQLFAQYKF
KNELNSTVCP NGVEYFANCT LDPRKLFVLR SLEAVCVGDE AVRSSLTAKP SHPGYKPLGS
LAKYQSASRL RSLTNQDKQR QQRDALINSL EASLYDLRGY TEDENVVANG PPSMVRAARK
MVSELLEWLE DVPAKATVKD IQEKYDDVRV MRIKLETLVN HGDRLLSLEE FTRLKEKALE
TMYKLQDFMV VMSQDALSLR ANFTELGLDF EEANRRVKVK VPEVDEQELE QRMKRISDFV
GVVDHFETHK DEIDTKDKET LFDLRETVLE ELKEVQSTYR ALKQAHEKRI RGLKEQLKKA
DKKPEGAGDK TQETEPSGHD EL
//
