ID W2S7Q6_9EURO Unreviewed; 595 AA.
AC W2S7Q6;
DT 19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT 19-MAR-2014, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE RecName: Full=FAD-dependent oxidoreductase 2 FAD binding domain-containing protein {ECO:0000259|Pfam:PF00890};
GN ORFNames=HMPREF1541_10335 {ECO:0000313|EMBL:ETN44665.1};
OS Cyphellophora europaea CBS 101466.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Chaetothyriomycetidae; Chaetothyriales; Cyphellophoraceae; Cyphellophora.
OX NCBI_TaxID=1220924 {ECO:0000313|EMBL:ETN44665.1, ECO:0000313|Proteomes:UP000030752};
RN [1] {ECO:0000313|EMBL:ETN44665.1, ECO:0000313|Proteomes:UP000030752}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 101466 {ECO:0000313|EMBL:ETN44665.1,
RC ECO:0000313|Proteomes:UP000030752};
RG The Broad Institute Genomics Platform;
RA Cuomo C., de Hoog S., Gorbushina A., Walker B., Young S.K., Zeng Q.,
RA Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Phialophora europaea CBS 101466.";
RL Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=FAD; Xref=ChEBI:CHEBI:57692;
CC Evidence={ECO:0000256|ARBA:ARBA00001974};
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; KB822714; ETN44665.1; -; Genomic_DNA.
DR RefSeq; XP_008713228.1; XM_008715006.1.
DR AlphaFoldDB; W2S7Q6; -.
DR STRING; 1220924.W2S7Q6; -.
DR GeneID; 19977674; -.
DR VEuPathDB; FungiDB:HMPREF1541_10335; -.
DR eggNOG; KOG2404; Eukaryota.
DR HOGENOM; CLU_011398_4_2_1; -.
DR InParanoid; W2S7Q6; -.
DR OrthoDB; 2667963at2759; -.
DR Proteomes; UP000030752; Unassembled WGS sequence.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR GO; GO:0008202; P:steroid metabolic process; IEA:UniProt.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 2.
DR Gene3D; 3.90.700.10; Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain; 1.
DR InterPro; IPR003953; FAD-binding_2.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR027477; Succ_DH/fumarate_Rdtase_cat_sf.
DR PANTHER; PTHR43400:SF7; FAD_BINDING_2 DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR43400; FUMARATE REDUCTASE; 1.
DR Pfam; PF00890; FAD_binding_2; 1.
DR PRINTS; PR00411; PNDRDTASEI.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
DR SUPFAM; SSF56425; Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain; 1.
PE 4: Predicted;
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000030752}.
FT DOMAIN 47..573
FT /note="FAD-dependent oxidoreductase 2 FAD binding"
FT /evidence="ECO:0000259|Pfam:PF00890"
SQ SEQUENCE 595 AA; 64189 MW; DFBE78E340A8076F CRC64;
MTLRAIDHAR SGSSIIYKLA RSPRKSITST RSFASSATRW QITHSTDVLI VGSGGAGLSA
ALRCHMHGLR PLVIEKSDKL GGTTAWSGGG LWVPNNEQHK SRGVQDSEEQ ALEYLNALIG
DVGPASTPER RLAYVRNASK VVDQLSSMGC RWVPTVGMPD YHSDLPGALE DGRSIEPALV
NAKELGAWKD FLRPPSIFAG PPMHIYEGIV AAKITSWSGI SMLLKILVRW LGHRVMGRDP
VALGQALITH LLKANRDRDT EIWRSTVMQS LSLDESGAVT GAIVVRDGED VRVDAKSIVL
SAGGFAKNDE MRRKYHQQPT DAAWSSVTPN DTGEVIQAGI DIGAATALMS EAWWNPTFLN
PVNGAPWISF GERGRPGTII VDSEGKRFLN EAESYNDAGR RFYERDGTAP AIPAWMVMDS
KFAKRNPLSL IGPRFRKKDS LRTHFLHEAK TLEELSQKIN VDTRNLLATV QRFNGFAKNG
RDEDFGRGGT AMDRLAGDAA AAAGPNPNLG TLEKAPFYAI RIYPGDIGTK GGLLTDEHAR
VLNERGEAIP GLYAAGNTSA SVMGRHYAGA GATIGPAVVF AALAVDHAAG SPWKA
//
