ID W2LHI9_PHYPR Unreviewed; 707 AA.
AC W2LHI9;
DT 19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT 19-MAR-2014, sequence version 1.
DT 27-MAR-2024, entry version 39.
DE RecName: Full=PH domain-containing protein {ECO:0000259|PROSITE:PS50003};
GN ORFNames=L917_05741 {ECO:0000313|EMBL:ETL96871.1};
OS Phytophthora parasitica (Potato buckeye rot agent).
OC Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC Phytophthora.
OX NCBI_TaxID=4792 {ECO:0000313|EMBL:ETL96871.1};
RN [1] {ECO:0000313|EMBL:ETL96871.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CHvinca01 {ECO:0000313|EMBL:ETL96871.1};
RG The Broad Institute Genomics Platform;
RA Russ C., Tyler B., Panabieres F., Shan W., Tripathy S., Grunwald N.,
RA Machado M., Johnson C.S., Arredondo F., Hong C., Coffey M., Young S.K.,
RA Zeng Q., Gargeya S., Fitzgerald M., Abouelleil A., Alvarado L.,
RA Chapman S.B., Gainer-Dewar J., Goldberg J., Griggs A., Gujja S., Hansen M.,
RA Howarth C., Imamovic A., Ireland A., Larimer J., McCowan C., Murphy C.,
RA Pearson M., Poon T.W., Priest M., Roberts A., Saif S., Shea T., Sykes S.,
RA Wortman J., Nusbaum C., Birren B.;
RT "The Genome Sequence of Phytophthora parasitica CHvinca01.";
RL Submitted (NOV-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
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DR EMBL; KI678831; ETL96871.1; -; Genomic_DNA.
DR AlphaFoldDB; W2LHI9; -.
DR EnsemblProtists; ETL96871; ETL96871; L917_05741.
DR VEuPathDB; FungiDB:PPTG_02187; -.
DR Proteomes; UP000054423; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR CDD; cd00821; PH; 2.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 3.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR001849; PH_domain.
DR PANTHER; PTHR14336:SF8; DUAL ADAPTER FOR PHOSPHOTYROSINE AND 3-PHOSPHOTYROSINE AND 3-PHOSPHOINOSITIDE; 1.
DR PANTHER; PTHR14336; TANDEM PH DOMAIN CONTAINING PROTEIN; 1.
DR Pfam; PF00169; PH; 1.
DR SMART; SM00233; PH; 3.
DR SUPFAM; SSF50729; PH domain-like; 3.
DR PROSITE; PS50003; PH_DOMAIN; 2.
PE 4: Predicted;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490}.
FT DOMAIN 288..378
FT /note="PH"
FT /evidence="ECO:0000259|PROSITE:PS50003"
FT DOMAIN 509..599
FT /note="PH"
FT /evidence="ECO:0000259|PROSITE:PS50003"
FT REGION 168..203
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 233..279
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 249..274
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 707 AA; 79029 MW; DE82B9649793A65D CRC64;
MVTQRVAPIR PDDASAYHAG KTTLDAMLAR QDRSPHSVEQ AEALDDGYDD TAPLGLAVNT
RNYQALLDNL ARRRRTNSGA SVASGGVSPA YQRQTLAVCQ QQMDNQLESP TLAQTVTVDE
EEEDEEERDR TVVGLPVDTR NYEAIVSGSR PIHSDPGTFN LLNRRATVAT MPQMPQPVKD
SEEMRPDQNQ AGDTGEDDAV MGLPISTGNY VAYLAGQQGS GIQQAGHRNR GYSNLAQEKE
PRVSDPYLSS SRRGRSPPDS YTTAPSNNNQ DDPRPSCFDN RRASNAAYVP HSGWVFIQHG
AFKTWKRYYA VLSGTEFKYS KGVGQSPKGF GLLMSVRKLD SLRYGLFLEF GDGSTLQIRC
SNEKEFDQWL DAMEKVIERN QNLNSQSKTS YTLTASEQHE GYLFKQEKNK AWKRCFFVVR
IDGYIECRDH ERGTVDRKCS GYIKAVSFAD CHANGLAIQL STDVSMVCYA DSYDEQMLWY
GAISAAATAN GKTAQPKTSV KSCYVQTALS NHAGWLYKQA GLFKGWKRLY FTLHGVELAY
AKDTNSETVL SDKAHSVEEW EGHANGLLIR LISGRVWKVH AESYETAKRW RSVISSACRH
AETFNLKKYL NSRRRKKLRP VFGGWLTEVR KGSRLRRFYV MDGATLGVAN DVDNQLERLG
TVVDVGSTRD LECGIVFTLS NGTKLKVNCD SLADSRCWYE CLNFSLK
//
