ID W3RR91_9BRAD Unreviewed; 393 AA.
AC W3RR91;
DT 19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT 19-MAR-2014, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE SubName: Full=Alcohol dehydrogenase {ECO:0000313|EMBL:ETR79267.1};
GN ORFNames=X566_01280 {ECO:0000313|EMBL:ETR79267.1};
OS Afipia sp. P52-10.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomicrobiales;
OC Nitrobacteraceae; Afipia.
OX NCBI_TaxID=1429916 {ECO:0000313|EMBL:ETR79267.1, ECO:0000313|Proteomes:UP000018975};
RN [1] {ECO:0000313|Proteomes:UP000018975}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=P52-10 {ECO:0000313|Proteomes:UP000018975};
RX PubMed=25874801;
RA Pickering B.S., Tyler S., Smith G., Burton L., Li M., Dallaire A.,
RA Weingartl H.;
RT "Identification of a novel afipia species isolated from an Indian flying
RT fox.";
RL PLoS ONE 10:E0121274-E0121274(2015).
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC Evidence={ECO:0000256|ARBA:ARBA00001947,
CC ECO:0000256|RuleBase:RU361277};
CC -!- SIMILARITY: Belongs to the zinc-containing alcohol dehydrogenase
CC family. {ECO:0000256|RuleBase:RU361277}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ETR79267.1}.
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DR EMBL; AZSJ01000002; ETR79267.1; -; Genomic_DNA.
DR RefSeq; WP_034462826.1; NZ_AZSJ01000002.1.
DR AlphaFoldDB; W3RR91; -.
DR STRING; 1429916.X566_01280; -.
DR PATRIC; fig|1429916.3.peg.255; -.
DR eggNOG; COG1063; Bacteria.
DR OrthoDB; 9773078at2; -.
DR Proteomes; UP000018975; Unassembled WGS sequence.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR CDD; cd08283; FDH_like_1; 1.
DR Gene3D; 3.90.180.10; Medium-chain alcohol dehydrogenases, catalytic domain; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR013149; ADH-like_C.
DR InterPro; IPR013154; ADH-like_N.
DR InterPro; IPR002328; ADH_Zn_CS.
DR InterPro; IPR011032; GroES-like_sf.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR PANTHER; PTHR42813:SF2; DEHYDROGENASE, ZINC-CONTAINING, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G02810)-RELATED; 1.
DR PANTHER; PTHR42813; ZINC-TYPE ALCOHOL DEHYDROGENASE-LIKE; 1.
DR Pfam; PF08240; ADH_N; 1.
DR Pfam; PF00107; ADH_zinc_N; 1.
DR SUPFAM; SSF50129; GroES-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR PROSITE; PS00059; ADH_ZINC; 1.
PE 3: Inferred from homology;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723,
KW ECO:0000256|RuleBase:RU361277};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000018975};
KW Zinc {ECO:0000256|ARBA:ARBA00022833, ECO:0000256|RuleBase:RU361277}.
FT DOMAIN 26..146
FT /note="Alcohol dehydrogenase-like N-terminal"
FT /evidence="ECO:0000259|Pfam:PF08240"
FT DOMAIN 196..265
FT /note="Alcohol dehydrogenase-like C-terminal"
FT /evidence="ECO:0000259|Pfam:PF00107"
SQ SEQUENCE 393 AA; 42442 MW; 228E29E5F075DE85 CRC64;
MKALAWHGVG DIRCESVPDP ALQDDRDIII KVTSCAICGS DLHIFDGMIP EMHKGDILGH
ETMGEVVDVG RQVSSLKVGD RVVVPFTIAC GECFFCTRGY YSACERSNPD KAKAEKLWGH
SPAGLFGYSH ILGGYPGGQA EYLRVPFADA GPLKVPNGLS DDQVLFLSDI FPTGYMAADF
CNIKGGETIA IWGAGPVGQM AIRSAFLLGA ERVVAIDTVP ERLALARQSG AETIDFLAED
VYERLQQITH GRGADACIDA VGTEPNRSSG DRIDQIKLAT YLATDRPYVL RQAIQCCRNF
GTVSIVGVYG GFVDQVPMGS AINRGLSFRM AQTPVQHYLP KLLDLIQSGA IDPSFVVTHR
APLDDGPQLY KTFRDKQDGC IKVVLKPGMQ AAA
//
