ID W1QCD9_OGAPD Unreviewed; 554 AA.
AC W1QCD9;
DT 19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT 19-MAR-2014, sequence version 1.
DT 27-MAR-2024, entry version 39.
DE SubName: Full=Sorting nexin-41 {ECO:0000313|EMBL:ESW98716.1};
GN ORFNames=HPODL_04328 {ECO:0000313|EMBL:ESW98716.1};
OS Ogataea parapolymorpha (strain ATCC 26012 / BCRC 20466 / JCM 22074 / NRRL
OS Y-7560 / DL-1) (Yeast) (Hansenula polymorpha).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Pichiaceae; Ogataea.
OX NCBI_TaxID=871575 {ECO:0000313|EMBL:ESW98716.1, ECO:0000313|Proteomes:UP000008673};
RN [1] {ECO:0000313|EMBL:ESW98716.1, ECO:0000313|Proteomes:UP000008673}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 26012 / BCRC 20466 / JCM 22074 / NRRL Y-7560 / DL-1
RC {ECO:0000313|Proteomes:UP000008673};
RX PubMed=24279325; DOI=10.1186/1471-2164-14-837;
RA Ravin N.V., Eldarov M.A., Kadnikov V.V., Beletsky A.V., Schneider J.,
RA Mardanova E.S., Smekalova E.M., Zvereva M.I., Dontsova O.A., Mardanov A.V.,
RA Skryabin K.G.;
RT "Genome sequence and analysis of methylotrophic yeast Hansenula polymorpha
RT DL1.";
RL BMC Genomics 14:837-837(2013).
RN [2] {ECO:0000313|Proteomes:UP000008673}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 26012 / BCRC 20466 / JCM 22074 / NRRL Y-7560 / DL-1
RC {ECO:0000313|Proteomes:UP000008673};
RA Ravin N.V., Mardanov A.V., Eldarov M.A., Kadnikov V.V., Beletsky A.V.,
RA Zvereva M.I., Smekalova E.M., Dontsova O.A., Skryabin K.G.;
RT "Genome sequence of the methylotrophic yeast Hansenula polymorpha DL1.";
RL Submitted (OCT-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the sorting nexin family.
CC {ECO:0000256|ARBA:ARBA00010883}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ESW98716.1}.
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DR EMBL; AEOI02000008; ESW98716.1; -; Genomic_DNA.
DR RefSeq; XP_013934599.1; XM_014079124.1.
DR AlphaFoldDB; W1QCD9; -.
DR STRING; 871575.W1QCD9; -.
DR GeneID; 25773756; -.
DR KEGG; opa:HPODL_04328; -.
DR eggNOG; KOG2273; Eukaryota.
DR HOGENOM; CLU_035999_0_0_1; -.
DR OMA; DFKDPWG; -.
DR OrthoDB; 5475877at2759; -.
DR Proteomes; UP000008673; Chromosome V.
DR GO; GO:0005829; C:cytosol; IEA:GOC.
DR GO; GO:0005768; C:endosome; IEA:UniProtKB-KW.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
DR GO; GO:0042147; P:retrograde transport, endosome to Golgi; IEA:InterPro.
DR CDD; cd06867; PX_SNX41_42; 1.
DR Gene3D; 3.30.1520.10; Phox-like domain; 1.
DR InterPro; IPR001683; PX_dom.
DR InterPro; IPR036871; PX_dom_sf.
DR InterPro; IPR044106; PX_Snx41/Atg20.
DR PANTHER; PTHR46979; SORTING NEXIN-41; 1.
DR PANTHER; PTHR46979:SF2; SORTING NEXIN-41; 1.
DR Pfam; PF00787; PX; 1.
DR SMART; SM00312; PX; 1.
DR SUPFAM; SSF64268; PX domain; 1.
DR PROSITE; PS50195; PX; 1.
PE 3: Inferred from homology;
KW Endosome {ECO:0000256|ARBA:ARBA00022753};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Reference proteome {ECO:0000313|Proteomes:UP000008673}.
FT DOMAIN 50..181
FT /note="PX"
FT /evidence="ECO:0000259|PROSITE:PS50195"
FT REGION 24..43
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 420..440
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 452..471
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 554 AA; 63528 MW; 24BE39A9D9295B46 CRC64;
MDYDEFSNDN NPFAGSNHFY SNGISTTIET GEPQDSDTSG ASLGVQSLDS QPLVSHMPAQ
SSDSANVLIT NYEVLRDFKN ITTVFYKIEY MSNSVLRRYT DFVFLRSYLT KLFQTKVIPP
IPEKHSLGRL IKNPFTYKSD TKIIYRRIRL LQYFLTELIS DPEIKQAEVF VKFLDSSQRN
WLQMVKSGHV ASLSSKSVLL TSPRNPTIPN PYLVYLPVPP LGLAKKYDSS LNSRIFVPLE
KKAKLLLQRV QGLEQTSKKL IKDFEKNRLA MVELGGFFNI FSILEDQQKH IEEFGNRIDL
TFLNIEILTK SITVKIYEPL IILRLTLVAI LHLLHYRKLK ELQLSYLQEI IVKKQIRLRS
LMERVTSEFK LNQVLHNNSV DSPSLNRAIN ELKIKKQKRK QLDESSLIII NEQLHKDDDD
ESFIRDHDNN STLSKGNQGN WKTAIAGTSS SASSNKIHTR ATSSHKSVSK LTPDELGSEM
CTARLELSEK LTPCFTNLML DVKYISLEVE KNVNHQLAKV IQRLHDIMSD WQTVVFSEFA
HSCRKIWSND TCLS
//
