ID W4IT53_PLAFP Unreviewed; 440 AA.
AC W4IT53;
DT 19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT 19-MAR-2014, sequence version 1.
DT 27-MAR-2024, entry version 42.
DE RecName: Full=RRM domain-containing protein {ECO:0000259|SMART:SM00360};
GN ORFNames=PFUGPA_04917 {ECO:0000313|EMBL:ETW53290.1};
OS Plasmodium falciparum (isolate Palo Alto / Uganda).
OC Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida;
OC Plasmodiidae; Plasmodium; Plasmodium (Laverania).
OX NCBI_TaxID=57270 {ECO:0000313|EMBL:ETW53290.1, ECO:0000313|Proteomes:UP000019103};
RN [1] {ECO:0000313|EMBL:ETW53290.1, ECO:0000313|Proteomes:UP000019103}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Palo Alto/Uganda {ECO:0000313|EMBL:ETW53290.1,
RC ECO:0000313|Proteomes:UP000019103};
RG The Broad Institute Genome Sequencing Platform;
RG The Broad Institute Genome Sequencing Center for Infectious Disease;
RA Neafsey D., Hoffman S., Volkman S., Rosenthal P., Walker B., Young S.K.,
RA Zeng Q., Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Allen A.W.,
RA Alvarado L., Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J.,
RA Goldberg J., Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A.,
RA Ireland A., Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W.,
RA Priest M., Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J.,
RA Nusbaum C., Birren B.;
RT "The Genome Annotation of Plasmodium falciparum Palo Alto/Uganda.";
RL Submitted (FEB-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ETW53290.1, ECO:0000313|Proteomes:UP000019103}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Palo Alto/Uganda {ECO:0000313|EMBL:ETW53290.1,
RC ECO:0000313|Proteomes:UP000019103};
RG The Broad Institute Genome Sequencing Platform;
RG The Broad Institute Genome Sequencing Center for Infectious Disease;
RA Neafsey D., Cheeseman I., Volkman S., Adams J., Walker B., Young S.K.,
RA Zeng Q., Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Dewar J., Goldberg J., Griggs A.,
RA Gujja S., Hansen M., Howarth C., Imamovic A., Larimer J., McCowan C.,
RA Murphy C., Neiman D., Pearson M., Priest M., Roberts A., Saif S., Shea T.,
RA Sisk P., Sykes S., Wortman J., Nusbaum C., Birren B.;
RT "The Genome Sequence of Plasmodium falciparum Palo Alto/Uganda.";
RL Submitted (FEB-2013) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; KI927386; ETW53290.1; -; Genomic_DNA.
DR AlphaFoldDB; W4IT53; -.
DR EnsemblProtists; ETW53290; ETW53290; PFUGPA_04917.
DR OMA; NDQNSGQ; -.
DR Proteomes; UP000019103; Unassembled WGS sequence.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR CDD; cd12422; RRM2_PTBP1_hnRNPL_like; 1.
DR Gene3D; 3.30.70.330; -; 2.
DR InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR InterPro; IPR021790; PTBP1-like_RRM2.
DR InterPro; IPR035979; RBD_domain_sf.
DR InterPro; IPR000504; RRM_dom.
DR PANTHER; PTHR15592; MATRIN 3/NUCLEAR PROTEIN 220-RELATED; 1.
DR PANTHER; PTHR15592:SF18; SMOOTH, ISOFORM T; 1.
DR Pfam; PF11835; RRM_8; 1.
DR SMART; SM00360; RRM; 2.
DR SUPFAM; SSF54928; RNA-binding domain, RBD; 2.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000019103};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884}.
FT DOMAIN 179..248
FT /note="RRM"
FT /evidence="ECO:0000259|SMART:SM00360"
FT DOMAIN 319..391
FT /note="RRM"
FT /evidence="ECO:0000259|SMART:SM00360"
FT REGION 266..306
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 93..129
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 266..296
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 440 AA; 50922 MW; A92BEA7A7EE3E7FA CRC64;
MNKRTLSDDR NTREKNKVGV KRYLMSSDDI YDNPKLYHEK NNGGSKINMS TFLEINEDGM
LYDNHNNNIM NGHNNDMCDL SNNNNNNNIF NSLNKIDNNN NIKDNEVNKI NNENNNNNIM
NNINNINNNS NNNNNNNNNN GNNCLSTKYY SNDCKKRKGS RYTSSLPFLK KEKNNGNTVL
LLKNVPEKVD EEDIISFMRP FLRNKNPEII FDGQDIIVKL YDDELIESIY TYFNEHPTQI
KGSFVKVKLS HIIDDNKESM EEQNDILNNY NNNNNNYSSS SSNNNNYSFY HTNHNNHPTD
VLDKRNSKSN KAECSKVILV SVINLHYPVD IELIYYLFSK CGTVEKIITF SRNPVLYQAL
VQFDNVETAK EAIKTLHNRN IYDGCNTINI QYSFLKELVI KGNNSSSWDY TISNEKKTKN
FPVLQNSHGV LPTPSRNHKK
//
