ID W4J5P5_PLAFP Unreviewed; 6110 AA.
AC W4J5P5;
DT 19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT 19-MAR-2014, sequence version 1.
DT 27-MAR-2024, entry version 48.
DE RecName: Full=Dynein heavy chain {ECO:0008006|Google:ProtNLM};
GN ORFNames=PFUGPA_01123 {ECO:0000313|EMBL:ETW56922.1};
OS Plasmodium falciparum (isolate Palo Alto / Uganda).
OC Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida;
OC Plasmodiidae; Plasmodium; Plasmodium (Laverania).
OX NCBI_TaxID=57270 {ECO:0000313|EMBL:ETW56922.1, ECO:0000313|Proteomes:UP000019103};
RN [1] {ECO:0000313|EMBL:ETW56922.1, ECO:0000313|Proteomes:UP000019103}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Palo Alto/Uganda {ECO:0000313|EMBL:ETW56922.1,
RC ECO:0000313|Proteomes:UP000019103};
RG The Broad Institute Genome Sequencing Platform;
RG The Broad Institute Genome Sequencing Center for Infectious Disease;
RA Neafsey D., Hoffman S., Volkman S., Rosenthal P., Walker B., Young S.K.,
RA Zeng Q., Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Allen A.W.,
RA Alvarado L., Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J.,
RA Goldberg J., Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A.,
RA Ireland A., Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W.,
RA Priest M., Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J.,
RA Nusbaum C., Birren B.;
RT "The Genome Annotation of Plasmodium falciparum Palo Alto/Uganda.";
RL Submitted (FEB-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ETW56922.1, ECO:0000313|Proteomes:UP000019103}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Palo Alto/Uganda {ECO:0000313|EMBL:ETW56922.1,
RC ECO:0000313|Proteomes:UP000019103};
RG The Broad Institute Genome Sequencing Platform;
RG The Broad Institute Genome Sequencing Center for Infectious Disease;
RA Neafsey D., Cheeseman I., Volkman S., Adams J., Walker B., Young S.K.,
RA Zeng Q., Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Dewar J., Goldberg J., Griggs A.,
RA Gujja S., Hansen M., Howarth C., Imamovic A., Larimer J., McCowan C.,
RA Murphy C., Neiman D., Pearson M., Priest M., Roberts A., Saif S., Shea T.,
RA Sisk P., Sykes S., Wortman J., Nusbaum C., Birren B.;
RT "The Genome Sequence of Plasmodium falciparum Palo Alto/Uganda.";
RL Submitted (FEB-2013) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; KI927296; ETW56922.1; -; Genomic_DNA.
DR EnsemblProtists; ETW56922; ETW56922; PFUGPA_01123.
DR OMA; IAYEYMK; -.
DR Proteomes; UP000019103; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0030286; C:dynein complex; IEA:UniProtKB-KW.
DR GO; GO:0005874; C:microtubule; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0045505; F:dynein intermediate chain binding; IEA:InterPro.
DR GO; GO:0051959; F:dynein light intermediate chain binding; IEA:InterPro.
DR GO; GO:0008569; F:minus-end-directed microtubule motor activity; IEA:InterPro.
DR GO; GO:0007018; P:microtubule-based movement; IEA:InterPro.
DR Gene3D; 1.10.8.1220; -; 1.
DR Gene3D; 1.10.8.710; -; 1.
DR Gene3D; 1.20.1270.280; -; 1.
DR Gene3D; 1.20.58.1120; -; 1.
DR Gene3D; 1.20.920.20; -; 1.
DR Gene3D; 1.20.920.30; -; 1.
DR Gene3D; 3.10.490.20; -; 1.
DR Gene3D; 6.10.140.1060; -; 1.
DR Gene3D; 1.20.140.100; Dynein heavy chain, N-terminal domain 2; 1.
DR Gene3D; 3.20.180.20; Dynein heavy chain, N-terminal domain 2; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 6.
DR Gene3D; 1.10.8.720; Region D6 of dynein motor; 1.
DR InterPro; IPR035699; AAA_6.
DR InterPro; IPR035706; AAA_9.
DR InterPro; IPR041658; AAA_lid_11.
DR InterPro; IPR042219; AAA_lid_11_sf.
DR InterPro; IPR026983; DHC_fam.
DR InterPro; IPR041589; DNAH3_AAA_lid_1.
DR InterPro; IPR042222; Dynein_2_N.
DR InterPro; IPR043157; Dynein_AAA1S.
DR InterPro; IPR041228; Dynein_C.
DR InterPro; IPR043160; Dynein_C_barrel.
DR InterPro; IPR024743; Dynein_HC_stalk.
DR InterPro; IPR024317; Dynein_heavy_chain_D4_dom.
DR InterPro; IPR004273; Dynein_heavy_D6_P-loop.
DR InterPro; IPR013602; Dynein_heavy_linker.
DR InterPro; IPR042228; Dynein_linker_3.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR10676:SF344; DYNEIN AXONEMAL HEAVY CHAIN 5; 1.
DR PANTHER; PTHR10676; DYNEIN HEAVY CHAIN FAMILY PROTEIN; 1.
DR Pfam; PF12774; AAA_6; 1.
DR Pfam; PF12775; AAA_7; 1.
DR Pfam; PF12780; AAA_8; 2.
DR Pfam; PF12781; AAA_9; 1.
DR Pfam; PF17857; AAA_lid_1; 1.
DR Pfam; PF18198; AAA_lid_11; 1.
DR Pfam; PF08393; DHC_N2; 2.
DR Pfam; PF18199; Dynein_C; 1.
DR Pfam; PF03028; Dynein_heavy; 1.
DR Pfam; PF12777; MT; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 4.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW Dynein {ECO:0000256|ARBA:ARBA00023017};
KW Microtubule {ECO:0000256|ARBA:ARBA00022701};
KW Motor protein {ECO:0000256|ARBA:ARBA00023175};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000019103}.
FT DOMAIN 1957..2066
FT /note="Dynein heavy chain linker"
FT /evidence="ECO:0000259|Pfam:PF08393"
FT DOMAIN 2258..2557
FT /note="Dynein heavy chain linker"
FT /evidence="ECO:0000259|Pfam:PF08393"
FT DOMAIN 2701..3032
FT /note="Dynein heavy chain hydrolytic ATP-binding dynein
FT motor region"
FT /evidence="ECO:0000259|Pfam:PF12774"
FT DOMAIN 3774..3845
FT /note="Dynein heavy chain 3 AAA+ lid"
FT /evidence="ECO:0000259|Pfam:PF17857"
FT DOMAIN 4019..4159
FT /note="Dynein heavy chain AAA module D4"
FT /evidence="ECO:0000259|Pfam:PF12780"
FT DOMAIN 4213..4353
FT /note="Dynein heavy chain AAA module D4"
FT /evidence="ECO:0000259|Pfam:PF12780"
FT DOMAIN 4367..4725
FT /note="Dynein heavy chain coiled coil stalk"
FT /evidence="ECO:0000259|Pfam:PF12777"
FT DOMAIN 4754..4977
FT /note="Dynein heavy chain ATP-binding dynein motor region"
FT /evidence="ECO:0000259|Pfam:PF12781"
FT DOMAIN 5393..5502
FT /note="Dynein heavy chain region D6 P-loop"
FT /evidence="ECO:0000259|Pfam:PF03028"
FT DOMAIN 5536..5676
FT /note="Dynein heavy chain AAA lid"
FT /evidence="ECO:0000259|Pfam:PF18198"
FT DOMAIN 5846..6107
FT /note="Dynein heavy chain C-terminal"
FT /evidence="ECO:0000259|Pfam:PF18199"
FT REGION 414..558
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 969..998
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1385..1419
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1529..1559
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1586..1650
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2063..2107
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2160..2192
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 3311..3398
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 3464..3512
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 4155..4216
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 5169..5258
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 764..791
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 4372..4409
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 4605..4681
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 4926..5002
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 425..455
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 456..502
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 505..520
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 521..558
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1529..1555
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1613..1639
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2063..2088
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2089..2107
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2160..2176
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2177..2192
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 3333..3377
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 3378..3393
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 3464..3508
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 4170..4192
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 4193..4210
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 5190..5252
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 6110 AA; 719735 MW; E13856130CCA1A4B CRC64;
MMERKNQDSQ IYNTYKWVLN KLKFSYKEEN NIDYLIDKNI EEKKTVVEKF LCDEENDLLL
FSLENNEMVI AKEENIKFDQ KIVYFYKHLN KNRKDDKKIL YGILSPNILD TLKLMLNKII
YPLFINNKLI NTNVSSDDIN KFMMEFNTYI KELNEFILIL EDIKKVKLRM QIYDSEINND
KKKDENILND EEWEDKNISS CSSSISTIRE FQKKGNESEY KINKKKNETA HLTKYLNILE
NLFNDMQMKI QQYKTSNIDV GPFIEIQYWR YKHRYLLFII EELRSKEIKS IINNININNT
NNEEQKYTYT FDILNKWREL ETKIENEFNE SKDNIKYLES IEQFILSLYL CNVENIIDNI
PSLLNSIKMI YLVARFYNTP NKLNNLFIKI TNQMIIKCKE EIYCAKKKKI RRIKRKQNKG
KNKRNEERRR RDMDGENNED MEDNLYEKND GKNYSTQKNK DNNNNNNNDY DNDNNNVNDD
DNNSDNNSDN NSDNNSHNSN DNESYNYDDD DDDEYYEVNE QEEDHFNGFT RENNYDRDDN
YNNNNYDDGE KHGNRSFENL KDGKKGSIYL NDDIKRDKLK NEEHNLWLLD PDNLIEKFNL
CFKLHEIYKE EFESLKCFFE ENNSTSISVD LNSKVIFCKL EIFCRRLKKL VDLFLCIKQF
QILKSIKFDC VQNITKTFNK YIKEFKLKHT EDMLNYTDNY FDRDFVELRV YISELESDLQ
EHMITLLNNS SNIMLSFFIF FKFKESFIRD YLITFIQTKY DILLQQFLEI LNSINNDLEN
YKNNLSTNKN INYLKNIFWT LSINYKINHI IKIFLDENDN NNNIMYDEKF HINMNTFVNH
DIHKNLKNIG KKKIYNSDKK DSDKEIYKDM EEIKKAPTPD EHIYEKINDK VQIVSSLQQQ
VLELLEDYEK KKNNENVIAH KKEVLSIDKN NHVLKEDVPD DEYKEEIELE KEEKNNFKDK
EEEEKLNEFN KEVKIQKSKP KPKKNYNNNI YNNNNEKKEK EKRKNILFKG GIGKEVLKLY
LKISKFIEEY KNKLFKHWLS YTKNMNSLNV TVFVKHPKTK NIIVNFDNRI KKIIREAKIF
LSFEFELPEE IKNMISQESK IYSFYYKFYN ILILIKKMKS NKKLGIDLSL KYFFIYIDQL
ILPFLVKYTW NNYALEDSID NLFKELYYFD ESINSLYYII KDHIYYNIKL LYKILDYKNE
RLVIHRQKKM FNKRIILCNS ISKKIQIAIF DILSNIQYVY EDKLKSIITK EEIINTRNYY
YEIFLSTLKK IYLKNIKILI NTWSNFDDNN NNNNKGSTQN NMDNMMNYKN MNSDINNNNN
NNDYNYNYNV VEILLLIQEN DIIINPSIKS IKENIKKIIN VSINNLIYID NWITTEDLIR
QFHGNSENEE EHDMEDLSNK TKKRDQIKKR SEQKNEENKF LSNDEIKRKK KKKKNIFDQV
LDFSYFSKNN LNESGNSIEE ELNMENENCV DNLNYYFEFY EKIREDKNIE KELLKLNDKL
FAFQNAVDNF IKKFEKYKYI IKNFHLQKEQ NNNNNNNNSD NNNNNNKSNV IGDYNKQKDM
MNDKILDMDN YMKDREDDEE KERNLLNFTE NEDDLENVNM KSSTKGILDD DNIDNSDDND
SDNNNGDNSD DDDDDDDNNN NNNNNNNFKK YKEEEEKIKK FIEIKKDINN IESCYMLNMF
KFNLESFKMY LINIIENEAL ECAKNVIEPL KKKSDMLIKK INTLKIKLKK KIIDIDSLYY
VINIIKKIHI FESTIDIVLN PINDMLNILE FYMSNFLKKQ MDSLRHSNNY DEEENYQIKF
INNLEKKKSS GQLYNLDDSY NKNLLFTFNK LNVMKKKFVS FYKFEVEKKN LILSKFNELI
NLTKHVEEEI QEKKTTMKNE LINNIYSFKI DIKTFREHFL KMNFKSEHIN PLNAFELLKR
YKEEINMLKN KYNSYYKGES IFGLKHQTHS DLFLSSNEIH NFYSLYDLYV QLKEKLNEWK
NLKWFDGIQK MKELKNEILS FEKKCSQLPK NLKIIVIYKN LMKEIFYFKE ITPIVDELEK
KNILKRHWIE IINILKEKKK KDITGKEKKI QKKSYADEQK DHPKDNINNK SNNNKNNNKN
NNINNNNNQV INEKVHQIDP LVDMEKNNVL EDLNVQQMSN ENKNVKQVEL INDLEHQTNK
TSTQKDVFEK NDNNDNNDKN NINLIHGDTD ENMYNTSEFE DEKMKKKNIE NKKRINDQTD
EEIISKKDIS FQDGGLLEES AYLDEEEYIN NLNKLDLDNM DFFIKDIINY HLLKKKDDIL
DICDSAEKEA SIEEKINEQY KIWNETCFQF SKWKNRDYAC ILVGSKVIEI QESLEESQIL
LNNINSTKYS KPFKSKLLLL LNKLSDCSDI VERWIKVQML WCSMESVFTS GDIARQMPIE
SKRFHQIDKD WINIINIANE SSIVIECCQS SMLKELLPNM QKGLESCQKS LESYLEGKRS
KFPRFYFVSN LVLLKILSQG SDINIIQSEL IKLFDAINYL TIKTIQNKKR IICINNKEKD
DIETVQLVNH VTIDGNIENW LILLEKEMQK AIKKECKLGV SNSSQLFKTL NLKEFCDKNI
AQVALICLQV MWTNDIEKCI YKYHSEKNIL KVTNKKINYI MSELVNICLS DLGTKLNRTK
YETLVTIHVH QRDLFTEISA KIKEHKIKTT TDFDWIKQTR IYYKVEKNII LISISDVDFI
YSYEYLGIKE RLCITPLTDR CYLTCAQALG LCYGGAPAGP AGTGKTETVK DLGRTLGIYV
IVTNCSNQHK YKDMAKIFKG LCRSGLWGCF DEFNRINLDV LSVVAMQIES IVTAKKQSLK
YFLFPGDSKS INLNPSSAYF ITMNPGYAGR QLLPENLKIF FRFISMMVPD RQIIIKVKLA
SVGYLDIDNL SNKFKSLYNL CEEQLSKQKH YDFGLRNILS VLRTAGDTKR SAGPNENDEE
MLLMRTLRDM NLSKLIHDDV LLFLSLLNDV FPKFHNITKK SFQLIEENVL QIIKKKKLCA
KGKWILKILQ LYETSLVRHG FMLVGNTLTG KTEILNILTS ALTNIGSVTK IITLNPKAIT
SEHMYGVKDN LSEEWTPGIF ANIWEKYNNN NLKYNTWIVC DGPVDAIWIE NLNTVLDDNK
ILTLANNDRI PMTDNTKIAF EVENLNNASP ATVSRAGIVY ISDSDLGYRP FIYSWLQKLK
DINTYGMTLY AIFNKLFIFY LDKIQILSFL KENCKFVMDI TDSILILQTI NLLNSQIIQY
INAINNFMYN EEDLNKIFFL DTNEKKLLPH SQKLIKSNIE EENNIYEQEN GIPSSEMKKG
KDQLLNDEKY KSSNKLEDTK NMTLPNDLGK KPLFPTLEKK NDKYGKNLDN IKNEQKDQND
EEKNKKMDKK EADHDQQQDE EEKEQEEEYD DDTKLDGINN YTLSSGTKYE KVNIDECEEI
MLYSIVWGLC GLLEYKDRLK VHNFLLKNVP VLKNVMGVNK KLYTEENEKK KQQQPKKKKE
LQPKGDYNDY VSTKQNKEED KNNIELDNEQ NVEDGEEFEN EISLIYDFYF DMKLKKLVKW
NVGPFKMPRN INSISSILIP TIETTKVEHI IKLISNIPIR CYNFHTYKST LLLGSTGSAK
TSIALLYTSK QEKNTKRFNF SSVTTPEKFQ LFIESELERK TGKTYGPIGN TKSIIFIDDM
SMPKINEWGD QSTLELLRQL IEFQGFYFLD KDKRGNFKKI IDLEYIGCIN HPGCGNNDIP
KRLKSKWFNV NILPYNLNSI NTIYGTVLRT KFNKKQNFSD EIIENIDKVI LCTINLFGRL
KKHLLPVPSR FHYLYTTRDL AKIFYSMLLC PYESIDNNLY NFLCLWKHEC ERVLIDKLSR
MEDKTFSLDQ LKQIFNQYYP SYKDICEKNI YFSYFYVSEK EQQLYMIEND LIENNTTQEK
TENNKINITI SPSYINDTSN NLISTKLDNT NELNEKIDDT KTRSNSALYR RNDVDNQNII
NNNNILTKEG DNNGDIDNIN TFSFSWMKKD YKIVVDFERL RYIVYEYMKE YNINNVKKLD
LVFFDDSLKH LIIINRVMQT PNGSCMLVGV GGSGKRSLTK LSVFISEQVL FQLNITKTYT
KNLFFEDLKS LYISAGQMNK KTTFLLSDSD IEKNDFILEH VNSILSTGLV YGLFIKDEKE
AICAEMKESY LKEMNKSNQS SKIKGGKKKK NKNDYNNIDD MDMDEFHSKD SQSKSDASST
SSIDNDSISN ENITNKKKKK DEKVINDFNV SSNVIFDYLL DNVRNNLHIF LCFSPIHKEF
ALRYQQFPCI YNCVTINWFL KWPLEALVNV STAYLNNFNI DIEDNLKDDF FNLFAIVHNK
VSDTCDTYKE RMRRNTYVTP KSYLSFIDLY KQMYVKKYDE IKCLKESVDI GLKKLNEAAM
DVQKMRESLT SEEEKLKESD EQMNILLEKV KDESLKAEKQ SVEVSKFRDK CIKEKDLILK
DQEEADKDLK AALPYLHEAE EAIKSITGKD ITELKSMKTP SDIIRIVFDG VLILLQGKLK
EPKIDVKYVN KQHIDFIQDS FDEYAKPLMA DIRFLNLLFD FSKNEKDNIN EETIELLKPY
IQSTFFKTQI AKKASVAAEG LCKWVGAMAM YNQASKIVKP KMSYLKIQTG RLEDALKQLA
EAEDSLLKAQ LFVENLNLDI ENMFKKKKAL EETALKTKQR IEQANKLING LSSEKDRWTD
DSNNFSNIKK KIVGDVFICS SFITYCGMFN TEFRNYLMND VFYNYTKNIK NIPVSSNIDI
IKYVLSSDDT KICDWSVQKL PNDKLSIENA LICENSNKYV LLIDPQCQAS NWIKNKEFQN
DLSNQRCITT FNSTKFKDNL EYCLSEGKTL LIENVEEYID PILDSVLEKQ IIKKGKKNYI
LIENNLINFD EKFNLFMTTN IPNPNYSPEI YARCCVIDFT VTVKGLEDQL LGRVLTEEQK
HLEITLKNIM IELKDNTKSL QDLDKQLLYK LNTSSSNLIE DEELIEVLNN TKLLSKELES
KLKDSNEKKK EINEKREQYR SVALRGSILY FCIVDITNVN YIYNTSLHQF LEQFDLSIKK
AEKGQHIKKR VESILYTLTN LIISYMERCL FDHHKIIFKL LISLKILLYD NIISNKDISF
FLNPLSHYSP SNDMNNEMTN TNMLNDPMDV LKNKKNKKNN KEMINNNNNM SIAINAVINN
TMDSSSMNND TMNVYLGTNE NDKNKKDTNT SDVMSSSSST KTGSRTTTTT TTTTTTTNNN
NNNNNMDGNS SNNAGNINSC KNNTSVTDHN ISNKNKIDLH KKGAGKGKIS STKWLFKNEK
LYKNIISLSN HSFGNDKNNR FFYDILNVIQ LNENTWKNYY DILDIENKNI PYYNERLDVN
SQISSFIKLC LIRCLREDRT ILCANKFVDE VLNRNSDTIK HETLENIFSE SSNRKPFLFL
LSLASDPTNM IDDFAKKFKK YPTDKISMGE GQEVIAKEKL KNGIISGNWL ILQNCHLNKN
FIIDVYNMLK NLNEIEEDFR LFLTSEPDDE FPICILHGSI KISTSLSSGI KNNMRKIYKD
IIKEDILEKI DDDKYRKIIY SLSYLHCVLC ERKKFGPLGW CVPYEFSITD LFASYLFIEK
HLYSTLLVNR PIDWESIHYM LAEVQYGGKV TDDLDRELLL TYVQYYFNED LFRMKSEGSS
EYLNLPKFYE ITNFKNFIEK IPNIDTPSVL DLHNNAEITY RVNESRQVLN SILEIQPRDV
DQGEEKSMET VVQEMCLGIL QNLPTDINLE DVKKILYRKN KNIQPNMQTN TQLNVTCNLG
ATTKNFGILE NSSYKGKNRD YNIDTNDNVN NNILQKSVML NNPNNYTANV GKYIIPGDNK
NKNLGLVKEN ELSLDIPDIA YWENDNEGEK NVQYNFSPLQ VFFLQEMERI KKVIDLVKVN
LNDIISAIDG SKIMTADLQN DTKYIFSQSV PKKWIYDASE TEISWICNNL NQWLNILNLR
YEQIMNYIYN GKLKSYWLPG FFNPQGFLTS MKQEITRLNK KDQLSLDEVV LYTDIKNYDV
EKIKEFPEHG FNIHGLFIEG SKWNWQEGKL EESSPKILCE NMPVIHITVV SNKDKKIKFI
ENNKHMFYNC PVYKYNVRTD KYFIFRIHLK SDIDPSIWKL RGTSLLCSKD
//
