ID W2T974_NECAM Unreviewed; 188 AA.
AC W2T974;
DT 19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT 19-MAR-2014, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE RecName: Full=Reverse transcriptase domain-containing protein {ECO:0000259|PROSITE:PS50878};
GN ORFNames=NECAME_10267 {ECO:0000313|EMBL:ETN78570.1};
OS Necator americanus (Human hookworm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Strongyloidea; Ancylostomatidae; Bunostominae;
OC Necator.
OX NCBI_TaxID=51031 {ECO:0000313|EMBL:ETN78570.1, ECO:0000313|Proteomes:UP000053676};
RN [1] {ECO:0000313|Proteomes:UP000053676}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=24441737; DOI=10.1038/ng.2875;
RA Tang Y.T., Gao X., Rosa B.A., Abubucker S., Hallsworth-Pepin K., Martin J.,
RA Tyagi R., Heizer E., Zhang X., Bhonagiri-Palsikar V., Minx P., Warren W.C.,
RA Wang Q., Zhan B., Hotez P.J., Sternberg P.W., Dougall A., Gaze S.T.,
RA Mulvenna J., Sotillo J., Ranganathan S., Rabelo E.M., Wilson R.K.,
RA Felgner P.L., Bethony J., Hawdon J.M., Gasser R.B., Loukas A., Mitreva M.;
RT "Genome of the human hookworm Necator americanus.";
RL Nat. Genet. 46:261-269(2014).
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DR EMBL; KI659849; ETN78570.1; -; Genomic_DNA.
DR RefSeq; XP_013300797.1; XM_013445343.1.
DR AlphaFoldDB; W2T974; -.
DR EnsemblMetazoa; NECAME_10267; NECAME_10267; NECAME_10267.
DR GeneID; 25350296; -.
DR KEGG; nai:NECAME_10267; -.
DR CTD; 25350296; -.
DR OMA; MHETREM; -.
DR OrthoDB; 3684743at2759; -.
DR Proteomes; UP000053676; Unassembled WGS sequence.
DR CDD; cd01650; RT_nLTR_like; 1.
DR InterPro; IPR043502; DNA/RNA_pol_sf.
DR InterPro; IPR000477; RT_dom.
DR PANTHER; PTHR19446:SF475; REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR19446; REVERSE TRANSCRIPTASES; 1.
DR Pfam; PF00078; RVT_1; 1.
DR SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR PROSITE; PS50878; RT_POL; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000053676}.
FT DOMAIN 1..188
FT /note="Reverse transcriptase"
FT /evidence="ECO:0000259|PROSITE:PS50878"
SQ SEQUENCE 188 AA; 21449 MW; 8CF43857918BB2A7 CRC64;
MKVFECVLEA RLRKIVSVSL NQCGFVKDCS TIDAIHAVRI LLEKHREKSC SVYLAFLDLE
KAFDRVPHEL LWMSMRSHRV PEEYVRWTKL LYAKSTSVVR CAAGTSRPFP VQVGVHQGSS
LSPLLFILCM DTITKEIRGL YSLPMMSCSR RSLEVIFRNK YSLGRIGCRN MDCASTHQKL
STWSADQG
//
