ID W2KME0_PHYPR Unreviewed; 5308 AA.
AC W2KME0;
DT 19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT 19-MAR-2014, sequence version 1.
DT 27-MAR-2024, entry version 48.
DE RecName: Full=Calmodulin {ECO:0008006|Google:ProtNLM};
GN ORFNames=L917_14972 {ECO:0000313|EMBL:ETL85510.1};
OS Phytophthora parasitica (Potato buckeye rot agent).
OC Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC Phytophthora.
OX NCBI_TaxID=4792 {ECO:0000313|EMBL:ETL85510.1};
RN [1] {ECO:0000313|EMBL:ETL85510.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CHvinca01 {ECO:0000313|EMBL:ETL85510.1};
RG The Broad Institute Genomics Platform;
RA Russ C., Tyler B., Panabieres F., Shan W., Tripathy S., Grunwald N.,
RA Machado M., Johnson C.S., Arredondo F., Hong C., Coffey M., Young S.K.,
RA Zeng Q., Gargeya S., Fitzgerald M., Abouelleil A., Alvarado L.,
RA Chapman S.B., Gainer-Dewar J., Goldberg J., Griggs A., Gujja S., Hansen M.,
RA Howarth C., Imamovic A., Ireland A., Larimer J., McCowan C., Murphy C.,
RA Pearson M., Poon T.W., Priest M., Roberts A., Saif S., Shea T., Sykes S.,
RA Wortman J., Nusbaum C., Birren B.;
RT "The Genome Sequence of Phytophthora parasitica CHvinca01.";
RL Submitted (NOV-2013) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; KI681596; ETL85510.1; -; Genomic_DNA.
DR EnsemblProtists; ETL85510; ETL85510; L917_14972.
DR VEuPathDB; FungiDB:PPTG_04733; -.
DR Proteomes; UP000054423; Unassembled WGS sequence.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd00030; C2; 3.
DR CDD; cd04508; Tudor_SF; 1.
DR Gene3D; 2.60.40.150; C2 domain; 4.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR000008; C2_dom.
DR InterPro; IPR035892; C2_domain_sf.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR001849; PH_domain.
DR PANTHER; PTHR45911; C2 DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR45911:SF10; DYSFERLIN-RELATED; 1.
DR Pfam; PF00168; C2; 5.
DR Pfam; PF00169; PH; 1.
DR SMART; SM00239; C2; 6.
DR SMART; SM00233; PH; 2.
DR SUPFAM; SSF49562; C2 domain (Calcium/lipid-binding domain, CaLB); 4.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR PROSITE; PS50004; C2; 4.
DR PROSITE; PS50003; PH_DOMAIN; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils}.
FT DOMAIN 5..105
FT /note="PH"
FT /evidence="ECO:0000259|PROSITE:PS50003"
FT DOMAIN 124..257
FT /note="C2"
FT /evidence="ECO:0000259|PROSITE:PS50004"
FT DOMAIN 300..431
FT /note="C2"
FT /evidence="ECO:0000259|PROSITE:PS50004"
FT DOMAIN 638..768
FT /note="C2"
FT /evidence="ECO:0000259|PROSITE:PS50004"
FT DOMAIN 2276..2412
FT /note="C2"
FT /evidence="ECO:0000259|PROSITE:PS50004"
FT REGION 107..139
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 924..959
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1823..1844
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2257..2290
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 4348..4405
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 4997..5024
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 113..139
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1828..1844
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2270..2288
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 4363..4405
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 5308 AA; 599419 MW; 0AD2AA7878C58F67 CRC64;
MSDQRCIKEG WLQKRSRPGK LVGNWRRRYF RLTSTELAYY KSPQDVAPRR RYELTLDSSV
LRTNDQGYSN CIAFQAAPGQ PSFYMLADNE DEKEEWTTAI YNAYRRTPDV AQQPPAPEIP
KATPESTPPQ PPPPPAPPSR ILLKLVVEEA RKLKAADMNG KSDPYCIVKL IGKDGKTIEV
EEKRTDVISA TLEPVWKASF EIGRVVDLNS VKAVRFDLMD HDTLQRHDSL GTVEVPFSRF
RMSSASTVQS EPIDEWFRVN PPKKTGLSSS FREKEHVVKD WGELHVKMSI TGPNLVDFFH
NSELEFVPTS PVATATKEHT DNRLEVTVLA ARNLISVDAN DSSDPYCELT LLDDNGRPIS
SEYATTATMH RTRNPTWANE HHVFGLICPI ETAASLKVRV VDYDKTNRND PLGFVIIHLE
QLSAHKWTEW HALQPEEGMS NRANLGEIQL KIWLIGERRG EHARRLKIDK ELHLKAHSQS
VEQLEYENAQ IEMYDAACKL DGARIPCAVT DYQAHDPRFY GINGCIHYLN SQIPRAHQEK
TSTDESFQAR TGLEGQALLE VTVIQASDLK QNQKAGDKPS TATPYAVIEL DPSVCVEECK
RTSAPLSPKK SKRVAAGEAR NTMFSKRAQG EVSMHRTKLA KNEMRSESPL EINPDILVLK
VEIRTGHALS PADMNGYSDP YCTLSLTDRT TGKAIEAEKK RTAVMSKTLN PVWTNEIFVF
GNNVPLLDAK SLLVHVKDHN NIGRSTPLGR VEIPLSDLCR ESVDSTSISS TEVVKRYELK
PEPWMKKSAK ELGELCIKTE FVGNTTALAE LVQRMSSAPI ENSSSSSEAK IQSEASIDTN
MSMLDLDESE FEDEKTEILQ LGAPIKTSTS KILGTNSTAT WDKEKFSLSL SYPGLFSDAK
YPNMDTQLLQ LRVHEARNLL ISAAAGDRSN TGPSATERDA VEGPTNSKAQ NPTQRQRNAT
NVYFTVVPVR RDGTLEDAER IQSLTVYNAR DPSWPVQEFV FGKVKDIANV SYLSLHMYER
DVESDQESVL SNLLTDKEKK LDVCLKRFQL HKLSSSGEVE DDDFELLQFG QRVLAFRGGE
DGGRFYPACI QRYIPFPDDE YEVRFDDEIN TIDELRNLIS LDVKGVVQAE RSDGRLDVAV
DNESTNSVKR SSRYVVKPSQ LVPVNSLTGS VERLMARRLD VVKEENERWA RMQHMVSGIV
VDVLSASDLV VPVIKDGKLQ KMKHLDKNDN LECRVTLLGK PRQKEPNLCY FNDRGELFTS
ETMSQSTWKW EKDKQLEATI GAQNETNDNE SGASEKDNSV LLFQNQPLVI GRVEKISPTD
AKETKVEYRY QPVDPNEAKV GCQILEQTSS ILIQVNAQVK VENQDETGSK KNLKKEIHVK
ESRLLNVTLG YAKIDLAMLR SKQQTLRLQI VPLKSANVPY FKSVGSLFVR ISTSSDDCKM
KTVRALVKAE DPEHPRLFEL SSWYEKQLQL EAVSSSLFTR GVTWIERRQL LRTSLSPTEN
AQIDALHTVL VIVMKRIVNI LREIQQFEAF EALCVDEMRM SRLVHTVNAD PGSEYLGRTM
DKLPHEVRKE IVVGLENELL DLAGVSGPRI YPAVDTSREE WMRLRTERQK LLQEYGNFFM
RDQTSALVVS VPKSFTGEGI IAWFRRRPSV LWDDKWEVYC NDAAIISSCK LGWRSQSLEY
DPDALQAPTD DVHVLQWMSA LCAAGYVENV TPGIGFGKRR VLLECRDDYF YRLREVDMWM
ENLSRESSLF PLDLVQEIDC YQEKSLEQNN AGTENEQTQT TTKETRSYAK KLTEYCDGFL
GMHTMLSSVL FAVKDLKNAL MPPVVEKPSD NTGNTEKGSV ASAEEQGTVQ VVESILWDWK
YCLFMPSRKH VYIYENETST APVAFIDMAS AVCKVAYNFS NDVKGGWMDI VNPTVYVRKP
NSREFESVTP EILNKMTKPR ANGDKVIEVK TSSTQKWIQA LARSGVCVDM RPGQEVLMKR
LNPIILQQKC NKHATEFDPN DLEGSFQRLL NRLFGHDKGL TYQDHETERR ELRAQVRSEL
KKAGNEGDTV MAYYGKGKNR RSKPMNSGNF KNDSLYPGRI LRIRTPFTDE KYPFKTTYDM
TDTNEVPTEL AKLLAKYKVV DKTSWLSLPK SQRDMFLLYV VEYSHANERI VEEGLMREHI
RTNEGDLDPQ KVSDKCADLN ILFKATDLEN CVSRMVKHRY RHKSLGVLKI HTKMISPHRT
IDAWYPLAPA SDMLQRTNLG QVRVELKLVQ KREVTRSAKL PPIPENVRTD ELTPQDQGKS
TVSQATDSKG RLPFAVGREP SFVKVSILEG RSLPVADMFT SDSFVEIILL DENSKERDTS
LKTDIKMKTL NPKWENQEFL LGKTEKTKLS DKKGILLRVM DYDAASANDP LGCVTIEFQR
REGYIRGLVL KQADAYGNAD TRDLKLEDHS RVEVEAMLLP ISGKPKPKKT PAPDGVLGKL
RFVVEIIRND SSVNVIEKRI EKRLEATTSY SAEIAIKKAI KNTGAQEDWS KYSCYFQPRG
EAGARVKCDS ASEDLGFGNS YKLSDLLSST ASLSSSGKAT QASSSIYAGA FKILGRTYDL
SKVDYFDVRL ASESTGKTFE GQLGKSDQTT KDLEGKHKFS LKTPNQCASF RDETVVLTER
DSKETLTLTF DLNLIGILRA DRVRRLLADT FRLVGLAFDS RTFNHTGGRY NLEQLHKDVE
MFLWENSQAN LIPGRNVAEE LLTQLRIMSQ ASKLHWKATP QLLGYVFELV LLSGDNDRLS
YASAVALDAV LNRWSRVLVQ VTEAREYLTG NFHGKKTPRL IEALFTECEW TGFNVMTLSD
GDNGTTTNKQ RLSPFSIDDR VTVRLPFLKH AGVVVDTQLH EGRFVAARIV KECGAGLFNV
KICDVLGNEV TLGDAQERVG KLKEYDNAKH PEAPYLVEYL DGLEPRVEWR THRLMSEIVL
QVEGELLKSE LEPGDFVHIS EEHIVLSAEL TTGVSRVDDN TDTSSTIITG KTRPGKITNR
HGGARYDVVF TDGLVPVNAK VVNRSRLIPM CNETMYDGRI TSIYAPVAVL EGPPPPIKYT
VCLENGEVVH NFSGTQIRPR YGVFAADTAF LGAVFSSNLP TLDKNRHVPD STLNMAKSLE
KLWWGSDKIL KVYAMLPAAV KSIQVRNATT NKLLQTALLE RNENEPRFIG QYHGFVKGET
LDEKEAHQLE LVHNAVCKRR QHNGSLKMAP QFSKEKCFYL IVASPPLVQI RGQVRVCSSP
YSEALFKGLV MATLGSTPDL AVTVVQRLLR AECSKIPRAG SKECRVAIKC AKVEFAKNPT
RDVVLNLMHP SSKKAAIDAD LAGVSWLDAC IDIKFQLSVP YNDQGNISEA VATAYENAST
ISKRLQTFNT LAVEVNMLAP DTVDMEKLSW LLTTSDINLK SSMALSIDFS SQTGRSDLKP
EVSLEPLDDI RVSVRDSHDK THDLHFRIDD ILAEAAVRRN LTPFHKAIVV APPSENESMR
CRVRFLPTSS NKSNAGADVE NKRTGEVDVP TGSIRFDKLR VKVVEASNMK FKEKMGNEGL
QVEVMLVSSD FDKHMTVSSG KKTTTPFGLE VSSTGELLPD IYPKNSSFTL MYDTTQVVKQ
TSDASVKWRV KNGPPYVEFK YPVIDMDRVS EVRLVIRDKK TQAKMGIVTI PMGSISISRS
VEDIDKPKDE PIYSMQRDGA DGKRAVVGTL SLSVERIQKY SANDEVYAKH LEKPMDFWTI
CPKELLKLTL EQHESKLSRS FLAAGPPVSG EGKILLSTAI DMELQLQKIA KVQRIDAIAK
LQSSTSSRSV ALLSSSNEFQ NFENLKSRAM DTLQQTLQQT KSFMKDTAHE LGLGHYMTEH
RLPWSSDTQV DKHESQLRDD VVVVEANVAT CTNRVQLSVL KLHEVLTKHF IPKLDELYTL
DADDDRVDIT KGESLLSFFD TEVEELEPED EKVRLKLYQR LRLTKLIQVL DLIMKASVRV
KVMNEDRNNV DGYIGTACIP LMDLLDQQPH DDVYELLYLP TTNLRGSRIA VEARGANDRG
KLRLRLHLKI SESSFFEQAI EVYKVWKAKY IAQHEAARRR IHDAVVPAQR RRWTTVKGYL
DELTAQTSGK LHWERTPVLL SLVWDIFTIQ ESTSAQSKKK SDADEAEHSH SIAKMADNYR
GAVMKVHQRW VNLQPKLDEL LIIQATTQIH AHRTPDILED IEKEIEGLDV GLSTAWKQVK
QKWQTLLEAL EELVRMNEGK LNLARAPQLL STVEQRCSKG LNTRHSDAVS QIQSRWMAIT
QPNGPLSELR LMEKKGLHWR RTHELLLLLD EQCEGFADVD ARALNTVQTR WEQVQEWLHE
VVQMQLQHSI DSEHTPFILE KMQLWKPTRG KKQEENKLER SRSASGVAPS SPSAKDNTAS
RQPGLSRQYS VSSDGGFTSG SGIEDNGQLE GMAEWYAIEE AKYELERIPY HRITMDSDKK
NWLPFSRDGK DSRLLITQEE MFFTPANVRL ALEDRGVIPK TSTFDLTADS TSNASAKEDV
WVKPSLLDSK SGSQTVVLPK HVDEEIKRLE KVLESQRENS QQLTLPNPER VAELYQAMES
LGKTELLRNV SHAVSRNLEL AVQENYQLLL REMTSRQIST TEVENLVESL AITLRKETLV
AKGITVPDTV DPTTLRQLME EHEIREVALP QDTSSIQTLL DERGMDHKGE PVMLRGVRIG
TQSTQTGNTK AINTGLGIID TQVETLRRTL LFEALRKRNS LVRSFAGESH VLDEETERTE
ADMFAAAIEN AEVDVSGDYL TLVERFQRLL VHESYTKRLA EYAALDRCMR ALLGKSRDEV
VTKEEIAMEL HNVNKRVIGA NYRLPPEAFT REELFQAVAA GRIRTPSDEM LSHCPEGENS
SAMAHYAAIS YAANVFQEVT SFRSRVDVAK NRLQDTFPYD ECSSLDGVFL QKQRTRQTLS
QSIADWLLGF DASALSIKRK LSAAHRQRLE WASAAFTLRN RWLQRGLGWC DHEFEGVGVK
YLLDRLLLFE AANKMDMVKT EKLLREVRDK CSRLRDREQE AQTKLEERYQ ANLALLEKLV
THAERCMNNR KLHSEETPVL LHKLEQVCVV PKGLNDRHRE AYHTVATHWL PHQQHLAELV
KMHREGTFSI TRTPELLGKM QYHTEGKAGS EELSEDKVAA SAQRVAPELQ ATFVDRKLDE
VRLGQRKEPS SLHLNLNTEE NVDQSADDTE WKELSPSKRV VQPLSPHEKQ TSWKVVRNAV
AANAAFSAAS PSKTKPEKAK VEIAPKVAPP PSPRRRLSLS DELKELLRSP TQWFTGTGQQ
EEYIRAELYF PEQLVLDTAS DLLSDPTK
//
