ID   W2XKI5_PHYPR            Unreviewed;       672 AA.
AC   W2XKI5;
DT   19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT   19-MAR-2014, sequence version 1.
DT   24-JAN-2024, entry version 26.
DE   SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:ETP23166.1};
GN   ORFNames=F441_03659 {ECO:0000313|EMBL:ETP23166.1};
OS   Phytophthora parasitica CJ01A1.
OC   Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC   Phytophthora.
OX   NCBI_TaxID=1317063 {ECO:0000313|EMBL:ETP23166.1, ECO:0000313|Proteomes:UP000018958};
RN   [1] {ECO:0000313|EMBL:ETP23166.1, ECO:0000313|Proteomes:UP000018958}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CJ01A1 {ECO:0000313|EMBL:ETP23166.1,
RC   ECO:0000313|Proteomes:UP000018958};
RG   The Broad Institute Genomics Platform;
RA   Russ C., Tyler B., Panabieres F., Shan W., Tripathy S., Grunwald N.,
RA   Machado M., Johnson C.S., Walker B., Young S.K., Zeng Q., Gargeya S.,
RA   Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA   Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA   Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA   Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA   Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA   Birren B.;
RT   "The Genome Sequence of Phytophthora parasitica CJ01A1.";
RL   Submitted (NOV-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the glycosyl hydrolase 30 family.
CC       {ECO:0000256|ARBA:ARBA00005382}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:ETP23166.1}.
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DR   EMBL; ANIX01000825; ETP23166.1; -; Genomic_DNA.
DR   AlphaFoldDB; W2XKI5; -.
DR   EnsemblProtists; ETP23166; ETP23166; F441_03659.
DR   Proteomes; UP000018958; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0004348; F:glucosylceramidase activity; IEA:InterPro.
DR   GO; GO:0006665; P:sphingolipid metabolic process; IEA:InterPro.
DR   CDD; cd00161; RICIN; 1.
DR   Gene3D; 2.80.10.50; -; 1.
DR   Gene3D; 3.20.20.80; Glycosidases; 1.
DR   Gene3D; 2.60.40.1180; Golgi alpha-mannosidase II; 1.
DR   InterPro; IPR033452; GH30_C.
DR   InterPro; IPR001139; Glyco_hydro_30.
DR   InterPro; IPR033453; Glyco_hydro_30_TIM-barrel.
DR   InterPro; IPR013780; Glyco_hydro_b.
DR   InterPro; IPR017853; Glycoside_hydrolase_SF.
DR   InterPro; IPR035992; Ricin_B-like_lectins.
DR   InterPro; IPR000772; Ricin_B_lectin.
DR   PANTHER; PTHR11069; GLUCOSYLCERAMIDASE; 1.
DR   PANTHER; PTHR11069:SF23; LYSOSOMAL ACID GLUCOSYLCERAMIDASE; 1.
DR   Pfam; PF02055; Glyco_hydro_30; 1.
DR   Pfam; PF17189; Glyco_hydro_30C; 1.
DR   Pfam; PF00652; Ricin_B_lectin; 1.
DR   PRINTS; PR00843; GLHYDRLASE30.
DR   SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR   SUPFAM; SSF50370; Ricin B-like lectins; 1.
DR   PROSITE; PS50231; RICIN_B_LECTIN; 1.
PE   3: Inferred from homology;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Membrane {ECO:0000256|SAM:Phobius}; Signal {ECO:0000256|ARBA:ARBA00022729};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        29..51
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          116..468
FT                   /note="Glycosyl hydrolase family 30 TIM-barrel"
FT                   /evidence="ECO:0000259|Pfam:PF02055"
FT   DOMAIN          524..620
FT                   /note="Ricin B lectin"
FT                   /evidence="ECO:0000259|Pfam:PF00652"
FT   DOMAIN          620..669
FT                   /note="Glycosyl hydrolase family 30 beta sandwich"
FT                   /evidence="ECO:0000259|Pfam:PF17189"
SQ   SEQUENCE   672 AA;  75326 MW;  D66BB29010333739 CRC64;
     MATDFTAYGT SSLASDESLS ARSAARRKWI RWGFISASTG IILAGMVVLG ISSHSVESII
     ATATPDEGDV KCFQSSYVDN VTKMMEPMKG LKWKYGGEKT TDSFIAIDVD TKYQEIMGFG
     GGFTEAAALQ FHKLPKDKQE EVLTLYFDKN KGSAYNFGRV PMGSCDFSMG SYNFAETEND
     MELKDFDVDV THDTEMIIPF IKRALKRRPD MKLILVPWSP PGWMKRSSSS YSASMLGSTK
     PVGLRDDMRA PWALYFSKFI TAYKKHGIPF WGVSPQNEPE FNAPWEACAY NPEYEAEFIG
     EFLGPVLERN HPGVTLMAFD HNRVSVNRWA NVIYSHPSAG KYVDGIAFHW YEDGGERYMD
     GVAYPEHLND THFVNQSRFM LSTESSSCPG VAVGAEAWFR AQRYGHNIMS DLNNYAAGWI
     DWNLILDHTG GPNHKDNVCD AAIIVTEGGD DYFVQPMYYF IQHFSKFLPP GSRRVKTKVA
     ARFAKPGDAQ LFVHYQSSLD SCDGSSRQAI RRTEDNKMQV TGTPFCLDLV NTPTGQHEVR
     LVECQWTPQT WTFEEDTHRV RIDEYCVSLN HGSTEDGVRI MADKCEDEVA LYQQWTFNAE
     DGTMRSHASP SNQCVTAGYS FLQAAAFVAP QNRKVLVVLN ENTEPADFQV QTGNAVLDTT
     IAAGAIRTYV WA
//