ID W2PZF1_PHYPN Unreviewed; 966 AA.
AC W2PZF1;
DT 19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT 19-MAR-2014, sequence version 1.
DT 24-JAN-2024, entry version 30.
DE RecName: Full=AB hydrolase-1 domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=PPTG_14338 {ECO:0000313|EMBL:ETN05649.1};
OS Phytophthora parasitica (strain INRA-310).
OC Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC Phytophthora.
OX NCBI_TaxID=761204 {ECO:0000313|EMBL:ETN05649.1, ECO:0000313|Proteomes:UP000018817};
RN [1] {ECO:0000313|Proteomes:UP000018817}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=INRA-310 {ECO:0000313|Proteomes:UP000018817};
RG The Broad Institute Genome Sequencing Platform;
RA Russ C., Tyler B., Panabieres F., Shan W., Tripathy S., Grunwald N.,
RA Machado M., Young S.K., Zeng Q., Gargeya S., Fitzgerald M., Haas B.,
RA Abouelleil A., Alvarado L., Arachchi H.M., Berlin A., Chapman S.B.,
RA Gearin G., Goldberg J., Griggs A., Gujja S., Hansen M., Heiman D.,
RA Howarth C., Larimer J., Lui A., MacDonald P.J.P., McCowen C.,
RA Montmayeur A., Murphy C., Neiman D., Pearson M., Priest M., Roberts A.,
RA Saif S., Shea T., Sisk P., Stolte C., Sykes S., Wortman J., Nusbaum C.,
RA Birren B.;
RL Submitted (DEC-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ETN05649.1, ECO:0000313|Proteomes:UP000018817}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=INRA-310 {ECO:0000313|EMBL:ETN05649.1,
RC ECO:0000313|Proteomes:UP000018817};
RG The Broad Institute Genomics Platform;
RA Russ C., Tyler B., Panabieres F., Shan W., Tripathy S., Grunwald N.,
RA Machado M., Johnson C.S., Arredondo F., Hong C., Coffey M., Young S.K.,
RA Zeng Q., Gargeya S., Fitzgerald M., Abouelleil A., Alvarado L.,
RA Chapman S.B., Gainer-Dewar J., Goldberg J., Griggs A., Gujja S., Hansen M.,
RA Howarth C., Imamovic A., Ireland A., Larimer J., McCowan C., Murphy C.,
RA Pearson M., Poon T.W., Priest M., Roberts A., Saif S., Shea T., Sykes S.,
RA Wortman J., Nusbaum C., Birren B.;
RT "The Genome Sequence of Phytophthora parasitica INRA-310.";
RL Submitted (NOV-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Lipid droplet {ECO:0000256|ARBA:ARBA00004502}.
CC -!- SIMILARITY: Belongs to the AB hydrolase superfamily. LDAH family.
CC {ECO:0000256|ARBA:ARBA00008300}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; KI669599; ETN05649.1; -; Genomic_DNA.
DR RefSeq; XP_008909171.1; XM_008910923.1.
DR AlphaFoldDB; W2PZF1; -.
DR EnsemblProtists; ETN05649; ETN05649; PPTG_14338.
DR GeneID; 20183636; -.
DR VEuPathDB; FungiDB:PPTG_14338; -.
DR OrthoDB; 5474978at2759; -.
DR Proteomes; UP000018817; Unassembled WGS sequence.
DR GO; GO:0005811; C:lipid droplet; IEA:UniProtKB-SubCell.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0016298; F:lipase activity; IEA:InterPro.
DR GO; GO:0019915; P:lipid storage; IEA:InterPro.
DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR019363; LDAH.
DR PANTHER; PTHR13390; LIPASE; 1.
DR PANTHER; PTHR13390:SF0; LIPID DROPLET-ASSOCIATED HYDROLASE; 1.
DR Pfam; PF10230; LIDHydrolase; 1.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
PE 3: Inferred from homology;
KW Lipid droplet {ECO:0000256|ARBA:ARBA00022677};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000018817};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 53..76
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 88..107
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 119..139
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 151..172
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 184..209
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 215..234
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 433..454
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 607..643
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 607..623
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 966 AA; 109845 MW; AA989A9BA1E71BCF CRC64;
MLFHILARLL WPKWSLFANM WESMQVELHG IYSTARVLQL AKHERTSNWI HDIAILFGIP
LPCVAVTVLI DVFPLADPTD SIDANTMSFV RVYYSFVVFS LVATHLVRTV MPSRSFTVIR
ALLNALVISA ITVCILYGMT RSIGFPLPFS VLTVSPAWTV LTAIFVVVEW AAQIRSNPDT
QQAVITLIKL WICDALMVFI YPAFFYIFTT LSLDGQRAFA LLLPVIKLIM RNLFARVTVH
FSDATPEFVV FHAEVFNSLF MSYCMQKSPS IWTTLQITIA DALLTVVSLR DIESARRGLK
SLERRIDKKK GWGRFHNSAQ NGRYLEQTTL DRASTLLQQN ENQENTRISS TADIVRIASF
CDRVLNDAKA EGEEVDTRKT VVMPKNMDPS SSLAGGMVRA TGVAVHPISN DRTDIGSSNM
SITLRYTCKV RRLLYMAEFL VLLNYVEVFI PLVFSLNTLA TYHLPNRTYY PAFDVILLRD
AGFYVKKNVG VFTDPATGIC PGETISQSVQ QCCILGVLQC PGITTTLRRQ RSTIKSHSQF
SNVKMLAPGF ARYSSPNTSS PSLPDISTMI QTFMTIKEHA QNYNISTPLF ALIAVARIVY
QRHKEQLEQQ RQDRPRYLIA DSDTDDDATD EEGEAKKSHG KLPSPVKEWN VVAEDDTKTL
SLVYYPEEEV REETPEEDME SPLEKVLILV IPGNPGNPYY YLPLMQELVK KHGRRHEIRC
LSHAGHVMPW KNHNRDFTLQ EQIDQKAFYV KQRLREEPTL RLVVIGHSIG SYITLDIAKR
FPQNIAKLVL MQPAIMHIAL SRKGKQFMTM MNNYEFVVML MGVVDYLVPV SLRRWMVRRS
VGSHAEETVR LASLSLVNSC VIQNVLGMAA NEMAEVVELD EELVTRHEDK ILFVYSTVDE
WVPGEFMQEF QLRFVNTQHR VVPNRHAFMM ELDGTRNVTE HISQWIAVIL DEKKETAKAV
LNFLAS
//
