ID   W2Y848_PHYPR            Unreviewed;       668 AA.
AC   W2Y848;
DT   19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT   19-MAR-2014, sequence version 1.
DT   27-MAR-2024, entry version 36.
DE   RecName: Full=Tubulin--tyrosine ligase-like protein 5 {ECO:0000256|ARBA:ARBA00041448};
GN   ORFNames=F442_19944 {ECO:0000313|EMBL:ETP31171.1};
OS   Phytophthora parasitica P10297.
OC   Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC   Phytophthora.
OX   NCBI_TaxID=1317064 {ECO:0000313|EMBL:ETP31171.1, ECO:0000313|Proteomes:UP000018948};
RN   [1] {ECO:0000313|EMBL:ETP31171.1, ECO:0000313|Proteomes:UP000018948}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=P10297 {ECO:0000313|EMBL:ETP31171.1,
RC   ECO:0000313|Proteomes:UP000018948};
RG   The Broad Institute Genomics Platform;
RA   Russ C., Tyler B., Panabieres F., Shan W., Tripathy S., Grunwald N.,
RA   Machado M., Johnson C.S., Walker B., Young S.K., Zeng Q., Gargeya S.,
RA   Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA   Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA   Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA   Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA   Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA   Birren B.;
RT   "The Genome Sequence of Phytophthora parasitica P10297.";
RL   Submitted (NOV-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + L-glutamate + L-glutamyl-[protein] = ADP + gamma-L-
CC         glutamyl-L-glutamyl-[protein] + H(+) + phosphate;
CC         Xref=Rhea:RHEA:60144, Rhea:RHEA-COMP:10208, Rhea:RHEA-COMP:15517,
CC         ChEBI:CHEBI:15378, ChEBI:CHEBI:29973, ChEBI:CHEBI:29985,
CC         ChEBI:CHEBI:30616, ChEBI:CHEBI:43474, ChEBI:CHEBI:143622,
CC         ChEBI:CHEBI:456216; Evidence={ECO:0000256|ARBA:ARBA00036640};
CC       PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:60145;
CC         Evidence={ECO:0000256|ARBA:ARBA00036640};
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:ETP31171.1}.
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DR   EMBL; ANIY01004165; ETP31171.1; -; Genomic_DNA.
DR   AlphaFoldDB; W2Y848; -.
DR   EnsemblProtists; ETP31171; ETP31171; F442_19944.
DR   Proteomes; UP000018948; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0036211; P:protein modification process; IEA:InterPro.
DR   CDD; cd00054; EGF_CA; 1.
DR   Gene3D; 3.30.470.20; ATP-grasp fold, B domain; 1.
DR   Gene3D; 2.10.25.10; Laminin; 1.
DR   InterPro; IPR013111; EGF_extracell.
DR   InterPro; IPR004344; TTL/TTLL_fam.
DR   PANTHER; PTHR12241; TUBULIN POLYGLUTAMYLASE; 1.
DR   PANTHER; PTHR12241:SF145; TUBULIN POLYGLUTAMYLASE TTLL5; 1.
DR   Pfam; PF07974; EGF_2; 1.
DR   Pfam; PF03133; TTL; 1.
DR   PROSITE; PS51221; TTL; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000018948};
KW   Signal {ECO:0000256|SAM:SignalP}; Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   SIGNAL          1..27
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           28..668
FT                   /note="Tubulin--tyrosine ligase-like protein 5"
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5004829313"
FT   TRANSMEM        630..651
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          549..573
FT                   /note="EGF-like"
FT                   /evidence="ECO:0000259|Pfam:PF07974"
SQ   SEQUENCE   668 AA;  75465 MW;  969FD2805375218A CRC64;
     MATSLRPHRL HLLLLLVLAV CISVCDSTSA RAQARFYLPE ATQPQKLKPV LQQLQALGIS
     QFQVADSQPS WGKLLSDSSE FDLVWSTAAA PPFEQLELPH QFDAKVNHLP GAEKLTSPDA
     LGQHLVAQQK KRTKFFFDFV PAHFELPRDQ AQLTTAYTEA RKKSDFSPKR GRDPHVQRRF
     LLRDRAVNGD DDSTTCAEVF VTDEDLQFKL QSNTFKGKTV VVDQYVEPLL LDNHKFRVGF
     YVAVTSTDPL RVYVYDHPLI QIAKGEYPST LKVETDPATY NFDQYIAPWD FPDLQTDFHE
     LPSATREGTN AWYVLKKYLR RQGIDTKHLQ DEVEAAIAKV VLSNRGNFQS EQSKVKRSAA
     REGEGSTPND LSDSFFDLWR FDFELDDMAK PWLVRVVSNP SMEGTQSVLA TDEAIKKRLL
     HDLLNLVGVH PQARLPFDKF YRPPADARFC SDKCRDKSRA WDTSCWSCPG WFAPNVARKL
     FTATTEYARR GGFNLIFPSL EQELSKFLDT ELSEFDIAFN RYLKSLSSGY SNLEDFPASD
     RAVVCVYREH CSNHGDCVNG MCLCDSSYEG RTCYIPKDFD QVDHTQHDTG DTGGQDAETW
     KEKVENLVWN RGDAPEGLKR PMTGVGDTSA SGMAFLLVLL CVLLFVIYRV FIAQGSGGTE
     LPHDGKAM
//