ID   W2S6A7_9EURO            Unreviewed;       660 AA.
AC   W2S6A7;
DT   19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT   19-MAR-2014, sequence version 1.
DT   24-JAN-2024, entry version 35.
DE   RecName: Full=HOOK N-terminal domain-containing protein {ECO:0000259|Pfam:PF19047};
GN   ORFNames=HMPREF1541_10792 {ECO:0000313|EMBL:ETN44241.1};
OS   Cyphellophora europaea CBS 101466.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Chaetothyriomycetidae; Chaetothyriales; Cyphellophoraceae; Cyphellophora.
OX   NCBI_TaxID=1220924 {ECO:0000313|EMBL:ETN44241.1, ECO:0000313|Proteomes:UP000030752};
RN   [1] {ECO:0000313|EMBL:ETN44241.1, ECO:0000313|Proteomes:UP000030752}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CBS 101466 {ECO:0000313|EMBL:ETN44241.1,
RC   ECO:0000313|Proteomes:UP000030752};
RG   The Broad Institute Genomics Platform;
RA   Cuomo C., de Hoog S., Gorbushina A., Walker B., Young S.K., Zeng Q.,
RA   Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA   Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA   Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA   Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA   Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA   Birren B.;
RT   "The Genome Sequence of Phialophora europaea CBS 101466.";
RL   Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; KI635846; ETN44241.1; -; Genomic_DNA.
DR   RefSeq; XP_008713683.1; XM_008715461.1.
DR   AlphaFoldDB; W2S6A7; -.
DR   STRING; 1220924.W2S6A7; -.
DR   GeneID; 19978131; -.
DR   VEuPathDB; FungiDB:HMPREF1541_10792; -.
DR   eggNOG; ENOG502QQM8; Eukaryota.
DR   HOGENOM; CLU_406542_0_0_1; -.
DR   InParanoid; W2S6A7; -.
DR   OrthoDB; 2671295at2759; -.
DR   Proteomes; UP000030752; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR   GO; GO:0030705; P:cytoskeleton-dependent intracellular transport; IEA:InterPro.
DR   CDD; cd22211; HkD_SF; 1.
DR   Gene3D; 1.10.418.10; Calponin-like domain; 1.
DR   InterPro; IPR036872; CH_dom_sf.
DR   InterPro; IPR043936; HOOK_N.
DR   PANTHER; PTHR18947:SF28; GIRDIN, ISOFORM A; 1.
DR   PANTHER; PTHR18947; HOOK PROTEINS; 1.
DR   Pfam; PF19047; HOOK_N; 1.
DR   SUPFAM; SSF116907; Hook domain; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW   Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW   Reference proteome {ECO:0000313|Proteomes:UP000030752}.
FT   DOMAIN          10..149
FT                   /note="HOOK N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF19047"
FT   REGION          149..184
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          424..530
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          556..596
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          200..379
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        166..184
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        455..472
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        562..577
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   660 AA;  74272 MW;  A8FC7FF18D286582 CRC64;
     MATVEDTAAG LIAWLNNLDV ADDVQTASDL NDGTVIWKAL QRIDALSFPG KLPEAPNAEQ
     WIPRWNNLKR INDALNMFLA EDCGQRLPLP SGAPDLKAIA QNASLHDTVA LLKLIVVAAI
     NCNDRIDFLT RMQELDTATQ EVLMRTAQEA SEIEEAPEDE GPEPEHTQEL EPKSSPDPRS
     PRLDNDFAAE ERLGRVLADN QRIAHEKRDV ERQLDDAYAR YERLQDTLDK SQDELKETND
     RLTAVLAGRA EGTHRDAKNE TIIAQLESRV SAADNELEEL RKSNELLKIR VEKTQKLQDD
     YDEMKIERDK LARKANAAEK YKQKLEASQD LEKENQNLRE RVTELQGQVR FSDSTTMAKS
     DLQRENEELK KLFSVIEQDY NETADMKKRL EFDYQTLEAR FHDRGEDLRR HQQTIEDLQG
     RLADFDEGVQ LPPVTVSDTA KVLEDDEAEG EQDEQDEKDA AKADKEEGFA DSESRLTAAL
     INGESDKGEE GISEDELRAI VSAMRAQAQA GTATERESST KAQKKLVVGL ERSRTRNSEL
     LEHIKKQSDL IKNLQTQAPA ATVEKREEER PPTPPPKDEE SRAPSPTPSE ADTNLEAAGK
     VIKNLQRELN LITSAWYEQN KRIASSGMAT LRTRASPEPK SFLGRQRRTV DVIALGGTAR
//