ID W2QWY7_PHYPN Unreviewed; 1540 AA.
AC W2QWY7;
DT 19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT 19-MAR-2014, sequence version 1.
DT 27-MAR-2024, entry version 41.
DE RecName: Full=SEC7 domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=PPTG_05471 {ECO:0000313|EMBL:ETN17737.1};
OS Phytophthora parasitica (strain INRA-310).
OC Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC Phytophthora.
OX NCBI_TaxID=761204 {ECO:0000313|EMBL:ETN17737.1, ECO:0000313|Proteomes:UP000018817};
RN [1] {ECO:0000313|Proteomes:UP000018817}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=INRA-310 {ECO:0000313|Proteomes:UP000018817};
RG The Broad Institute Genome Sequencing Platform;
RA Russ C., Tyler B., Panabieres F., Shan W., Tripathy S., Grunwald N.,
RA Machado M., Young S.K., Zeng Q., Gargeya S., Fitzgerald M., Haas B.,
RA Abouelleil A., Alvarado L., Arachchi H.M., Berlin A., Chapman S.B.,
RA Gearin G., Goldberg J., Griggs A., Gujja S., Hansen M., Heiman D.,
RA Howarth C., Larimer J., Lui A., MacDonald P.J.P., McCowen C.,
RA Montmayeur A., Murphy C., Neiman D., Pearson M., Priest M., Roberts A.,
RA Saif S., Shea T., Sisk P., Stolte C., Sykes S., Wortman J., Nusbaum C.,
RA Birren B.;
RL Submitted (DEC-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ETN17737.1, ECO:0000313|Proteomes:UP000018817}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=INRA-310 {ECO:0000313|EMBL:ETN17737.1,
RC ECO:0000313|Proteomes:UP000018817};
RG The Broad Institute Genomics Platform;
RA Russ C., Tyler B., Panabieres F., Shan W., Tripathy S., Grunwald N.,
RA Machado M., Johnson C.S., Arredondo F., Hong C., Coffey M., Young S.K.,
RA Zeng Q., Gargeya S., Fitzgerald M., Abouelleil A., Alvarado L.,
RA Chapman S.B., Gainer-Dewar J., Goldberg J., Griggs A., Gujja S., Hansen M.,
RA Howarth C., Imamovic A., Ireland A., Larimer J., McCowan C., Murphy C.,
RA Pearson M., Poon T.W., Priest M., Roberts A., Saif S., Shea T., Sykes S.,
RA Wortman J., Nusbaum C., Birren B.;
RT "The Genome Sequence of Phytophthora parasitica INRA-310.";
RL Submitted (NOV-2013) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; KI669567; ETN17737.1; -; Genomic_DNA.
DR RefSeq; XP_008897265.1; XM_008899017.1.
DR STRING; 761204.W2QWY7; -.
DR EnsemblProtists; ETN17737; ETN17737; PPTG_05471.
DR GeneID; 20175514; -.
DR VEuPathDB; FungiDB:PPTG_05471; -.
DR OMA; TLWNHYR; -.
DR OrthoDB; 204547at2759; -.
DR Proteomes; UP000018817; Unassembled WGS sequence.
DR GO; GO:0000813; C:ESCRT I complex; IEA:InterPro.
DR GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:InterPro.
DR GO; GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.
DR CDD; cd00171; Sec7; 1.
DR Gene3D; 1.10.220.20; -; 1.
DR Gene3D; 2.100.10.50; -; 2.
DR Gene3D; 1.10.1000.11; Arf Nucleotide-binding Site Opener,domain 2; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR023341; MABP.
DR InterPro; IPR032691; Mon2/Sec7/BIG1-like_HUS.
DR InterPro; IPR018798; MVB12A/B.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR001849; PH_domain.
DR InterPro; IPR023394; Sec7_C_sf.
DR InterPro; IPR000904; Sec7_dom.
DR InterPro; IPR035999; Sec7_dom_sf.
DR PANTHER; PTHR10663; GUANYL-NUCLEOTIDE EXCHANGE FACTOR; 1.
DR Pfam; PF10240; DUF2464; 1.
DR Pfam; PF00169; PH; 1.
DR Pfam; PF01369; Sec7; 1.
DR Pfam; PF12783; Sec7-like_HUS; 1.
DR SMART; SM00233; PH; 1.
DR SMART; SM00222; Sec7; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR SUPFAM; SSF48425; Sec7 domain; 1.
DR PROSITE; PS51498; MABP; 1.
DR PROSITE; PS50003; PH_DOMAIN; 1.
DR PROSITE; PS50190; SEC7; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000018817}.
FT DOMAIN 160..318
FT /note="MABP"
FT /evidence="ECO:0000259|PROSITE:PS51498"
FT DOMAIN 886..1079
FT /note="SEC7"
FT /evidence="ECO:0000259|PROSITE:PS50190"
FT DOMAIN 1300..1395
FT /note="PH"
FT /evidence="ECO:0000259|PROSITE:PS50003"
FT REGION 15..40
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 372..394
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1435..1540
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 372..391
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1460..1502
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1503..1523
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1526..1540
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1540 AA; 171352 MW; 6EB5EAB06F10B791 CRC64;
MADVVSESQQ SVFGLTMEVT PVNDDPQEVD AEEASGDARV AIEPPVEMLH EAALRSGINS
ILDETTGDDG DLACIREICQ ETLSKRDQVT AAKSIAHRQK RAKENTSVIR DGSEVVNWKA
FSPPKSLPRT ISKPKLNRRP SYDSIPAGES PRWKIIDGNE GPITDITVNF RGDSVPEGFT
KLERSPSGQR ADLNKGGRGS AIYLCHSKDQ SSGKAPISEM IVIFPERGEI VPTDYEVVRR
RGVPANVNSG TQGEKIYLCF KRSTASAIVD LAVIYPKKND TLPYGYMKVD KTPLGHVADL
NSNSGGTEVF LAYKKKVASI SDLHKMWLFA TVTPPQVLER ARSPPLTPST PRKLRHLKSA
FALKATEVRE QKLISAPNSP TADTSPDSPR SKPKQIGWKE TIEYYMYPLL LACHTRQGKA
AEAAVEGLTH CLEEGVFDCP GSELCRLEVV IDAVLSICQQ GVKSRFEPAL KFFQKVIRMS
TDGFDPFVLH AILKALIFIG DFDGPLTKSI EDELISKIMV AYEATLTTTI VKKNDAKVDQ
SSTALAHALV VDLIDDISTG AEIATATDNM LGVFKSHLSI QSPSFSQDIS AAMTNFANSA
AEKNALQLVV TFSKAINRKF VSLSETATES DQCSSVTSLR VLNQTLLAAG TRTREQRVFG
QVVRRFVLST LNATVLTWAP NVFRAILTLV TTLWNHYRRY LKVELALMFE HVFLRILRAT
APCTKDHQLE IMHEMTNWLQ LPHNVVEIFL NFDLDRIQQW KIFEHLCSTL GSIGEGNVSH
LANGDEGDDS GLELQNQAIN TILAMARSVM DASGHAHLIS RDRRTRMLSM YTGGWEQDES
GEEVSPMKDA FGMLPSGDVA SQPGSPAEQK RQANRKYGGN ISVRMRNELQ KHNQQLLKRA
MEISSSKSLK KALEYLVAMN FIKDTPRSIT SFLRIYHDFF DETEIGDYLG EGDEDFKVQV
RLTYVRAISF KGMTLVESLR HFLTNGGFRL PGEAQKIERM VEAFAQCYWD DSRTAFSSAD
TAMIIAYSII MLNTDLHNPQ VKKNKMSKEQ FVKNNRGIDN GNDLPKRFLE EIYDDIAHNP
MHIKGSRVIP KASREASVSA ADLENEKFRG GIAKAVAQSE ELMKDLSHTY NTFQFVGVDT
AISPDLIKIL FERVWFSLLT LSTTILCDSQ SDLSTRMQCL DLLRFCISTC LFLNMPVERQ
AFCSLLRKVQ DSLDGTPQEN SEEELADKAT KAIPQDTKYE WARTIEAAAG SDDPWKAMGD
IHLLVNDMKE TIQVRQKSEK LDSVIQRIHR AHFYLKNSTT FIHEGDLTKK CRSRNQLYRF
FLFNDQLLYA DKSMTGKWSP HNSLRLKLTR ISTIADGVLL KNAFQIQNPV KSFVVFADSA
TSKAEWMRLI DDAIAEASKK MNRTARRIST QVLSDTRPSL VTSSAMKVFL RFSSPMPSPV
ARDHRQASFD SDGESPVKPV EVNESSSTQN TTSAVENKIL SNTDVQDPTA VATVTSGDSA
QPNSKEDELK RAAIDDKGVD MHPESASPKS SVTSSKATLQ
//
