ID W2SJ40_NECAM Unreviewed; 79 AA.
AC W2SJ40;
DT 19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT 19-MAR-2014, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE RecName: Full=Trehalase {ECO:0000256|ARBA:ARBA00019905};
DE EC=3.2.1.28 {ECO:0000256|ARBA:ARBA00012757};
DE AltName: Full=Alpha,alpha-trehalase {ECO:0000256|ARBA:ARBA00030473};
GN ORFNames=NECAME_15585 {ECO:0000313|EMBL:ETN68881.1};
OS Necator americanus (Human hookworm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Strongyloidea; Ancylostomatidae; Bunostominae;
OC Necator.
OX NCBI_TaxID=51031 {ECO:0000313|EMBL:ETN68881.1, ECO:0000313|Proteomes:UP000053676};
RN [1] {ECO:0000313|Proteomes:UP000053676}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=24441737; DOI=10.1038/ng.2875;
RA Tang Y.T., Gao X., Rosa B.A., Abubucker S., Hallsworth-Pepin K., Martin J.,
RA Tyagi R., Heizer E., Zhang X., Bhonagiri-Palsikar V., Minx P., Warren W.C.,
RA Wang Q., Zhan B., Hotez P.J., Sternberg P.W., Dougall A., Gaze S.T.,
RA Mulvenna J., Sotillo J., Ranganathan S., Rabelo E.M., Wilson R.K.,
RA Felgner P.L., Bethony J., Hawdon J.M., Gasser R.B., Loukas A., Mitreva M.;
RT "Genome of the human hookworm Necator americanus.";
RL Nat. Genet. 46:261-269(2014).
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 37 family.
CC {ECO:0000256|ARBA:ARBA00005615}.
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DR EMBL; KI669186; ETN68881.1; -; Genomic_DNA.
DR RefSeq; XP_013291108.1; XM_013435654.1.
DR AlphaFoldDB; W2SJ40; -.
DR STRING; 51031.W2SJ40; -.
DR EnsemblMetazoa; NECAME_15585; NECAME_15585; NECAME_15585.
DR GeneID; 25355611; -.
DR KEGG; nai:NECAME_15585; -.
DR CTD; 25355611; -.
DR OrthoDB; 1329212at2759; -.
DR Proteomes; UP000053676; Unassembled WGS sequence.
DR GO; GO:0004555; F:alpha,alpha-trehalase activity; IEA:UniProtKB-EC.
DR GO; GO:0005991; P:trehalose metabolic process; IEA:InterPro.
DR Gene3D; 1.50.10.10; -; 1.
DR InterPro; IPR008928; 6-hairpin_glycosidase_sf.
DR InterPro; IPR012341; 6hp_glycosidase-like_sf.
DR InterPro; IPR001661; Glyco_hydro_37.
DR Pfam; PF01204; Trehalase; 1.
DR SUPFAM; SSF48208; Six-hairpin glycosidases; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000053676}.
SQ SEQUENCE 79 AA; 8767 MW; 4457244C7A2C56D5 CRC64;
MYGLFAHKWL DPGPAVTITC SHFGVEPQAL NYQLAGRYNV IGDYPRPGSG GEYDVQDGFG
WTNGAILDLL VTYNHRLHN
//
