ID   W2LSX0_PHYPR            Unreviewed;       682 AA.
AC   W2LSX0;
DT   19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT   19-MAR-2014, sequence version 1.
DT   27-MAR-2024, entry version 38.
DE   SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:ETL99774.1};
GN   ORFNames=L917_03419 {ECO:0000313|EMBL:ETL99774.1};
OS   Phytophthora parasitica (Potato buckeye rot agent).
OC   Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC   Phytophthora.
OX   NCBI_TaxID=4792 {ECO:0000313|EMBL:ETL99774.1};
RN   [1] {ECO:0000313|EMBL:ETL99774.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CHvinca01 {ECO:0000313|EMBL:ETL99774.1};
RG   The Broad Institute Genomics Platform;
RA   Russ C., Tyler B., Panabieres F., Shan W., Tripathy S., Grunwald N.,
RA   Machado M., Johnson C.S., Arredondo F., Hong C., Coffey M., Young S.K.,
RA   Zeng Q., Gargeya S., Fitzgerald M., Abouelleil A., Alvarado L.,
RA   Chapman S.B., Gainer-Dewar J., Goldberg J., Griggs A., Gujja S., Hansen M.,
RA   Howarth C., Imamovic A., Ireland A., Larimer J., McCowan C., Murphy C.,
RA   Pearson M., Poon T.W., Priest M., Roberts A., Saif S., Shea T., Sykes S.,
RA   Wortman J., Nusbaum C., Birren B.;
RT   "The Genome Sequence of Phytophthora parasitica CHvinca01.";
RL   Submitted (NOV-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the glycosyl hydrolase 30 family.
CC       {ECO:0000256|ARBA:ARBA00005382}.
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DR   EMBL; KI678235; ETL99774.1; -; Genomic_DNA.
DR   AlphaFoldDB; W2LSX0; -.
DR   EnsemblProtists; ETL99774; ETL99774; L917_03419.
DR   VEuPathDB; FungiDB:PPTG_08509; -.
DR   Proteomes; UP000054423; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0004348; F:glucosylceramidase activity; IEA:InterPro.
DR   GO; GO:0006665; P:sphingolipid metabolic process; IEA:InterPro.
DR   CDD; cd00161; RICIN; 1.
DR   Gene3D; 2.80.10.50; -; 1.
DR   Gene3D; 3.20.20.80; Glycosidases; 1.
DR   Gene3D; 2.60.40.1180; Golgi alpha-mannosidase II; 1.
DR   InterPro; IPR033452; GH30_C.
DR   InterPro; IPR001139; Glyco_hydro_30.
DR   InterPro; IPR033453; Glyco_hydro_30_TIM-barrel.
DR   InterPro; IPR013780; Glyco_hydro_b.
DR   InterPro; IPR017853; Glycoside_hydrolase_SF.
DR   InterPro; IPR035992; Ricin_B-like_lectins.
DR   InterPro; IPR000772; Ricin_B_lectin.
DR   PANTHER; PTHR11069; GLUCOSYLCERAMIDASE; 1.
DR   PANTHER; PTHR11069:SF23; LYSOSOMAL ACID GLUCOSYLCERAMIDASE; 1.
DR   Pfam; PF02055; Glyco_hydro_30; 1.
DR   Pfam; PF17189; Glyco_hydro_30C; 1.
DR   Pfam; PF00652; Ricin_B_lectin; 1.
DR   PRINTS; PR00843; GLHYDRLASE30.
DR   SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR   SUPFAM; SSF50370; Ricin B-like lectins; 1.
DR   PROSITE; PS50231; RICIN_B_LECTIN; 1.
PE   3: Inferred from homology;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Membrane {ECO:0000256|SAM:Phobius}; Signal {ECO:0000256|ARBA:ARBA00022729};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        32..54
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          128..478
FT                   /note="Glycosyl hydrolase family 30 TIM-barrel"
FT                   /evidence="ECO:0000259|Pfam:PF02055"
FT   DOMAIN          527..628
FT                   /note="Ricin B lectin"
FT                   /evidence="ECO:0000259|Pfam:PF00652"
FT   DOMAIN          631..679
FT                   /note="Glycosyl hydrolase family 30 beta sandwich"
FT                   /evidence="ECO:0000259|Pfam:PF17189"
SQ   SEQUENCE   682 AA;  77110 MW;  136DB9CBE611A9B8 CRC64;
     MTTGPTVYGT SSLASDERLS ARATRRRTIL KWSLMGLAIC AVIAVLAVIG IIALPEDAAV
     APVKTTKSTP NSKAAPALDT EVTCVQSSYV ANVTNMMEPI TGLKWTHGAQ PNAKSFIAVD
     VETKYQEIMG FGGAFTEAAA LQFNKLSKEK QEEVLTLYFD KNKGSAYTFG RVPMGSSDFS
     ASSYSFDDVV NDTELQHFDK DVKHDQDVLI PFIKRALKRQ PDLKLFLAPW SPPAWMKRAA
     FNYEPSMLNS AKPIGLKDDV RATWALYFSK FITAYKNHGI DFWGLTPQNE PQAEVPWESC
     MYTAEYQAEF IGNYLGPMLE RDHPELTLMV FDHNRGSVRQ WAEEIYNHPT AAQYVDGMAF
     HWYDDERYMD GVEYHERLND TYFIDPNRFM LATESCNCPD VGHGDLAWFR AQRYGHDIMS
     DLNNYVAGWV DWNLILDHKG GPNHLANNCD APIIMTEDEK DFFIQPMYYF IQHFSKYIPV
     GSRRVKTQVA TRFTQPGDPQ LYVDYPSMLA RCDGSSRQKW RPTDDGKLTV TGTGFCIDLK
     EIPWQGHQGL LVDCRYTQQH WTYETDTGRI RMGDYCISLN HGSTEDGARI STDLCEDDIM
     PHQQWRFDAE DGTMRSLAST TDQCVTAGYA FVQASAFATP ENHKVLVVMN ENTEPADFEL
     QVGGVALETT VPPRAIRTFT WE
//