ID W2R3V6_PHYPN Unreviewed; 246 AA.
AC W2R3V6;
DT 19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT 19-MAR-2014, sequence version 1.
DT 24-JAN-2024, entry version 30.
DE RecName: Full=Dynein attachment factor N-terminal domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=PPTG_04706 {ECO:0000313|EMBL:ETN19364.1};
OS Phytophthora parasitica (strain INRA-310).
OC Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC Phytophthora.
OX NCBI_TaxID=761204 {ECO:0000313|EMBL:ETN19364.1, ECO:0000313|Proteomes:UP000018817};
RN [1] {ECO:0000313|Proteomes:UP000018817}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=INRA-310 {ECO:0000313|Proteomes:UP000018817};
RG The Broad Institute Genome Sequencing Platform;
RA Russ C., Tyler B., Panabieres F., Shan W., Tripathy S., Grunwald N.,
RA Machado M., Young S.K., Zeng Q., Gargeya S., Fitzgerald M., Haas B.,
RA Abouelleil A., Alvarado L., Arachchi H.M., Berlin A., Chapman S.B.,
RA Gearin G., Goldberg J., Griggs A., Gujja S., Hansen M., Heiman D.,
RA Howarth C., Larimer J., Lui A., MacDonald P.J.P., McCowen C.,
RA Montmayeur A., Murphy C., Neiman D., Pearson M., Priest M., Roberts A.,
RA Saif S., Shea T., Sisk P., Stolte C., Sykes S., Wortman J., Nusbaum C.,
RA Birren B.;
RL Submitted (DEC-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ETN19364.1, ECO:0000313|Proteomes:UP000018817}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=INRA-310 {ECO:0000313|EMBL:ETN19364.1,
RC ECO:0000313|Proteomes:UP000018817};
RG The Broad Institute Genomics Platform;
RA Russ C., Tyler B., Panabieres F., Shan W., Tripathy S., Grunwald N.,
RA Machado M., Johnson C.S., Arredondo F., Hong C., Coffey M., Young S.K.,
RA Zeng Q., Gargeya S., Fitzgerald M., Abouelleil A., Alvarado L.,
RA Chapman S.B., Gainer-Dewar J., Goldberg J., Griggs A., Gujja S., Hansen M.,
RA Howarth C., Imamovic A., Ireland A., Larimer J., McCowan C., Murphy C.,
RA Pearson M., Poon T.W., Priest M., Roberts A., Saif S., Shea T., Sykes S.,
RA Wortman J., Nusbaum C., Birren B.;
RT "The Genome Sequence of Phytophthora parasitica INRA-310.";
RL Submitted (NOV-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Dynein-attachment factor required for cilia motility.
CC {ECO:0000256|ARBA:ARBA00004048}.
CC -!- SUBUNIT: Homodimer. {ECO:0000256|ARBA:ARBA00011738}.
CC -!- SUBCELLULAR LOCATION: Cell projection, cilium, flagellum
CC {ECO:0000256|ARBA:ARBA00004230}. Cytoplasm
CC {ECO:0000256|ARBA:ARBA00004496}.
CC -!- SIMILARITY: Belongs to the CCDC103/PR46b family.
CC {ECO:0000256|ARBA:ARBA00008470}.
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DR EMBL; KI669565; ETN19364.1; -; Genomic_DNA.
DR RefSeq; XP_008895221.1; XM_008896973.1.
DR AlphaFoldDB; W2R3V6; -.
DR STRING; 761204.W2R3V6; -.
DR EnsemblProtists; ETN19364; ETN19364; PPTG_04706.
DR GeneID; 20174788; -.
DR VEuPathDB; FungiDB:PPTG_04706; -.
DR OMA; YRNWRRH; -.
DR OrthoDB; 54328at2759; -.
DR Proteomes; UP000018817; Unassembled WGS sequence.
DR GO; GO:0031514; C:motile cilium; IEA:UniProtKB-SubCell.
DR GO; GO:0036157; C:outer dynein arm; IEA:InterPro.
DR GO; GO:0070286; P:axonemal dynein complex assembly; IEA:InterPro.
DR InterPro; IPR042422; CC103.
DR InterPro; IPR031733; Dynein_attach_N.
DR InterPro; IPR025986; RPAP3-like_C.
DR PANTHER; PTHR28572; COILED-COIL DOMAIN-CONTAINING PROTEIN 103; 1.
DR PANTHER; PTHR28572:SF1; COILED-COIL DOMAIN-CONTAINING PROTEIN 103; 1.
DR Pfam; PF15867; Dynein_attach_N; 1.
DR Pfam; PF13877; RPAP3_C; 1.
PE 3: Inferred from homology;
KW Cell projection {ECO:0000256|ARBA:ARBA00023273};
KW Cilium {ECO:0000256|ARBA:ARBA00023069};
KW Cilium biogenesis/degradation {ECO:0000256|ARBA:ARBA00022794};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Flagellum {ECO:0000256|ARBA:ARBA00022846};
KW Reference proteome {ECO:0000313|Proteomes:UP000018817}.
FT DOMAIN 18..84
FT /note="Dynein attachment factor N-terminal"
FT /evidence="ECO:0000259|Pfam:PF15867"
FT DOMAIN 112..210
FT /note="RNA-polymerase II-associated protein 3-like C-
FT terminal"
FT /evidence="ECO:0000259|Pfam:PF13877"
FT REGION 74..110
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 74..97
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 246 AA; 28024 MW; 1BA8B4C01E8F7998 CRC64;
MVKKTADQLT SIEHGAFDTA ALQQELAQAL EDDRLYKLTD SMKKRAIHTA ANYDDFKNLV
ACADLKPISQ KELRDFSRTE RQTNISYKKK PTQKKSGNDR RSQPAAPALD VPPATAVDFC
RNWKRYLKTT DAKFRYLQLT TPERLADMFK PDIDSDLMAD IVEVLVASWT QKPADINPED
PAPPTFALAV MEALSQTTRL SLILDFFEDH QMEKVHELFN LVETADDLSE QDLEMLPSLK
EKFRLG
//
