ID W2D3H1_9PSED Unreviewed; 349 AA.
AC W2D3H1;
DT 19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT 19-MAR-2014, sequence version 1.
DT 27-MAR-2024, entry version 43.
DE SubName: Full=Putative LacI family regulatory protein {ECO:0000313|EMBL:ETK13954.1};
GN ORFNames=H096_32066 {ECO:0000313|EMBL:ETK13954.1};
OS Pseudomonas sp. FH1.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Pseudomonadales;
OC Pseudomonadaceae; Pseudomonas.
OX NCBI_TaxID=1284392 {ECO:0000313|EMBL:ETK13954.1, ECO:0000313|Proteomes:UP000018863};
RN [1] {ECO:0000313|EMBL:ETK13954.1, ECO:0000313|Proteomes:UP000018863}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=FH1 {ECO:0000313|EMBL:ETK13954.1,
RC ECO:0000313|Proteomes:UP000018863};
RX PubMed=24286439; DOI=10.1111/1462-2920.12345;
RA Rhodes G., Bosma H., Studholme D., Arnold D.L., Jackson R.W., Pickup R.W.;
RT "The rulB gene of plasmid pWW0 is a hotspot for the site-specific insertion
RT of integron-like elements found in the chromosomes of environmental
RT Pseudomonas fluorescens group bacteria.";
RL Environ. Microbiol. 16:2374-2388(2014).
CC -!- SUBCELLULAR LOCATION: Periplasm {ECO:0000256|ARBA:ARBA00004418}.
CC -!- SIMILARITY: Belongs to the bacterial solute-binding protein 2 family.
CC {ECO:0000256|ARBA:ARBA00007639}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ETK13954.1}.
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DR EMBL; AOHM01000142; ETK13954.1; -; Genomic_DNA.
DR RefSeq; WP_033903171.1; NZ_AOHM01000142.1.
DR AlphaFoldDB; W2D3H1; -.
DR PATRIC; fig|1284392.3.peg.6244; -.
DR Proteomes; UP000018863; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0030288; C:outer membrane-bounded periplasmic space; IEA:UniProt.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd01392; HTH_LacI; 1.
DR CDD; cd06307; PBP1_sugar_binding; 1.
DR Gene3D; 3.40.50.2300; -; 2.
DR Gene3D; 1.10.260.40; lambda repressor-like DNA-binding domains; 1.
DR InterPro; IPR000843; HTH_LacI.
DR InterPro; IPR010982; Lambda_DNA-bd_dom_sf.
DR InterPro; IPR028082; Peripla_BP_I.
DR InterPro; IPR025997; SBP_2_dom.
DR PANTHER; PTHR30146; LACI-RELATED TRANSCRIPTIONAL REPRESSOR; 1.
DR PANTHER; PTHR30146:SF149; TRANSCRIPTIONAL REGULATORY PROTEIN; 1.
DR Pfam; PF00356; LacI; 1.
DR Pfam; PF13407; Peripla_BP_4; 1.
DR SMART; SM00354; HTH_LACI; 1.
DR SUPFAM; SSF47413; lambda repressor-like DNA-binding domains; 1.
DR SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
DR PROSITE; PS50932; HTH_LACI_2; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 69..92
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 7..62
FT /note="HTH lacI-type"
FT /evidence="ECO:0000259|PROSITE:PS50932"
SQ SEQUENCE 349 AA; 37370 MW; 4222EAE19933C53A CRC64;
MNNNKRPTIA TVAAQAGLSV ATVDRVLNAR APVNPETAEQ VFQAAEAVGY FAARLIGQRI
RERRPTYRFG ILLLATAQAF YASLAQAISA AAEQHAGANL TCQFEYIVDR TPAAIVAQIE
QLAVQCDGLA VVSFAHPLIN ACLKQIREAG VPVVALLSDI HEQAEEPYVG QDNHVVGRTM
GWLLARTCGA RKGSVGILLG GHRFLGHQAR VEGLHSYLAE HAPGLKPLEP LINLDNCDIT
EEATLDLISR HSDLRGLCVV GGGGDGIISA LAQLPKRPAL CCILQESTEL SRQALGQGLI
DVVMDSQPGQ TATALVRLMV ELQSAEGFDP VRQRVYVPPQ IVTSENRGN
//
