ID W2GY39_PHYPR Unreviewed; 868 AA.
AC W2GY39;
DT 19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT 19-MAR-2014, sequence version 1.
DT 27-MAR-2024, entry version 39.
DE RecName: Full=Transferrin receptor-like dimerisation domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=L915_07754 {ECO:0000313|EMBL:ETK87887.1}, L916_07683
GN {ECO:0000313|EMBL:ETL41306.1};
OS Phytophthora parasitica (Potato buckeye rot agent).
OC Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC Phytophthora.
OX NCBI_TaxID=4792 {ECO:0000313|EMBL:ETK87887.1};
RN [1] {ECO:0000313|EMBL:ETK87887.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CJ02B3 {ECO:0000313|EMBL:ETK87887.1};
RG The Broad Institute Genomics Platform;
RA Russ C., Tyler B., Panabieres F., Shan W., Tripathy S., Grunwald N.,
RA Machado M., Johnson C.S., Arredondo F., Hong C., Coffey M., Young S.K.,
RA Zeng Q., Gargeya S., Fitzgerald M., Abouelleil A., Alvarado L.,
RA Chapman S.B., Gainer-Dewar J., Goldberg J., Griggs A., Gujja S., Hansen M.,
RA Howarth C., Imamovic A., Ireland A., Larimer J., McCowan C., Murphy C.,
RA Pearson M., Poon T.W., Priest M., Roberts A., Saif S., Shea T., Sykes S.,
RA Wortman J., Nusbaum C., Birren B.;
RT "The Genome Sequence of Phytophthora parasitica CJ02B3.";
RL Submitted (NOV-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ETL41306.1, ECO:0000313|Proteomes:UP000053864}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CJ05E6 {ECO:0000313|EMBL:ETL41306.1,
RC ECO:0000313|Proteomes:UP000053864};
RG The Broad Institute Genomics Platform;
RA Russ C., Tyler B., Panabieres F., Shan W., Tripathy S., Grunwald N.,
RA Machado M., Johnson C.S., Arredondo F., Hong C., Coffey M., Young S.K.,
RA Zeng Q., Gargeya S., Fitzgerald M., Abouelleil A., Alvarado L.,
RA Chapman S.B., Gainer-Dewar J., Goldberg J., Griggs A., Gujja S., Hansen M.,
RA Howarth C., Imamovic A., Ireland A., Larimer J., McCowan C., Murphy C.,
RA Pearson M., Poon T.W., Priest M., Roberts A., Saif S., Shea T., Sykes S.,
RA Wortman J., Nusbaum C., Birren B.;
RT "The Genome Sequence of Phytophthora parasitica CJ05E6.";
RL Submitted (NOV-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the peptidase M28 family. M28B subfamily.
CC {ECO:0000256|ARBA:ARBA00005634}.
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DR EMBL; KI686056; ETK87887.1; -; Genomic_DNA.
DR EMBL; KI672677; ETL41306.1; -; Genomic_DNA.
DR EnsemblProtists; ETK87887; ETK87887; L915_07754.
DR EnsemblProtists; ETL41306; ETL41306; L916_07683.
DR VEuPathDB; FungiDB:PPTG_10900; -.
DR Proteomes; UP000053236; Unassembled WGS sequence.
DR Proteomes; UP000053864; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR Gene3D; 3.50.30.30; -; 1.
DR Gene3D; 1.20.930.40; Transferrin receptor-like, dimerisation domain; 1.
DR Gene3D; 3.40.630.10; Zn peptidases; 2.
DR InterPro; IPR046450; PA_dom_sf.
DR InterPro; IPR003137; PA_domain.
DR InterPro; IPR007484; Peptidase_M28.
DR InterPro; IPR039373; Peptidase_M28B.
DR InterPro; IPR007365; TFR-like_dimer_dom.
DR InterPro; IPR036757; TFR-like_dimer_dom_sf.
DR PANTHER; PTHR10404:SF46; GLUTAMATE CARBOXYPEPTIDASE 2 HOMOLOG; 1.
DR PANTHER; PTHR10404; N-ACETYLATED-ALPHA-LINKED ACIDIC DIPEPTIDASE; 1.
DR Pfam; PF02225; PA; 1.
DR Pfam; PF04389; Peptidase_M28; 1.
DR Pfam; PF04253; TFR_dimer; 1.
DR SUPFAM; SSF52025; PA domain; 1.
DR SUPFAM; SSF47672; Transferrin receptor-like dimerisation domain; 1.
DR SUPFAM; SSF53187; Zn-dependent exopeptidases; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 68..90
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 223..301
FT /note="PA"
FT /evidence="ECO:0000259|Pfam:PF02225"
FT DOMAIN 436..570
FT /note="Peptidase M28"
FT /evidence="ECO:0000259|Pfam:PF04389"
FT DOMAIN 750..861
FT /note="Transferrin receptor-like dimerisation"
FT /evidence="ECO:0000259|Pfam:PF04253"
FT REGION 283..302
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 868 AA; 94006 MW; F57CE512F6E306CD CRC64;
MGVSDDRASI IKGDALKVLP ELDLDEDDSN VDESKVPLTR SNVYADSPRE VHLSEGITEA
EIILRQRVGI AFVLGLIVAS AICVMLLGLL GHEENYGSTP AIQHHFIAAT SADGFKKNLE
FYTDVIRHTG STGDYEMAQF IRSSAINFGF EESSIKIDEF EMLVNAPETL TLDILDLSKN
ESLASYDFVA EHAARQAKRQ AKGKNLTKPY AAFHLYSKNG TASGPIVYAH FGSSEDYQAL
AQNNINVAGK IVLVRMGGDV SLPAKVVIAS KFGAVGVLTY TDPADDGSAR GPTAPDGPWR
PSSTSTFGNV YMGDGDPTMP EGFSATRPMG TTADRLSIED IYSVNNTFNI LPPIVSMAIS
AAVAQDLLTQ IETASKKIAT LKQINAADVF GARWEGGALG VKYMLPVDDD TSKSEEVGII
VKMTNSNVYT LTTTWNVVIT VYGSREPDRH VLVGAPRDSL NAGAVSPGSG NAVFLEVLRA
LGTLVANGWT PYRTLVLASF GGEQFGSVGS SHWIDRYPSF GSGNAGRGVV YLHLDDVVRG
AGALRCKASA TIRKNIYLMS AAVAQPKKQD YPDVDSFFFS NASGASAVAA GSSSKDEDDL
DMLPVNATFS SNELPGSGNS VFAYWLEDAN KKNPSGVELE LPPMERNLGA RISPFLGRLG
IPSLELGFDG GYFGVGNTGA DIPAWISHFA DPQFAFHRAA AELYGSILLS FTDAQFLQYD
FTELSRELRR GEAFLEDALA REGLIEVVPL GRLHNATTAF ETAAISVNHE MNVISDQEHD
FSRIRLFNNR LLRAQRAFLL PSGLTYMPWI KNVLYGISEW DDYRVSLFPG VTHELKRGNA
MTVRRELVRL CITIEAATDI LMNAPDEE
//
