ID W2S7A5_9EURO Unreviewed; 429 AA.
AC W2S7A5;
DT 19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT 19-MAR-2014, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE RecName: Full=Calcineurin-like phosphoesterase domain-containing protein {ECO:0000259|Pfam:PF00149};
GN ORFNames=HMPREF1541_10261 {ECO:0000313|EMBL:ETN44591.1};
OS Cyphellophora europaea CBS 101466.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Chaetothyriomycetidae; Chaetothyriales; Cyphellophoraceae; Cyphellophora.
OX NCBI_TaxID=1220924 {ECO:0000313|EMBL:ETN44591.1, ECO:0000313|Proteomes:UP000030752};
RN [1] {ECO:0000313|EMBL:ETN44591.1, ECO:0000313|Proteomes:UP000030752}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 101466 {ECO:0000313|EMBL:ETN44591.1,
RC ECO:0000313|Proteomes:UP000030752};
RG The Broad Institute Genomics Platform;
RA Cuomo C., de Hoog S., Gorbushina A., Walker B., Young S.K., Zeng Q.,
RA Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Phialophora europaea CBS 101466.";
RL Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; KB822714; ETN44591.1; -; Genomic_DNA.
DR RefSeq; XP_008713154.1; XM_008714932.1.
DR AlphaFoldDB; W2S7A5; -.
DR STRING; 1220924.W2S7A5; -.
DR GeneID; 19977600; -.
DR VEuPathDB; FungiDB:HMPREF1541_10261; -.
DR eggNOG; KOG0371; Eukaryota.
DR HOGENOM; CLU_023125_0_0_1; -.
DR InParanoid; W2S7A5; -.
DR OrthoDB; 1353at2759; -.
DR Proteomes; UP000030752; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR CDD; cd00144; MPP_PPP_family; 1.
DR Gene3D; 3.60.21.10; -; 1.
DR InterPro; IPR004843; Calcineurin-like_PHP_ApaH.
DR InterPro; IPR029052; Metallo-depent_PP-like.
DR PANTHER; PTHR42850; METALLOPHOSPHOESTERASE; 1.
DR PANTHER; PTHR42850:SF4; METALLOPHOSPHOESTERASE YNL217W-RELATED; 1.
DR Pfam; PF00149; Metallophos; 1.
DR SUPFAM; SSF56300; Metallo-dependent phosphatases; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000030752};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 75..98
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 153..333
FT /note="Calcineurin-like phosphoesterase"
FT /evidence="ECO:0000259|Pfam:PF00149"
SQ SEQUENCE 429 AA; 47778 MW; 1DE09CE43F9DDDB5 CRC64;
MVSEKPRQQD EGPFTVASSG VHSRKTLVEY CTNEWQTPSA NGADSELWYD KYLDRLDEYY
DACLAVAKAP KFRRLVLSAL TAALFTWLLW TRVLWPWLEE ERAAWDTFHT FSESTSQPLF
GTNSRPHLGG LIQTKDLDSS LLPGAPNADK SRRLIFIGDI HGCKKELLEL LHKVKFNEAT
DHIISVGDIV TKGPDSLGVI DILRERKASV VRGNHDDRVI LLAERKRRHA RGEGVEDADS
VGIETRGKGK LKHKSADAVA GALSDEQLQY LKSFPLILKV GSIKGIGEMV AVHGGLVPGI
PLESQDPVSV MNMRSIDLKT HVPSKLHHDK HKGSKPWFKI WGKYQRLLPA MEKWSAPKTG
KPGKGTGQLT IIYGHDARMG LQISRFSKGL DTNCARAGQL TALVVHETGK EELVQQQCYK
DYTSLGDEE
//
