ID W2SYI4_NECAM Unreviewed; 584 AA.
AC W2SYI4;
DT 19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT 19-MAR-2014, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=ATPase family protein {ECO:0000313|EMBL:ETN74608.1};
GN ORFNames=NECAME_12852 {ECO:0000313|EMBL:ETN74608.1};
OS Necator americanus (Human hookworm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Strongyloidea; Ancylostomatidae; Bunostominae;
OC Necator.
OX NCBI_TaxID=51031 {ECO:0000313|EMBL:ETN74608.1, ECO:0000313|Proteomes:UP000053676};
RN [1] {ECO:0000313|Proteomes:UP000053676}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=24441737; DOI=10.1038/ng.2875;
RA Tang Y.T., Gao X., Rosa B.A., Abubucker S., Hallsworth-Pepin K., Martin J.,
RA Tyagi R., Heizer E., Zhang X., Bhonagiri-Palsikar V., Minx P., Warren W.C.,
RA Wang Q., Zhan B., Hotez P.J., Sternberg P.W., Dougall A., Gaze S.T.,
RA Mulvenna J., Sotillo J., Ranganathan S., Rabelo E.M., Wilson R.K.,
RA Felgner P.L., Bethony J., Hawdon J.M., Gasser R.B., Loukas A., Mitreva M.;
RT "Genome of the human hookworm Necator americanus.";
RL Nat. Genet. 46:261-269(2014).
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DR EMBL; KI660347; ETN74608.1; -; Genomic_DNA.
DR RefSeq; XP_013296835.1; XM_013441381.1.
DR AlphaFoldDB; W2SYI4; -.
DR STRING; 51031.W2SYI4; -.
DR EnsemblMetazoa; NECAME_12852; NECAME_12852; NECAME_12852.
DR GeneID; 25352880; -.
DR KEGG; nai:NECAME_12852; -.
DR CTD; 25352880; -.
DR OrthoDB; 4252119at2759; -.
DR Proteomes; UP000053676; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR011704; ATPase_dyneun-rel_AAA.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR039891; VWA8.
DR PANTHER; PTHR21610; VON WILLEBRAND FACTOR A DOMAIN-CONTAINING PROTEIN 8; 1.
DR PANTHER; PTHR21610:SF9; VON WILLEBRAND FACTOR A DOMAIN-CONTAINING PROTEIN 8; 1.
DR Pfam; PF07728; AAA_5; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000053676}.
FT DOMAIN 16..145
FT /note="ATPase dynein-related AAA"
FT /evidence="ECO:0000259|Pfam:PF07728"
SQ SEQUENCE 584 AA; 66041 MW; A94903F681569507 CRC64;
MSVIRNMARD MRLGAHLLLI GNQGVGKNKI TDRFLHLIQR PRHYMQLHRD TTVESLTMQT
TVENGVLRYE DSALVRAARD GHVLVVDEAD KAPLHVVAFF KSLLDSGTLL LGDGRRIQPA
SAPPRDRSII LHPDFRIIML ANRPGFPFLD VENATLLKLM AAFTELREMV NDGVLQYPYS
IRELVNIAKH INKFPEDSIT AAIRNVFDFD SFSTDAVKLI QEVFQKHGVP FGIEELSKRI
FLSHRFPIDP SSPVGVWGLD SSGASVEVNT NEAHLIVKDC AWQIPMLDVN ICSDGLVVGN
TLVVATVNPP RLYLMRDLNE ANQVHEVDIS PMFKSLRHLL KYQPRLTLST CGNEKILVHE
EVTNSMCIVD LKRDLIQHIN LGSSAFDSLA KILSSSEYRL VRGASTLFAR DGKQLFVIKE
DGFVTLMNLK EEISNVFLLQ EDRYVVKQKN GSYGFLFREG NTWKLQSIST NFTTPIDIDG
ICVHENSVHL SDENFYFLKS GFPLSLDSKE VLGSARHKLS DVVDSRRPHY LSDEETKKFV
NPQRNFVIVR DGVVVRAQPN WNVPKDALKE GELVLLFVCF IYIF
//
