ID W2R9U5_PHYPN Unreviewed; 569 AA.
AC W2R9U5;
DT 19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT 19-MAR-2014, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE RecName: Full=Major facilitator superfamily (MFS) profile domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=PPTG_01515 {ECO:0000313|EMBL:ETN21280.1};
OS Phytophthora parasitica (strain INRA-310).
OC Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC Phytophthora.
OX NCBI_TaxID=761204 {ECO:0000313|EMBL:ETN21280.1, ECO:0000313|Proteomes:UP000018817};
RN [1] {ECO:0000313|Proteomes:UP000018817}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=INRA-310 {ECO:0000313|Proteomes:UP000018817};
RG The Broad Institute Genome Sequencing Platform;
RA Russ C., Tyler B., Panabieres F., Shan W., Tripathy S., Grunwald N.,
RA Machado M., Young S.K., Zeng Q., Gargeya S., Fitzgerald M., Haas B.,
RA Abouelleil A., Alvarado L., Arachchi H.M., Berlin A., Chapman S.B.,
RA Gearin G., Goldberg J., Griggs A., Gujja S., Hansen M., Heiman D.,
RA Howarth C., Larimer J., Lui A., MacDonald P.J.P., McCowen C.,
RA Montmayeur A., Murphy C., Neiman D., Pearson M., Priest M., Roberts A.,
RA Saif S., Shea T., Sisk P., Stolte C., Sykes S., Wortman J., Nusbaum C.,
RA Birren B.;
RL Submitted (DEC-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ETN21280.1, ECO:0000313|Proteomes:UP000018817}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=INRA-310 {ECO:0000313|EMBL:ETN21280.1,
RC ECO:0000313|Proteomes:UP000018817};
RG The Broad Institute Genomics Platform;
RA Russ C., Tyler B., Panabieres F., Shan W., Tripathy S., Grunwald N.,
RA Machado M., Johnson C.S., Arredondo F., Hong C., Coffey M., Young S.K.,
RA Zeng Q., Gargeya S., Fitzgerald M., Abouelleil A., Alvarado L.,
RA Chapman S.B., Gainer-Dewar J., Goldberg J., Griggs A., Gujja S., Hansen M.,
RA Howarth C., Imamovic A., Ireland A., Larimer J., McCowan C., Murphy C.,
RA Pearson M., Poon T.W., Priest M., Roberts A., Saif S., Shea T., Sykes S.,
RA Wortman J., Nusbaum C., Birren B.;
RT "The Genome Sequence of Phytophthora parasitica INRA-310.";
RL Submitted (NOV-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the major facilitator superfamily. Folate-
CC biopterin transporter (TC 2.A.71) family.
CC {ECO:0000256|ARBA:ARBA00007015}.
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DR EMBL; KI669563; ETN21280.1; -; Genomic_DNA.
DR RefSeq; XP_008893088.1; XM_008894840.1.
DR AlphaFoldDB; W2R9U5; -.
DR EnsemblProtists; ETN21280; ETN21280; PPTG_01515.
DR GeneID; 20171804; -.
DR VEuPathDB; FungiDB:PPTG_01515; -.
DR OMA; IITMCGA; -.
DR OrthoDB; 71141at2759; -.
DR Proteomes; UP000018817; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR InterPro; IPR039309; BT1.
DR InterPro; IPR036259; MFS_trans_sf.
DR PANTHER; PTHR31585; FOLATE-BIOPTERIN TRANSPORTER 1, CHLOROPLASTIC; 1.
DR PANTHER; PTHR31585:SF5; RIBOSOMAL_L9 DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF03092; BT1; 2.
DR SUPFAM; SSF103473; MFS general substrate transporter; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000018817};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 64..85
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 91..112
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 133..153
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 190..208
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 229..249
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 269..287
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 348..367
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 379..401
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 490..509
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 530..550
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 569 AA; 63322 MW; C2AE4FE0DB99B280 CRC64;
MTLTDDTVKA VLEDRPSRLS DLKPTQSETA YSNLASPGKP GNIELENGAL REGKPLQLLS
KECIGLLAQY AGVGFLAGVI PGVIYPVLQG YLNAEGTIVV SATVLVQIPW CYKMFFGVIS
DCFPIMGYRR RPYMVIGWVF CVTILIIMAA MSIPDPYYGD PAMHSIDEVD WTDDQIDSIN
ANAPNSAGKY VVPMMLASFG YLLCEVAADA MVVEYAQREP IEQRGRVQTA VYAVKTSFTA
VGAAVIAFFM NGEEYAGSFD FSLTFQQLML ISGIICAPLV FVSWFLLHED RVKDKPTFGE
YMSSFWGMLQ QRAIYQIVAY KFFSGVFNSF NIVSSSNIKL YWVHATPFNN SVMTIVGTIF
YATTLALTGK YGLDWNWRYI IIITMCGALS IDAFMTMLTV WDVVRNQWFW LGVPVIEYLP
DGIRFMIATY VVVELAEAGH EGALYGLLTA TTNLTTPFGR SMAKLVNAQF HVWLKDIQAD
TYVVRRDVTI TIWICYGMKL LSLAFLPLLP RQKAETQELK RTGGSSRIMG IITVGYLAFA
IVWATLVNLL SMYETTMCWK ITGGCAPSS
//
