ID W2RHC9_PHYPN Unreviewed; 2696 AA.
AC W2RHC9;
DT 19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT 19-MAR-2014, sequence version 1.
DT 27-MAR-2024, entry version 46.
DE RecName: Full=Dynein heavy chain {ECO:0008006|Google:ProtNLM};
GN ORFNames=PPTG_00868 {ECO:0000313|EMBL:ETN24636.1};
OS Phytophthora parasitica (strain INRA-310).
OC Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC Phytophthora.
OX NCBI_TaxID=761204 {ECO:0000313|EMBL:ETN24636.1, ECO:0000313|Proteomes:UP000018817};
RN [1] {ECO:0000313|Proteomes:UP000018817}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=INRA-310 {ECO:0000313|Proteomes:UP000018817};
RG The Broad Institute Genome Sequencing Platform;
RA Russ C., Tyler B., Panabieres F., Shan W., Tripathy S., Grunwald N.,
RA Machado M., Young S.K., Zeng Q., Gargeya S., Fitzgerald M., Haas B.,
RA Abouelleil A., Alvarado L., Arachchi H.M., Berlin A., Chapman S.B.,
RA Gearin G., Goldberg J., Griggs A., Gujja S., Hansen M., Heiman D.,
RA Howarth C., Larimer J., Lui A., MacDonald P.J.P., McCowen C.,
RA Montmayeur A., Murphy C., Neiman D., Pearson M., Priest M., Roberts A.,
RA Saif S., Shea T., Sisk P., Stolte C., Sykes S., Wortman J., Nusbaum C.,
RA Birren B.;
RL Submitted (DEC-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ETN24636.1, ECO:0000313|Proteomes:UP000018817}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=INRA-310 {ECO:0000313|EMBL:ETN24636.1,
RC ECO:0000313|Proteomes:UP000018817};
RG The Broad Institute Genomics Platform;
RA Russ C., Tyler B., Panabieres F., Shan W., Tripathy S., Grunwald N.,
RA Machado M., Johnson C.S., Arredondo F., Hong C., Coffey M., Young S.K.,
RA Zeng Q., Gargeya S., Fitzgerald M., Abouelleil A., Alvarado L.,
RA Chapman S.B., Gainer-Dewar J., Goldberg J., Griggs A., Gujja S., Hansen M.,
RA Howarth C., Imamovic A., Ireland A., Larimer J., McCowan C., Murphy C.,
RA Pearson M., Poon T.W., Priest M., Roberts A., Saif S., Shea T., Sykes S.,
RA Wortman J., Nusbaum C., Birren B.;
RT "The Genome Sequence of Phytophthora parasitica INRA-310.";
RL Submitted (NOV-2013) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; KI669561; ETN24636.1; -; Genomic_DNA.
DR RefSeq; XP_008890689.1; XM_008892441.1.
DR STRING; 761204.W2RHC9; -.
DR EnsemblProtists; ETN24636; ETN24636; PPTG_00868.
DR GeneID; 20171211; -.
DR VEuPathDB; FungiDB:PPTG_00868; -.
DR OrthoDB; 312149at2759; -.
DR Proteomes; UP000018817; Unassembled WGS sequence.
DR GO; GO:0030286; C:dynein complex; IEA:InterPro.
DR GO; GO:0045505; F:dynein intermediate chain binding; IEA:InterPro.
DR GO; GO:0051959; F:dynein light intermediate chain binding; IEA:InterPro.
DR GO; GO:0008569; F:minus-end-directed microtubule motor activity; IEA:InterPro.
DR GO; GO:0007018; P:microtubule-based movement; IEA:InterPro.
DR Gene3D; 1.10.287.2620; -; 1.
DR Gene3D; 1.10.472.130; -; 1.
DR Gene3D; 1.10.8.1220; -; 1.
DR Gene3D; 1.20.920.30; -; 1.
DR Gene3D; 6.10.140.1060; -; 1.
DR Gene3D; 1.20.140.100; Dynein heavy chain, N-terminal domain 2; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 4.
DR Gene3D; 1.10.8.720; Region D6 of dynein motor; 1.
DR InterPro; IPR041658; AAA_lid_11.
DR InterPro; IPR042219; AAA_lid_11_sf.
DR InterPro; IPR026983; DHC_fam.
DR InterPro; IPR041589; DNAH3_AAA_lid_1.
DR InterPro; IPR042222; Dynein_2_N.
DR InterPro; IPR041466; Dynein_AAA5_ext.
DR InterPro; IPR024317; Dynein_heavy_chain_D4_dom.
DR InterPro; IPR004273; Dynein_heavy_D6_P-loop.
DR InterPro; IPR013602; Dynein_heavy_linker.
DR InterPro; IPR013594; Dynein_heavy_tail.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR10676:SF343; DYNEIN AXONEMAL HEAVY CHAIN 10; 1.
DR PANTHER; PTHR10676; DYNEIN HEAVY CHAIN FAMILY PROTEIN; 1.
DR Pfam; PF12775; AAA_7; 1.
DR Pfam; PF12780; AAA_8; 1.
DR Pfam; PF17857; AAA_lid_1; 1.
DR Pfam; PF18198; AAA_lid_11; 1.
DR Pfam; PF08385; DHC_N1; 1.
DR Pfam; PF08393; DHC_N2; 1.
DR Pfam; PF17852; Dynein_AAA_lid; 1.
DR Pfam; PF03028; Dynein_heavy; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000018817}.
FT DOMAIN 291..638
FT /note="Dynein heavy chain tail"
FT /evidence="ECO:0000259|Pfam:PF08385"
FT DOMAIN 1139..1513
FT /note="Dynein heavy chain linker"
FT /evidence="ECO:0000259|Pfam:PF08393"
FT DOMAIN 1613..1736
FT /note="Dynein heavy chain AAA 5 extension"
FT /evidence="ECO:0000259|Pfam:PF17852"
FT DOMAIN 1968..2045
FT /note="Dynein heavy chain 3 AAA+ lid"
FT /evidence="ECO:0000259|Pfam:PF17857"
FT DOMAIN 2106..2147
FT /note="Dynein heavy chain AAA module D4"
FT /evidence="ECO:0000259|Pfam:PF12780"
FT DOMAIN 2421..2533
FT /note="Dynein heavy chain region D6 P-loop"
FT /evidence="ECO:0000259|Pfam:PF03028"
FT DOMAIN 2564..2681
FT /note="Dynein heavy chain AAA lid"
FT /evidence="ECO:0000259|Pfam:PF18198"
FT REGION 76..102
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 209..230
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 959..993
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 210..230
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2696 AA; 306918 MW; 949BF77C65662683 CRC64;
MSLDEVTRRW LQRLVSRALD VEPSAVDQLL VVSKTADSTE EHSAAELVQS FFSPKAAAGS
ILFFYKGEEQ YELEEEVEEE VEVTREATPT DPPSDGLSSA EPTDEQLFLD AEAPTPQTET
VKRLVKRSRS AKRSVCHAFL NTLPAESSES ASVFLIKVAA GPITVQNVVT DGHEKVVHSN
VELGCSTGDL LSNLEGVICN VFMPLLDPQL TRPDNSNGRP EGDENGAKNS TAAHQALKVI
DAVRNEFKSN LVKFSSQISN AIQQIQGDIH LNIPDVVITK PESHLDDYEL INRLEQALEE
WSKSVASVVE QEIRKTPKRK GPLAEIEFWR ERNATLSTIF EQINMPTVQK MLKLLELVEA
SMLLTFKYHF SELSKLYVEA KDNVKFLTTL ERHFKNIASG SFSAIADTLP SMMNAIRMVW
IISRHYNTDE RMVPLMERIA SEIVDKVAVE INIHTILRKS PDNALHAIEE AKMVLELWHS
TYMKVRERIE ASGTDHRWEF DRKRLFEQTN YMAKICENLQ EVATVLDQFN KFLGPELKSV
TGDSQGIDEV MARVESLIAP FESVPFKIFD RGYKTSWESV MVQFRDKVSE IEQMTRKFID
TSFQKLRSAE GAFDLLQNFQ NIQSRDSINK QMMENQIHKS SKMVEEIVMD IESTLLIKIE
DFGEGVVTEV GEFYELVERN RMQRIEELVQ SYRSIGPLLI KVEEIVAGVN TGASPKMSTY
YMYWERRIFN AITKMIIASM TTFQALLNVH TKDISSAISI MGQGEGGKLK RPPLCKVKAT
MNGKDIIVTP SLSDMYKYLS KSVKHIVESA KAFIRWMHGT CRETAPLVVN EDEEPITFTF
YSDISQNPYV IKMTLSLNQE IHKVFNIVNR YLDSWRRYDT VYNLWNTKRR SALEKLADKK
PPCVYFDTRM AQYTRLAESV RNQPTEKDTD FLQINCLPLA ISIAKQAEMW KDDYGKILLE
VSNKKLVAIS NTMDQLETEL ESIPEDLESL KKVLNTVASI SDMGMEMELE YADIIERYRT
LQTFNIAGDP AEFKKAFSLE QRWKDLYIAS KTKDLRLVKV KDQFRGVTKQ DAVNFAEECK
DMKKEFLERG PGTCSLDLDA GLELVSVFKK KLAVFKSRRQ ELANAENLFS LPITSYPELQ
QITEALEKQE VIYDLYTEQK EFISNFSSML WAELDVTAMN KGIEELEKRC RKIPKDLKAM
STFVEVEKQI LSFKESIPLI QSLKNEAVKP RHWEELMAVT QVRFDMNLKT FTLGNLFAMK
LHRFSNEIGE IVNAATQEQK IEQEIIKIED SWSKAVLELV KYKKNGTDRG WVLRAADELK
ITLEDHMLNL QTMSGSRFIA SFAERVRKWE KRLGVVNECL DIWFVVQRKW MYLESIFVGA
EDIRQQLPEE AKKFDAIDKA WKTIMGATYK NANAVEACTA ENRVETLHSL SERLDKCQKS
LSDYLDTKRN SFPRFFFISD DELLSVLGSS DPTSIQVHML KLFDNVKLLG FVRNNKNVGA
MESAEGEGFQ FRTLVMDDNK LLTLPNGERI RLQTHCCMIC ETFDLQYASP ATISRCGMVW
VDPKNLGYRP YYERWLKKKY PMVAVTASTD TPPSVISPPP GTLVTPLERI LLLELFDKYV
PKCIDFILDG VFSKDEVVAK CQQVIPISNM EMCKQLCISL DAFLPSDGSL DPTTDRASVE
GIFLFSVVWS LGAALLGSSR ARFNEFIRKI ADCPLPATSL YYNFFDLETR KWQPWESRVV
SYTEPAPFNF SRVFVPTTDS VLYSFILASC MRTEKPILFV GESGTAKTVT IQSYLAGLDQ
QTCSTLSINF SSRTSSLDVQ TNIQANVDKR SGKIYGPPAG KKLLIFIDDL NMPKVDLYGT
QQPIALLHFV MNRGSMYDRG KELDLRILKD LLFIGAMGPP GGGRNQVDPR FVAQFNVYNL
TPPTKEVLKH IYGSIVTTYL RNFSEEIQAK GIKLTEALLQ FFEFTLEKLP PTPSKFHYIF
NLRDLGRVCE GICMATTDKF DTSGKIVRLW RNEVKRIFCD RLTSESDNAL VDGAITQILR
DTFPDETEVA SADPLIFGDY ADCIGRITGQ ASTEDARLYQ DMESYRRIRG IFDEALETYN
LDNKPMTLVL FEMALEHLSR ILRIIRNPLG HALLIGVGGS GKQSLSSGNI LDNEELIATL
DETKNKATEI SAKLELASFT KDEITKAREV YTPVALRGSI MYFAMAALAT IMKMYEISLA
SFLTVFHTAL ETAKRDVVLE KRLRFMVQSI TEMMYDYTCT GIFERHKLMF SFQMTCMIMS
ASGELSRAEL DFFLKGDTSL DAASQPKPED LTWVSGAGWK DLLCLSKLGE EGGVFASLMS
DFKTKTSEWK AWYDLEAPEL ADLPCGYSDK LSSLQKLLVF RCFRQDRVYN AMKLFVIATM
SEKFVQPPVL DYARIYSQSA ATSPIVCILS PGADPQSDIQ TLGDEYGFSG HRFKFLALGQ
GQGPLAEQML EAGASRGHWV LLQNCHLLAS WLRTLEKMLL AMTKPHKDFR LWLTTEPTDR
FPLGILQRSL KVVTEPPDGL KQNMRSLYSK LDQTMLDECP HPAFRSVVYV LCFLHAVVLE
RRKYGKIGWN VSYDFNESDF TISRKLLSLY LYKAYEDQDE QLPWGSLKYL IGDAMYGGRV
SDDYDRRILT TYLSEYMGDF LFDDCQRFYF SRSGFDYVLP GALNASVSSI WCRSLA
//
