ID   W2IPM8_PHYPR            Unreviewed;       505 AA.
AC   W2IPM8;
DT   19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT   19-MAR-2014, sequence version 1.
DT   27-MAR-2024, entry version 37.
DE   RecName: Full=XPG-I domain-containing protein {ECO:0000259|SMART:SM00484};
GN   ORFNames=L916_11822 {ECO:0000313|EMBL:ETL36174.1};
OS   Phytophthora parasitica (Potato buckeye rot agent).
OC   Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC   Phytophthora.
OX   NCBI_TaxID=4792 {ECO:0000313|EMBL:ETL36174.1};
RN   [1] {ECO:0000313|EMBL:ETL36174.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CJ05E6 {ECO:0000313|EMBL:ETL36174.1};
RG   The Broad Institute Genomics Platform;
RA   Russ C., Tyler B., Panabieres F., Shan W., Tripathy S., Grunwald N.,
RA   Machado M., Johnson C.S., Arredondo F., Hong C., Coffey M., Young S.K.,
RA   Zeng Q., Gargeya S., Fitzgerald M., Abouelleil A., Alvarado L.,
RA   Chapman S.B., Gainer-Dewar J., Goldberg J., Griggs A., Gujja S., Hansen M.,
RA   Howarth C., Imamovic A., Ireland A., Larimer J., McCowan C., Murphy C.,
RA   Pearson M., Poon T.W., Priest M., Roberts A., Saif S., Shea T., Sykes S.,
RA   Wortman J., Nusbaum C., Birren B.;
RT   "The Genome Sequence of Phytophthora parasitica CJ05E6.";
RL   Submitted (NOV-2013) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; KI673854; ETL36174.1; -; Genomic_DNA.
DR   AlphaFoldDB; W2IPM8; -.
DR   EnsemblProtists; ETL36174; ETL36174; L916_11822.
DR   VEuPathDB; FungiDB:PPTG_13796; -.
DR   Proteomes; UP000053864; Unassembled WGS sequence.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0035312; F:5'-3' DNA exonuclease activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006281; P:DNA repair; IEA:UniProtKB-UniRule.
DR   CDD; cd09901; H3TH_FEN1-like; 1.
DR   Gene3D; 1.10.150.20; 5' to 3' exonuclease, C-terminal subdomain; 1.
DR   Gene3D; 3.40.50.1010; 5'-nuclease; 1.
DR   InterPro; IPR036279; 5-3_exonuclease_C_sf.
DR   InterPro; IPR008918; HhH2.
DR   InterPro; IPR029060; PIN-like_dom_sf.
DR   InterPro; IPR006086; XPG-I_dom.
DR   InterPro; IPR006084; XPG/Rad2.
DR   PANTHER; PTHR11081:SF72; 5'-3' EXONUCLEASE FAMILY PROTEIN; 1.
DR   PANTHER; PTHR11081; FLAP ENDONUCLEASE FAMILY MEMBER; 1.
DR   Pfam; PF00867; XPG_I; 1.
DR   PRINTS; PR00853; XPGRADSUPER.
DR   SMART; SM00279; HhH2; 1.
DR   SMART; SM00484; XPGI; 1.
DR   SUPFAM; SSF47807; 5' to 3' exonuclease, C-terminal subdomain; 1.
DR   SUPFAM; SSF88723; PIN domain-like; 1.
PE   4: Predicted;
KW   Mitochondrion {ECO:0000256|ARBA:ARBA00023128};
KW   Phosphoprotein {ECO:0000256|ARBA:ARBA00022553}.
FT   DOMAIN          10..80
FT                   /note="XPG-I"
FT                   /evidence="ECO:0000259|SMART:SM00484"
FT   REGION          225..293
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          343..457
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          477..505
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        225..270
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        271..287
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        403..429
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        436..457
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   505 AA;  56069 MW;  9840CD1D87A9560F CRC64;
     MAMKLIAVLR RMNITFYVAP YEADAQLAFL SKQRIVDVVI SQDSDCVPYG VKTVLFKLSP
     DGWGSELKRR SLGANEELSF VGWTEEMFIQ LCVLAGCDYC PSVSGVGIIT AYKLVSTYKT
     PTEVLKALQQ QKGSSVPQDY PEQFYSAILT YRHQLVFDPR DAKLKMLSPL DISKDILPLV
     DKGLHFLGNV ELRDDVVASI AAGEIHPITH ESYVWKDTAA AMLLDEQTTS KPNTSRTRSS
     TSSESSGMIL PHRRDDQSTN NSSQEDPVNT RAEISRLRYE KPRPSSRSSW THLDSVLGSS
     DHIVNFRSPK VSENFKPLAA LHDLPSSSIN AQDLKEFERR PVRDHVKRVR NPANRRRDGK
     GSGFEGEVLC KVDQGRTSSL GLTTDDRLTD EENAPPQAKR PKLSGCPSSS SSLSSRVSDA
     GSQSQLVRPT PFGCGRPSSP TASSHLNWKL PPRHSQRTIQ QNAFAMSAEE KWDRILGDEL
     DTDSQVSDQG RPPLAPINEV RRDVS
//