ID W2F181_9ACTN Unreviewed; 334 AA.
AC W2F181;
DT 19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT 19-MAR-2014, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE SubName: Full=NADPH:quinone reductase {ECO:0000313|EMBL:ETK36986.1};
GN ORFNames=MPTA5024_06090 {ECO:0000313|EMBL:ETK36986.1};
OS Microbispora sp. ATCC PTA-5024.
OC Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
OC Streptosporangiaceae; Microbispora.
OX NCBI_TaxID=316330 {ECO:0000313|EMBL:ETK36986.1, ECO:0000313|Proteomes:UP000018869};
RN [1] {ECO:0000313|EMBL:ETK36986.1, ECO:0000313|Proteomes:UP000018869}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC PTA-5024 {ECO:0000313|EMBL:ETK36986.1,
RC ECO:0000313|Proteomes:UP000018869};
RX PubMed=24459268;
RA Sosio M., Gallo G., Pozzi R., Serina S., Monciardini P., Bera A.,
RA Stegmann E., Weber T.;
RT "Draft Genome Sequence of the Microbispora sp. Strain ATCC-PTA-5024,
RT Producing the Lantibiotic NAI-107.";
RL Genome Announc. 2:e01198-13(2014).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ETK36986.1}.
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DR EMBL; AWEV01000060; ETK36986.1; -; Genomic_DNA.
DR RefSeq; WP_036320562.1; NZ_KI866522.1.
DR AlphaFoldDB; W2F181; -.
DR STRING; 316330.MPTA5024_06090; -.
DR PATRIC; fig|316330.3.peg.1179; -.
DR HOGENOM; CLU_026673_3_3_11; -.
DR OrthoDB; 3727682at2; -.
DR Proteomes; UP000018869; Unassembled WGS sequence.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR CDD; cd08267; MDR1; 1.
DR Gene3D; 3.90.180.10; Medium-chain alcohol dehydrogenases, catalytic domain; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR013154; ADH-like_N.
DR InterPro; IPR011032; GroES-like_sf.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR020843; PKS_ER.
DR InterPro; IPR002364; Quin_OxRdtase/zeta-crystal_CS.
DR PANTHER; PTHR11695; ALCOHOL DEHYDROGENASE RELATED; 1.
DR PANTHER; PTHR11695:SF294; RETICULON-4-INTERACTING PROTEIN 1, MITOCHONDRIAL; 1.
DR Pfam; PF08240; ADH_N; 1.
DR Pfam; PF13602; ADH_zinc_N_2; 1.
DR SMART; SM00829; PKS_ER; 1.
DR SUPFAM; SSF50129; GroES-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR PROSITE; PS01162; QOR_ZETA_CRYSTAL; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000018869}.
FT DOMAIN 10..326
FT /note="Enoyl reductase (ER)"
FT /evidence="ECO:0000259|SMART:SM00829"
SQ SEQUENCE 334 AA; 36048 MW; 178C01FCB848F1BE CRC64;
MKAFVLRSYG SPEVLELREV PMPVPRRDEV LVRVRATSVQ PYDWHLMRGQ PYVARLMGDP
AGVRAPRRRV LGADVAGQVE EVGTDVTRYR PGDEVYAMPK QGGFGEYVCV PESELARKPR
NLSFEEAAAV PLAANTALLA LRDRGRIEAG QSVLVDGASG GVGTFAVQLA KAFGAKVTGV
CSGRNADLVR SIGADEVVDY TREDVTASGR RHDLLIDIWG GRSLRTCRRA LVRGGTHVLV
GGPGGRWLQP VGRIAAALAT APFASCRTVT ANVVGCAENG RNLATLTGLI EDGLVRPIVD
RCHRFEEIPE AVRYQEEGRS RGKVVVTVWD GTLP
//
