ID W2WIS7_PHYPR Unreviewed; 935 AA.
AC W2WIS7;
DT 19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT 19-MAR-2014, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE RecName: Full=TIR domain-containing protein {ECO:0000259|PROSITE:PS50104};
GN ORFNames=F441_13884 {ECO:0000313|EMBL:ETP10480.1};
OS Phytophthora parasitica CJ01A1.
OC Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC Phytophthora.
OX NCBI_TaxID=1317063 {ECO:0000313|EMBL:ETP10480.1, ECO:0000313|Proteomes:UP000018958};
RN [1] {ECO:0000313|EMBL:ETP10480.1, ECO:0000313|Proteomes:UP000018958}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CJ01A1 {ECO:0000313|EMBL:ETP10480.1,
RC ECO:0000313|Proteomes:UP000018958};
RG The Broad Institute Genomics Platform;
RA Russ C., Tyler B., Panabieres F., Shan W., Tripathy S., Grunwald N.,
RA Machado M., Johnson C.S., Walker B., Young S.K., Zeng Q., Gargeya S.,
RA Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Phytophthora parasitica CJ01A1.";
RL Submitted (NOV-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ETP10480.1}.
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DR EMBL; ANIX01002751; ETP10480.1; -; Genomic_DNA.
DR AlphaFoldDB; W2WIS7; -.
DR EnsemblProtists; ETP10480; ETP10480; F441_13884.
DR Proteomes; UP000018958; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 3.
DR Gene3D; 3.40.50.10140; Toll/interleukin-1 receptor homology (TIR) domain; 1.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR000157; TIR_dom.
DR InterPro; IPR035897; Toll_tir_struct_dom_sf.
DR PANTHER; PTHR24178:SF9; ANK_REP_REGION DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR24178; MOLTING PROTEIN MLT-4; 1.
DR Pfam; PF00023; Ank; 2.
DR Pfam; PF12796; Ank_2; 1.
DR Pfam; PF13676; TIR_2; 1.
DR PRINTS; PR01415; ANKYRIN.
DR SMART; SM00248; ANK; 7.
DR SUPFAM; SSF48403; Ankyrin repeat; 1.
DR SUPFAM; SSF52200; Toll/Interleukin receptor TIR domain; 1.
DR PROSITE; PS50297; ANK_REP_REGION; 4.
DR PROSITE; PS50088; ANK_REPEAT; 6.
DR PROSITE; PS50104; TIR; 1.
PE 4: Predicted;
KW ANK repeat {ECO:0000256|PROSITE-ProRule:PRU00023};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 219..245
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 265..288
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 308..328
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 348..373
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REPEAT 464..496
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 537..565
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 638..670
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 676..708
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 709..741
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 777..809
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT DOMAIN 832..935
FT /note="TIR"
FT /evidence="ECO:0000259|PROSITE:PS50104"
FT REGION 1..152
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 168..192
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 18..37
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 97..114
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 121..151
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 935 AA; 103770 MW; 69ADFD75E0BFC0E4 CRC64;
MEASSPARMA SAELRATVST LPVHQEQSSS SDSDSDVEQS TRSAKAKHIN RQRSNNSRFL
LVPRSSSLGY EPRRPLAETG DPCMLAASES DEVTSLDALE SDTSEQNQNQ EPVDIVVDQE
DVPSSQMSLS TRSQLGYESA PSSSGLDPLS TAERDSISLI KREVLRPPKR SGLPEMTSSR
GEESNRGGPT RRKQVPYAWM LAKLGQKTRR KIGDIRNSYF AGWLVACSLF VVLLNTFAIA
IVQLTYDPEG KIGEDADTRR QCRHWLKLLM TMHFLGLPNI LLIAPVVFPN DFFSLYRAKD
KRMIRRPYLL FCEMIVTIQL GFMMYVAVNQ LLNVPVIVDC HSELKPRQIV LFYSATVLWL
VLLRQIIVFC RFLTHLKLQA DSSNDSSHTS AFGNWFRALK AIPIRSERTR LVKEFKKLLY
RAVARGDVLT VETLLSEAES KYKINRLQDL YKPPVLWFYA FAKSRKNPLH IAVKRGNIRI
VELLLEHGMD VNVLDKVVRV NFNVGLVFKI ISRILVRTQD GLRSPLKTVL CSVLLPPLHG
AVAEGYVDIV RLLISKGADV NALPRASFYY PAAVLPPIFV ADDPQVLRLL VANGANFLQV
ASVSLEGLIR TYATPLQQST FTLRSDLSDY LLECGGDVAL TPLHQAAATD NVGKIKWLLA
RGIRVDTLGE RVEGVHRRTP LHWAAVVGKV NAAKLLLKKG ANPNAKDRDG RTPLHWAARN
NHDEVVSLLL AYNAHPDATD DEGIPVVCFA AEAEGVESSI FSNLVAAGAS LKTQVSGGNT
ALHIALQREN RQTAVSLIKC GSSMMITNDS GKRAVDCTTS TELQFLLKKE AGTRKIMISY
THTHAQFASK VREHLETQEQ LTCWMDTMDP SGIGGGAVWR EEIARGIHNC SLVLSIVCDG
YTKSEWCLKE LALAKLLRKP GTVCSRTFDG FIILC
//
