ID   W2NKH4_PHYPR            Unreviewed;      1327 AA.
AC   W2NKH4;
DT   19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT   19-MAR-2014, sequence version 1.
DT   27-MAR-2024, entry version 33.
DE   RecName: Full=WW domain-containing protein {ECO:0000259|PROSITE:PS50020};
GN   ORFNames=L914_07017 {ECO:0000313|EMBL:ETM48443.1};
OS   Phytophthora parasitica (Potato buckeye rot agent).
OC   Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC   Phytophthora.
OX   NCBI_TaxID=4792 {ECO:0000313|EMBL:ETM48443.1};
RN   [1] {ECO:0000313|EMBL:ETM48443.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=IAC_01/95 {ECO:0000313|EMBL:ETM48443.1};
RG   The Broad Institute Genomics Platform;
RA   Russ C., Tyler B., Panabieres F., Shan W., Tripathy S., Grunwald N.,
RA   Machado M., Johnson C.S., Arredondo F., Hong C., Coffey M., Young S.K.,
RA   Zeng Q., Gargeya S., Fitzgerald M., Abouelleil A., Alvarado L.,
RA   Chapman S.B., Gainer-Dewar J., Goldberg J., Griggs A., Gujja S., Hansen M.,
RA   Howarth C., Imamovic A., Ireland A., Larimer J., McCowan C., Murphy C.,
RA   Pearson M., Poon T.W., Priest M., Roberts A., Saif S., Shea T., Sykes S.,
RA   Wortman J., Nusbaum C., Birren B.;
RT   "The Genome Sequence of Phytophthora parasitica IAC_01/95.";
RL   Submitted (NOV-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
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DR   EMBL; KI692386; ETM48443.1; -; Genomic_DNA.
DR   EnsemblProtists; ETM48443; ETM48443; L914_07017.
DR   VEuPathDB; FungiDB:PPTG_09815; -.
DR   Proteomes; UP000054532; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR   GO; GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.
DR   CDD; cd00201; WW; 2.
DR   Gene3D; 1.20.5.190; -; 5.
DR   Gene3D; 2.20.70.10; -; 2.
DR   InterPro; IPR000048; IQ_motif_EF-hand-BS.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR001202; WW_dom.
DR   InterPro; IPR036020; WW_dom_sf.
DR   PANTHER; PTHR22706:SF1; ABNORMAL SPINDLE-LIKE MICROCEPHALY-ASSOCIATED PROTEIN ISOFORM X1; 1.
DR   PANTHER; PTHR22706; UNCHARACTERIZED; 1.
DR   Pfam; PF00612; IQ; 10.
DR   Pfam; PF00397; WW; 1.
DR   SMART; SM00015; IQ; 19.
DR   SMART; SM00456; WW; 2.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR   SUPFAM; SSF51045; WW domain; 1.
DR   PROSITE; PS50096; IQ; 15.
DR   PROSITE; PS50020; WW_DOMAIN_2; 2.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Cytoplasm {ECO:0000256|ARBA:ARBA00022490}.
FT   DOMAIN          1128..1162
FT                   /note="WW"
FT                   /evidence="ECO:0000259|PROSITE:PS50020"
FT   DOMAIN          1178..1206
FT                   /note="WW"
FT                   /evidence="ECO:0000259|PROSITE:PS50020"
FT   REGION          29..88
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          994..1057
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        51..88
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1327 AA;  154972 MW;  6096A8D08A2DAFB5 CRC64;
     MDRSHIVTSL LRPLATLDRL KSIDAAPVSS WDKEAATRRP QLVQLPSGPV SAPKKLQQQQ
     QQHASPNQRS ATPLQPLPKT SGIRLNRSTT RVTKVPKLSF TKRRGRNAIS NQFSLDGARQ
     VNAGVYLLEN VNTGHRYFGT TWDLQNAAAQ SFHDLQLGVH PHQALSTCFI LYGEAASGIR
     FRVLEQVSPP SSPKPPVYTD QVRAKRRRIK HLLAGREADN NEDGFDVRAM ERKLATRLRF
     HHRKVVRRAA YKIVRRFLVM PILARAWPLW VRAAEGCALV ERTAATVEIQ RVARGYLDRV
     MVDKIRRDRA ARTLQRFMRR CHFTLACRRR ARSRLESKAA RVLQRSMREF VARRKARRRR
     DGVRRWLAAR KLQTHVRRHL ARRLVDRMRL DKRRARAAVD MQRTTRGHLA RLRVQRQRQR
     RIDDKAATDI QKIWRGYSTR TKVTLRSLGA LSTHRLHHCS IDELRDEAAR TIQQAYSRWE
     ARRLREQNEK ATTIRLAYRN YVARKFGWAA VTVMLETAMA NRIQRAGRRW MFQRKLRRVV
     NEFRRDKAAL TIQCCTRQHH ARLKLYRLRK KKKCAQAIRQ IQAFWCGCWM LLNLRERILK
     RKRERAAKRI QATYRAWIAR REYVAIRDLA RRNRAATKMQ CMFRARQARR ELMRRQVVRR
     LGACESCRSQ LATVYHFEAE SELCAACSDE FASLGDAVME TIDVTVYRRI LVPLMSAQRA
     YRAFQTQMRL RFGTCTLCEK HAVRRSCWSC LYGQGFTANV GKRNGKPAMG LTFCRSCDAL
     FHERKQHQRK DIELAYTEDA AAVTIQKYYR RFAQRCTVAD LRLAQQTLAA KRVQVCFRRH
     RQRRITRAIC AAHRRQQVLE AGAALTIQRA VRGYLARCEL LHLKYERDSA IKIQRAFRRY
     QARRVYNAAV VIQSHVRGWL ARRVACILRQ ERQGRQQNAA ACCIQRHVRG FLARRRVWHL
     RQHKAAVRIQ SAWRGYVARC ELHALQLEKQ RRFNEELRTR LSAVAAQIAE CERAAATCIQ
     TEVRGRQARI ELYRRKLQAA RSAREQLRDN AVALEAASAT CIQRHVRERL TAPVSHHRLR
     AQCCARCFLS RRTVKRMRLE KQSAVRIQRA FRYSRAKRRL ARLVDDDTTP ASAWVELFDE
     ASGCVYYYHT ETGESVWERP AEMDTSPEDA TSENVGEWVE YWDENVGTSY FYNVKTGEAT
     WATPAGYQSS NLEDTTTAET WPLNNGGSYY TLQPRSKLES KDAENQKTEV YGDQYAPYGY
     EDQAYYDNNH EEGAYYYYGD GTAYAYPDDE PVDTEYDINY KIYLTQIAQE QQQQQQQDQK
     PNDTKQA
//